[<i>Trillium tschonoskii</i> Maxim saponin protects neurological function in rats with post-stroke cognitive impairment by promoting ER-phagy]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoYang D +5 more
europepmc +1 more source
β-淀粉样肽对海马 CA1 区神经元的 短暂性外向 K+电流的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 1998 目的: 为了在离子通道水平探讨β-淀粉样肽( β-AP)在 Alzheimer 病中的作用。方法: 用 7～ 21 d 大鼠,以链霉蛋 白酶 E 酶解加吸管吹打法制备海马 CA1区神经元; 利用全细胞膜片钳技术, 观察了β-AP25～ 35对急性分离海马 CA1 区锥体细 胞的短暂性 K+电流的影响。结果: β-AP25～ 35对短暂性 K+电流有明显抑制作用, 且呈明显浓度依赖性、时间依赖性和部分电 压依赖性。结论: β-AP 对 K+通道的影响在 Alzheimer 病的发生机制中具有重要作用 ...
doaj
[Electroacupuncture improves post-traumatic stress disorder in rats by alleviating hippocampal mitochondrial injury <i>via</i> regulating Bcl-2/Bax/caspase-3 signaling]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoMa D, Cheng J, Zhang H, Liu G, Song K.
europepmc +1 more source
[KLF10 overexpression alleviates neuroinflammation and anxiety-depressive disorder in rats by downregulating the NF-κB/NLRP3 pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLiu A, Guo W, Li J, Zhang T, Xu D.
europepmc +1 more source
[<i>Qingre Lidan Jiedu</i> Recipe improves high copper load-induced cognitive dysfunction in rats by regulating mitophagy]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoWang Y +6 more
europepmc +1 more source
七氟醚对小鼠海马区BDNF-TrkB-CREB 信号通路表达影响及其氧化应激机制研究 附视频
Zhongguo shiyan zhenduanxue目的 从动物实验角度分析七氟醚对小鼠海马区BDNF-TrkB-CREB信号通路表达影响，并探讨其氧化应激机制。方法 以32只6～7周龄SPF级健康雄性C57BL/6小鼠为研究对象，遵循随机化原则及等额原则分为对照组/实验组，每组16只。对照组予生理盐水，腹腔注射，连续注射5 d;采用颈椎脱臼法将小鼠处死。实验组行七氟醚吸入诱导，七氟醚挥发罐开至8%,氧流量6 L/min,监测七氟醚的呼出浓度；待小鼠麻醉成功后采用颈椎脱臼法将小鼠处死。取固定后的小鼠海马组织，依次放入梯度酒精溶液逐步脱去组织水分 ...
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[C1q-neutralizing antibodies improves postpartum depressive-like behaviors in mice by regulating the C1q/C3 pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoSun Y, Xu X, Zhuo X, Cai H, Wang Y.
europepmc +1 more source
[<i>Lactobacillus plantarum</i> alleviates lead exposure-induced learning and memory impairment in mice by regulating bile acid metabolism and inhibiting hippocampal NLRP3 expression]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLi L, Yu W, Tan M, Li Y, Liu A, Meng X.
europepmc +1 more source
Shuitu Baochi Xuebao目的为定量评估云南省植被固碳提升潜力的空间格局，揭示其与国家重点生态功能区的空间关系。方法以植被净初级生产力（net primary productivity）为核心指标，综合运用气候模型、时空替代模型和遥感观测最大值模型，通过多模型模拟结果对比分析，评估植被固碳提升潜力的分布特征。结果1）云南省植被固碳提升潜力值为68.25~277.44 Mt（以C计），3种模型的评估结果在量值上存在一定差异，时空替代模型最为乐观，遥感观测最大值模型最为保守。2）植被固碳提升潜力与植被类型及海拔梯度密切相关 ...
章译文 +4 more
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[<i>Chaihu Shugan</i> Decoction improves cognitive impairment after epilepsy in rats by regulating hippocampal NMDAR subunits <i>via</i> upregulating ASIC1]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoYu Y, Xie W, Li H.
europepmc +1 more source