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Application of Biomarker Detection of Exhaled Air Condensate in Respiratory Diseases [PDF]
, 2022 Respiratory diseases are getting more and more attention, and their complex and changeable symptoms have brought a series of challenges to medical treatment.
XU Baichuan, LI Yiting, ZHAO Hulei, ZHANG Peng, XIE Yang
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Progress in functional mechanisms and biomarkers of miRNA related to Kawasaki disease [PDF]
, 2023 Kawasaki disease is an acute febrile exanthema pediatric disease with systemic vasculitis as the main lesion, which is the most common cause of acquired heart disease in children.
DUAN Junkai, FENG Jiali, PENG Yu
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Sequential Changes of Serum Biomarkers after Skeletal Muscle Contusion in Rats [PDF]
, 2020 Objective To screen serum biomarkers after skeletal muscle contusion in rats based on gas chromatography- mass spectrometry （GC- MS） metabolomics technology, and support vector machine （SVM） regression model was established to estimate skeletal muscle ...
ZHAI Hao-jie, LIN Wei, TIAN Tian, et al.
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, 2017 目的：为借助分子影像技术提高抗肿瘤药物研发效率、降低研发成本提供参考。方法：以“分子影像技术”“药物研发”“肿瘤诊断”“生物标志物”等为关键词，通过检索和筛选中国知网、中国国家图书馆、PubMed、WebofScience等数据库收录的2017年4月以前发表的分子影像技术用于抗肿瘤药物研发的最新文献，进行整理、归纳和综述。结果与结论：近年来分子影像技术已取得重大进展，正越来越广泛地应用于抗肿瘤药物研发，并在药物生物分布标志物（药物由血液循环运送到体内各脏器的过程）、药效学生物标志物 ...
任恩, 刘刚, 高海燕
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Progress in Research on Biomarkers of Post-Traumatic Epilepsy [PDF]
, 2020 Post traumatic epilepsy （PTE） is a serious complication of traumatic brain injury and a difficult problem in forensic justice practice. In recent years, many biomarkers have been applied to the diagnosis, treatment and prognosis of injuries and diseases.
JIA Xiao, ZHOU Feng-juan, DAI Bin-bin,et al
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Proteomic Difference Analysis of Whole Blood and Bloodstains [PDF]
, 2023 Objective To study the changes of protein levels in peripheral blood after it dried. Methods The proteins from whole blood and bloodstains were detected by liquid chromatography-tandem mass spectrometry （LC-MS/MS） and normalized by the label-free ...
Ao HUANG, Shu-bo WEN, Qian-qian KONG, Zhen-min ZHAO, Xi-ling LIU
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Zhongguo cuzhong zazhi, 2019 目前认为脑小血管病（cerebral small vessel disease，CSVD）的主要机制是血管内皮损伤，而 炎症和血管内皮损伤密切相关，血清中血管内皮损伤相关标志物及炎性标志物是反映炎症损伤血管 内皮最直接、最简便的方法。关于生物标志物的研究为更深入了解CSVD的发生发展机制提供了重要 的途径。目前多项研究表明炎性及血管内皮损伤相关标志物与CSVD的发生、发展关系密切。另外炎症 与CSVD关系也可能受到人种、遗传等因素的影响。本文就血清中血管内皮相关标志物、炎性标志物与 ...
钟曦，王伊龙
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Zhongguo shiyan zhenduanxue, 2022 阿尔茨海默病(AD)是一种进行性认知功能障碍为核心的中枢神经系统变性病[1],患者不仅存在脑组织结构和功能的异常,还有脑分子代谢改变。阿尔茨海默病生物标志物是评估疾病病理生理学特征的客观量化指标[2],近年来NIA-AA[3]提出AT(N)研究框架,其将生物标志物β-淀粉样蛋白(Aβ)沉积(A)、
李佳霖 +5 more
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Clinical value of alpha-fetoprotein: alpha-fetoprotein-L3 isoform ratio and des-γ-carboxyprothrombin in early diagnosis of HBV-related hepatocellular carcinoma [PDF]
, 2023 Objective To evaluate the value of different combinations of alpha-fetoprotein （AFP）， alpha-fetoprotein-L3 isoform ratio （AFP-L3%） and des-γ-carboxyprothrombin （DCP） for early diagnosis of hepatitis B virus （HBV）-related hepatocellular carcinoma （HCC ...
Duan Jianping, Du Lei, Song Ting, Liu Zhensheng
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Feasibility study of utilizing multi-biomarkers in Sebastiscus marmoratus to monitor marine combined pollution [PDF]
, 2015 生物标志物检测技术具有效应快、灵敏度高和特异性强的优点，已广泛应用于细菌、寄生虫、病毒等方面的定性检测。但目前对于生物标志物的研究以室内为主，现场应用较少。许多在室内研究中与污染物有较好相关性的生物标志物在现场应用中却不甚理想。因此，将室内研究结果推广到现场检测研究具有十分重要的意义。 在复杂的海洋环境中，单一生物标志物只能从某一层面反应污染物的生物效应，建立一套多生物标志物的生物检测技术就显得尤为重要。综合生物标志物响应指数法(Integratedbiomarkerresponse，IBR ...
陈晔
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