Results 11 to 20 of about 17,224 (167)
Lessons from an eradication under multiple constraints of an island rat population of record density
Conservation Biology, Volume 40, Issue 2, April 2026.Abstract Invasive rats threaten island biodiversity, disrupting ecosystems and endangering native species. Although rat eradication has succeeded on many islands, tropical islands present unique management challenges. Strict regulations and financial constraints on some tropical islands further limit proven eradication methods, complicating rodent ...
Tatiane Micheletti +7 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 376-384, March 2026.ABSTRACT Objective To investigate whether combining abnormal morphological features observed on ultrasound in live pregnancies that ended in a first‐trimester miscarriage can predict an abnormal karyotype. Methods This retrospective observational cohort study was conducted at the early‐pregnancy assessment unit at University College London Hospital ...
T. Setty +5 more
wiley +1 more source
Metabolomic Study on the Advanced Pancreatic Cancer Model in Nude Mouse [PDF]
, 2016 胰腺癌是一种恶性程度极高的消化道类恶性肿瘤，早期无显著病征，病人在确诊时病情基本已处于中晚期，而研究显示，直径小于2cm和1cm的胰腺癌术后5年生存率分别可达30%-60%和超过75%，远高于中晚期术后5年生存率。 本文为课题“基于核磁共振的代谢组学技术发现胰腺癌的生物标志物及早期诊断应用”的一部分。整个课题目的在于通过系统分析动物和人类胰腺癌中晚期模型代谢通道的异同点，然后通过构建动物早期胰腺癌模型，并结合中晚期动物与人类胰腺癌代谢通路的共同点 ...
李志水
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Clinical value of alpha-fetoprotein: alpha-fetoprotein-L3 isoform ratio and des-γ-carboxyprothrombin in early diagnosis of HBV-related hepatocellular carcinoma [PDF]
, 2023 Objective To evaluate the value of different combinations of alpha-fetoprotein （AFP）， alpha-fetoprotein-L3 isoform ratio （AFP-L3%） and des-γ-carboxyprothrombin （DCP） for early diagnosis of hepatitis B virus （HBV）-related hepatocellular carcinoma （HCC ...
Duan Jianping, Du Lei, Song Ting, Liu Zhensheng
core +1 more source
Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin +4 more
wiley +1 more source
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang +7 more
wiley +1 more source
肾透明细胞癌患者术前血浆GAPDH cfNA水平对诊断及预后的价值
Zhongguo shiyan zhenduanxue, 2021 肾透明细胞癌（ccRCC）是最常见的肾恶性肿瘤[1],但由于缺乏特异性的生物标志物,目前临床上对于ccRCC预后的判断仍然依赖患者或肿瘤的临床和病理特征。寻找一种有效的生物标志物对于ccRCC患者的术后检测以及管理至关重要[2]。循环肿瘤细胞（CTCs）已经被证明在肾细胞癌患者的早期诊断和预后中具有潜在的应用价值[3-4]。
邱实, 陈坤, 衣琳, 于越海
doaj
Activatable Ferritin Nanocomplex for Real-Time Monitoring of Caspase-3 Activation during Photodynamic Therapy（PDT） [PDF]
, 2016 随着分子影像学的发展，治疗诊断学已成为现在医学研究的热点。目前各种 先进的医学成像技术已被用在医学成像，例如光学成像，磁共振成像(MRI），单 光子发射计算机断层扫描（SPECT），正电子发射断层扫描（PET）和光声成像， 从而促进了分子成像探针和医学成像的发展。分子成像探针结构复杂，能够结合 特定生物标志物并产生成像信号用于疾病的诊断。迄今为止，一些成像探针已应 用到临床，例如18F-FDG，但是探针的低靶向性特点限制了成像探针的应用。因 此 ...
王静静
core
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2023 人中性粒细胞载脂蛋白(human neutrophil li- pocalin, HNL)以45 kD二硫键连接的同源二聚体存在，是诊断急性细菌感染性疾病的生物学标志物[1-4]。近年来研究发现HNL在感染性疾病中显著升高，HNL作为新型生物标志物在感染性疾病中研究众多，现就此综述如下。1 中性粒细胞载脂蛋白的生物学特性中性粒细胞载脂蛋白是中性粒细胞二级颗粒的主要成分，由180个氨基酸残基组成的相对质量为45 kD的多肽链，
杜丽敏, 张洁, 赵凤芹
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