Results 71 to 80 of about 2,144 (117)

[<i>Lactobacillus plantarum</i> alleviates lead exposure-induced learning and memory impairment in mice by regulating bile acid metabolism and inhibiting hippocampal NLRP3 expression]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li L, Yu W, Tan M, Li Y, Liu A, Meng X.
europepmc   +1 more source

β-淀粉样肽对海马 CA1 区神经元的 短暂性外向 K+电流的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 1998
目的: 为了在离子通道水平探讨β-淀粉样肽( β-AP)在 Alzheimer 病中的作用。方法: 用 7～ 21 d 大鼠,以链霉蛋 白酶 E 酶解加吸管吹打法制备海马 CA1区神经元; 利用全细胞膜片钳技术, 观察了β-AP25～ 35对急性分离海马 CA1 区锥体细 胞的短暂性 K+电流的影响。结果: β-AP25～ 35对短暂性 K+电流有明显抑制作用, 且呈明显浓度依赖性、时间依赖性和部分电 压依赖性。结论: β-AP 对 K+通道的影响在 Alzheimer 病的发生机制中具有重要作用 ...
doaj  

[C1q-neutralizing antibodies improves postpartum depressive-like behaviors in mice by regulating the C1q/C3 pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Sun Y, Xu X, Zhuo X, Cai H, Wang Y.
europepmc   +1 more source

[<i>Chaihu Shugan</i> Decoction improves cognitive impairment after epilepsy in rats by regulating hippocampal NMDAR subunits <i>via</i> upregulating ASIC1]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Yu Y, Xie W, Li H.
europepmc   +1 more source

[<i>Qixiong Zuogui</i> Granules enhance synaptic plasticity in aging rats by regulating the BDNF/TrkB signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang Q, Zhao X, He Y, Liu F, Zhang Y.
europepmc   +1 more source

七氟醚对小鼠海马区BDNF-TrkB-CREB 信号通路表达影响及其氧化应激机制研究 附视频

Zhongguo shiyan zhenduanxue
目的 从动物实验角度分析七氟醚对小鼠海马区BDNF-TrkB-CREB信号通路表达影响，并探讨其氧化应激机制。方法 以32只6～7周龄SPF级健康雄性C57BL/6小鼠为研究对象，遵循随机化原则及等额原则分为对照组/实验组，每组16只。对照组予生理盐水，腹腔注射，连续注射5 d;采用颈椎脱臼法将小鼠处死。实验组行七氟醚吸入诱导，七氟醚挥发罐开至8%,氧流量6 L/min,监测七氟醚的呼出浓度；待小鼠麻醉成功后采用颈椎脱臼法将小鼠处死。取固定后的小鼠海马组织，依次放入梯度酒精溶液逐步脱去组织水分 ...
doaj   +2 more sources

[Depressive disorders and olfactory dysfunction]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Tang Y, Zou L, Chen X, Yan C.
europepmc   +1 more source

[Potential biological mechanisms underlying spaceflight-induced depression symptoms in astronauts]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Li Z, Liu J, Liu B, Wang M, Ju Y, Zhang Y.   +5 more
europepmc   +1 more source

[Synchronized neural rhythms in rat hippocampal CA1 region and orbitofrontal cortex are involved in learning and memory consolidation in spatial goal-directed tasks]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Tang L, Li J, Xu H.
europepmc   +1 more source

[Role of the Nrf2/HO-1 pathway in cypermethrin-induced oxidative injury of mice hippocampal neurons]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhou L, Zhang X, Yu Y, Zhang P.
europepmc   +1 more source