Results 11 to 20 of about 211 (67)
浙江大学学报. 医学版病毒诱导的衰老（VIS）是一种重要的生物学现象，对机体产生多方面影响，包括免疫系统功能下降、衰老相关疾病的发生发展以及机体的加速老化。多种常见RNA病毒（严重急性呼吸综合征冠状病毒2型）、DNA病毒（疱疹病毒、乙型肝炎病毒等）以及蛋白质病毒（朊病毒）均能诱导宿主细胞发生VIS，主要涉及cGAS-STING信号通路的异常激活及DNA损伤应答等机制，也可能与细胞内相分离引起的整合应激反应相关。研究发现，病毒感染与细胞衰老之间的作用是相互的。细胞衰老是宿主细胞限制病毒复制和传播的一种防御机制 ...
常 允闯 +4 more
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Policy &Internet, Volume 16, Issue 3, Page 485-508, September 2024.Abstract During the COVID‐19 pandemic, some groups and individuals rearticulated state power through conspiracy theories. Despite their fringe status, conspiracy theory beliefs can directly animate citizen's engagements with institutions. Drawing on Barkun's ‘conventional’ and ‘stigmatised’ knowledge types, we analyse the appearance of conspiracism in ...
Ben Lyall, Patrick Marple
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Developmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019 目的 本国际临床指南由欧洲残疾儿童学会（the European Academy of Childhood Disability，EACD）牵头制定，旨在解决发育性协调障碍（developmental coordination disorder，DCD）的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题，通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础，以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类，最终转化为指南建议。并由国际 ...
Jing Hua +6 more
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“We are adapting to it because it is within us”: The co‐becoming of COVID‐19 in Malawi
World Medical &Health Policy, Volume 16, Issue 3, Page 295-315, September 2024.Abstract Using a case study design, this research explores the Coronavirus 2019 disease (COVID‐19) pandemic from the perspectives and worldviews of Malawians (Black/African knowledge) through the Bawaka Yolŋu ontology of co‐becoming (Black/Indigenous knowledge).
Chúk Odenigbo +3 more
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General Psychiatry, Volume 30, Issue 3, Page 188-198, July 2018., 2018 Background The abuse of methamphetamine (METH) has become a public health problem worldwide. This type of new drug can not only lead to addiction but can also cause cognitive impairment. Currently, there is no effective treatment. Repetitive transcranial magnetic stimulation (rTMS) is a painless and non‐invasive green physiotherapy which can be used in
Xueqing Wu +3 more
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Risk, Hazards &Crisis in Public Policy, Volume 15, Issue 1, Page 6-24, March 2024.Abstract The COVID‐19 crisis posed challenges for policy‐makers, experts, and citizens alike. Current research often focuses on the interlinkage between scientific expertise and political decision‐making, but ethical expertise remains largely overlooked.
Theresa Sommer +2 more
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World Medical &Health Policy, Volume 16, Issue 1, Page 57-69, March 2024.Abstract Human consumption of sea turtles remains prevalent throughout Mexico even though laws restricting trade and take of threatened and endangered species have been in place for several decades. The illegal consumption of sea turtles represents a risk to animal conservation, and the pathogens in the meat can adversely affect human health.
A. Alonso Aguirre +6 more
wiley +1 more source
浙江大学学报. 医学版副黏病毒是一类重要的呼吸道病原体，在儿童感染性疾病中具有重要临床意义。其感染过程中可诱导多种形式的程序性细胞死亡（PCD），这些PCD形式在病毒复制、传播及宿主免疫应答中发挥关键作用，显著影响病毒的生命周期及疾病进展。一方面，PCD通过清除被感染细胞有助于限制病毒扩散并激活宿主免疫应答，从而增强抗病毒防御能力；另一方面，过度或异常的细胞死亡可能导致组织损伤和免疫紊乱，为病毒复制提供有利环境，进而加重病情。如细胞凋亡通过外源性与内源性通路参与感染控制，同时亦可能被病毒操控以增强其扩散能力 ...
刘 叶 +3 more
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European Policy Analysis, Volume 10, Issue 1, Page 84-100, Winter 2024.Abstract The article discusses the role of parliamentary oversight of emergency measures and policies in increasing democratic resilience and recovery from the COVID‐19 pandemic. The study on the Finnish Parliament is conducted by analyzing the statements of the Constitutional Law Committee, whose role is to conduct a parliamentary constitutional ...
Mikko Värttö
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Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】探讨钝顶螺旋藻多糖(PSP)抗单纯疱疹病毒2型(HSV-2)的作用及可能机制,为进一步开发该药提供理论依据。【方法】实验选用HSV-2标准株(333株),以不同剂量的PSP作用于HSV-2复制周期的不同阶段,终点以病毒半数感染量(TCID50)、细胞病变效应(CPE)、MTT染色细胞保护率(MTT法)及荧光定量PCR(FQ-PCR)作为评价手段,判断PSP的抗病毒效果。【结果】PSP对Vero细胞毒性极低(TC50为1750μg/mL),对HSV-2无直接灭活作用 ...
朱萧, 于红, 张文卿
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