Results 1 to 10 of about 14,071 (197)
Biomarkers of malignant transformation in oral leukoplakia: from bench to bedside. [PDF]
J Zhejiang Univ Sci B, 2023 Cai X, Zhang J, Zhang H, Li T.
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Promising roles of non-exosomal and exosomal non-coding RNAs in the regulatory mechanism and as diagnostic biomarkers in myocardial infarction. [PDF]
J Zhejiang Univ Sci B, 2023 Li J +7 more
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Zhongshan Daxue xuebao. Yixue kexue ban糖尿病肾脏疾病（DKD）已成为我国慢性肾脏病（CKD）的首位住院病因，也是终末期肾脏病（ESRD）和新增血液透析的主要原因。DKD具有起病隐匿，知晓率低，病情持续进展，预后差等特点，目前仍缺乏治疗的特效药物及方法。准确评估和识别DKD临床预后不良的高风险患者，及早进行干预，对提高DKD患者生存率和生活质量、改善预后具有重要意义。目前DKD预后评估的方法主要包括病理分型、临床指标、数学模型以及生物标志物，多种方法为DKD预后的早期预测及干预提供了手段，但各有利弊。本文对近年研究进展进行综述 ...
李安岚, 盛梅笑
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Application of Biomarker Detection of Exhaled Air Condensate in Respiratory Diseases [PDF]
, 2022 Respiratory diseases are getting more and more attention, and their complex and changeable symptoms have brought a series of challenges to medical treatment.
XU Baichuan, LI Yiting, ZHAO Hulei, ZHANG Peng, XIE Yang
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Progress in functional mechanisms and biomarkers of miRNA related to Kawasaki disease [PDF]
, 2023 Kawasaki disease is an acute febrile exanthema pediatric disease with systemic vasculitis as the main lesion, which is the most common cause of acquired heart disease in children.
DUAN Junkai, FENG Jiali, PENG Yu
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Proteomic Difference Analysis of Whole Blood and Bloodstains [PDF]
, 2023 Objective To study the changes of protein levels in peripheral blood after it dried. Methods The proteins from whole blood and bloodstains were detected by liquid chromatography-tandem mass spectrometry （LC-MS/MS） and normalized by the label-free ...
Ao HUANG, Shu-bo WEN, Qian-qian KONG, Zhen-min ZHAO, Xi-ling LIU
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Sequential Changes of Serum Biomarkers after Skeletal Muscle Contusion in Rats [PDF]
, 2020 Objective To screen serum biomarkers after skeletal muscle contusion in rats based on gas chromatography- mass spectrometry （GC- MS） metabolomics technology, and support vector machine （SVM） regression model was established to estimate skeletal muscle ...
ZHAI Hao-jie, LIN Wei, TIAN Tian, et al.
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Progress in Research on Biomarkers of Post-Traumatic Epilepsy [PDF]
, 2020 Post traumatic epilepsy （PTE） is a serious complication of traumatic brain injury and a difficult problem in forensic justice practice. In recent years, many biomarkers have been applied to the diagnosis, treatment and prognosis of injuries and diseases.
JIA Xiao, ZHOU Feng-juan, DAI Bin-bin,et al
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Zhongguo cuzhong zazhi, 2019 目前认为脑小血管病（cerebral small vessel disease，CSVD）的主要机制是血管内皮损伤，而 炎症和血管内皮损伤密切相关，血清中血管内皮损伤相关标志物及炎性标志物是反映炎症损伤血管 内皮最直接、最简便的方法。关于生物标志物的研究为更深入了解CSVD的发生发展机制提供了重要 的途径。目前多项研究表明炎性及血管内皮损伤相关标志物与CSVD的发生、发展关系密切。另外炎症 与CSVD关系也可能受到人种、遗传等因素的影响。本文就血清中血管内皮相关标志物、炎性标志物与 ...
钟曦，王伊龙
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, 2017 目的：为借助分子影像技术提高抗肿瘤药物研发效率、降低研发成本提供参考。方法：以“分子影像技术”“药物研发”“肿瘤诊断”“生物标志物”等为关键词，通过检索和筛选中国知网、中国国家图书馆、PubMed、WebofScience等数据库收录的2017年4月以前发表的分子影像技术用于抗肿瘤药物研发的最新文献，进行整理、归纳和综述。结果与结论：近年来分子影像技术已取得重大进展，正越来越广泛地应用于抗肿瘤药物研发，并在药物生物分布标志物（药物由血液循环运送到体内各脏器的过程）、药效学生物标志物 ...
任恩, 刘刚, 高海燕
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