Results 11 to 20 of about 29,206 (132)
[Causal relationship between circulating cytokines and keloids: A Mendelian randomized study]. [PDF]
目的 瘢痕疙瘩是一种以异常纤维化和高复发率为特征的皮肤纤维增生性疾病,其发生和发展与炎症介质密切相关。然而,现有流行病学研究受限于混杂因素和反向因果干扰,难以明确二者的因果关系。因此本研究采用孟德尔随机化(Mendelian randomization,MR)分析研究循环细胞因子与瘢痕疙瘩的因果关系。 方法 从全基因组关联研究(genome-wide association study,GWAS)数据中提取与瘢痕疙瘩(结局)显著相关的循环细胞因子(暴露)单核苷酸多态性(single nucleotide
Chen X, Deng K, Zhou J, Liu C.
europepmc +2 more sources
[Clinical study of the cytokine panel in the diagnosis of ocular chronic graft-versus-host disease]. [PDF]
目的 探索细胞因子与眼部慢性移植物抗宿主病(cGVHD)的相关性,筛选眼部cGVHD的特异性生物标志物。 方法 通过建立小鼠cGVHD模型,探讨cGVHD与血清细胞因子相关性。根据动物实验结果和文献检索,确定了16种细胞因子组合,使用酶联免疫吸附试验(ELISA)比较从2017年6月至2022年3月在陆军军医大学新桥医院血液病医学中心接受异基因造血干细胞移植后发生眼部cGVHD和未发生眼部cGVHD患者的血清与泪液细胞因子表达水平。 结果 ①与对照组比较,cGVHD小鼠血清IL-1β、IL-6、IL-8、
Cheng XJ +8 more
europepmc +2 more sources
ABSTRACT Objective Complete hydatidiform mole and coexisting normal fetus (CHMCF) is a rare condition for which there is significant heterogeneity in diagnosis, counseling and management of complications. The objective of this study was to summarize the prevalence of clinical outcomes in reported cases of CHMCF.
N. Salmeri +8 more
wiley +1 more source
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
wiley +1 more source
ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley +1 more source
Boron Difluoride Chelated Aminoanthraquinone Photosensitizer for Type I Photodynamic Therapy
ABSTRACT Type I photosensitizers capable of generating cytotoxic reactive oxygen species (ROS), with reduced oxygen dependence under photoirradiation, are regarded as a promising phototherapeutic approach for hypoxic solid tumors. Herein, based on the electron donor of 9‐phenyl‐carbazole (Cz) and the electron acceptor of anthraquinone (AQ ...
Tian Zhang +8 more
wiley +1 more source
Review of additively manufactured zinc alloys by laser powder bed fusion for biomedical applications
Graphical abstract AbstractZinc (Zn) and its alloys have emerged as promising candidates for biomedical materials, owing to their controlled degradation kinetics, intrinsic biocompatibility, and the release Zn2+ ions which are known to promote bone regeneration and tissue healing.
Xuan Yang +5 more
wiley +1 more source
A new beef: An analysis of discourse coalitions in the nascent cellular agriculture policy subsystem
Abstract A robust approach to examining the nature and influence of coalitions in the policy process is the Advocacy Coalition Framework (ACF), which is especially useful to study policy issues fraught with scientific and technical controversy. Yet, important gaps exist in ACF literature regarding nascent policy subsystems. Consequently, there is scant
Nikki Nadeau, Ramiro Berardo
wiley +1 more source
Summary Abscisic acid (ABA) induces stomatal closure, reducing transpirational water loss, a critical adaptation for agriculture under drought. However, ABA is often viewed cautiously as stomatal closure limits CO2 uptake for photosynthesis and growth.
Jinghui Liu +4 more
wiley +1 more source

