Results 41 to 50 of about 1,543 (117)
Zhongguo shiyan zhenduanxue, 2013 急性肾损伤在临床非常常见,其发病率和死亡率都很高,所以选择合适的生物标志物对早期肾损伤进行检测有着非常重要的意义。目前急性肾损伤中最常用的生物标志物仍为血肌酐（SCr）、尿素氮（BUN）,近年来一些新的生物标志物陆续被应用,如中性粒细胞相关载脂蛋白（NGAL）、胱抑素C（cystatin C）、肾脏损伤分子1（KIM-1）、白细胞介素18（IL-18）等,各有优缺点。本文介绍了一种新的肾损伤检测标志物丛集素（Clusterin）,主要介绍丛集素在检测急性肾损伤中所表现出来的敏感、快速与准确的特性。
邹颖刚 +5 more
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The metabolism of endogenous lipids in hepatocellular carcinoma [PDF]
, 2015 研究背景：原发性肝细胞癌（以下简称原发性肝癌）是肝脏主要的恶性肿瘤，由于其起病隐匿，进展迅速，确诊时大多数患者已达到晚期或发生远处转移，治疗困难，因此提高原发性肝癌的诊断及愈后至关重要。有研究证明内源性大麻素系统可以通过多条通路产生抗肿瘤作用，但其与原发性肝癌发生发展的关系及治疗作用尚未完全阐明。 目的：本课题通过相关实验技术研究内源性大麻素系统与原发性肝癌之间的内在联系，探讨相关机制，以期发现原发性肝癌发生早期的生物标志物；并通过调控内源性脂质，探讨有效治疗原发性肝癌的特异性靶标。 方法 ...
李蕾
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The homogenization of China's city flowers and city trees
People and Nature, Volume 7, Issue 2, Page 530-540, February 2025.Abstract Cultural homogeneity, similar to the loss biodiversity, is a significant global issue that is increasingly gaining attention. City flowers and city trees (CFTs) serve as emblematic cultural symbols of modern cities, often referred to as the ‘green business card’. While many cities have established CFTs in recent decades, there are instances of
Zhuo Cheng +6 more
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Shuitu Baochi Xuebao, 2005 水是环境中污染物迁移的重要介质,水系污染物也可以直接作用于生物体。本文概述了对水系物质迁移过程示踪的各种方法,包括人工示踪剂方法、生物标志法、微量元素及同位素示踪方法等,指出了它们的环境应用价值。在人工示踪法中叙述了中子活化示踪沙技术和稀土元素-DTPA螯合物示踪法。生物标志物主要叙述了木质素、正构烷烃、脂肪酸的指示意义。微量元素示踪主要涉及到Sr、Ca、Mg和REE的示踪。同位素示踪法着重阐述了较先进的碳、氮、氧和铅同位素的示踪。最后展示了水系物质示踪的应用前景。
李阿梅 袁旭音 乔磊
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The development for emerging biomarkers of lymphangioleiomyomatosis
Orphanet Journal of Rare Diseases抽象 Lymphangioleiomyomatosis (LAM) is a rare, slowly progressing, low-grade metastatic tumor primarily affecting women. Currently, vascular endothelial growth factor–D (VEGF-D) is the only validated diagnostic biomarker, enabling diagnosis of LAM without ...
Liting Huang +3 more
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The value of biomarkers in the diagnosis and prognostic analysis of IgA nephropathy [PDF]
Immunoglobulin A nephropathy （IgAN） is the most common primary glomerulonephritis worldwide and the main cause of chronic kidney disease and renal failure worldwide.
Li Gui-sen, Lu Min
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Conservation Biology, Volume 39, Issue 1, February 2025.Abstract Trade restrictions are often advocated and implemented as measures to protect wild species threatened by overexploitation. However, in some instances, their efficacy has been questioned, notably by governments in the southern African (SADC) region, which tend to favor a sustainable use approach to wildlife management. We conducted a systematic
Christina Hiller +1 more
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液相色谱-质谱联用技术筛查synemin蛋白及其在肾癌诊断中的作用
Zhongguo shiyan zhenduanxue, 2020 目的本研究的目的是利用化学和生物信息学的方法寻找肾癌和癌旁组织的差异蛋白,探讨目标蛋白作为肾癌生物标志物的可能性。方法采用液相色谱-质谱法鉴定肾癌和癌旁组织差异表达的蛋白,借助免疫组织化学的方法观察肾癌和癌旁组织标本中synemin蛋白的表达。结果肾癌与癌旁组织差异表达的蛋白有26个,肾癌组织中过表达18个,低表达8个。synemin蛋白在肾癌组织中的高表达,统计学差异明显 ...
谭文佳 +3 more
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Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 4, Page 470-479, October 2024.ABSTRACT Objectives Our aim was to examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy‐number variants (pCNVs). We also wanted to quantify the performance of combined first‐trimester screening (cFTS) and a second‐trimester anomaly scan in detecting these aberrations. Finally, we aimed
K. Gadsbøll +6 more
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Conservation Biology, Volume 38, Issue 3, June 2024.Abstract Reintroduced populations are typically considered to progress through establishment, growth, and regulatory phases. However, most reintroduction programs do not monitor intensively enough to test this conceptual model. We studied population indices derived from track activity of 4 threatened species (greater bilby [Macrotis lagotis], burrowing
Katherine E. Moseby +3 more
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