Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa [PDF]
, 2018 Objective To evaluate the performance of diagnostic tools for diabetes mellitus, including laboratory methods and clinical risk scores, in newly-diagnosed pulmonary tuberculosis patients from four middle-income countries.
Alisjhabana, B +19 more
core +2 more sources
Feasibility of using teleradiology to improve tuberculosis screening and case management in a district hospital in Malawi. [PDF]
, 2012 Malawi has one of the world's highest rates of human immunodeficiency virus (HIV) infection (10.6%), and southern Malawi, where Thyolo district is located, bears the highest burden in the country (14.5%).
Brant, W E +6 more
core +2 more sources
A tuberculosis nationwide prevalence survey in Gambia, 2012. [PDF]
, 2016 OBJECTIVE: To estimate the population prevalence of active pulmonary tuberculosis in Gambia. METHODS: Between December 2011 and January 2013, people aged ≥ 15 years participating in a nationwide, multistage cluster survey were screened for active ...
Adetifa, Ifedayo Mo +15 more
core +1 more source
Tuberculosis in the aftermath of the 2010 earthquake in Haiti. [PDF]
, 2015 PROBLEM: In 2010, Haiti sustained a devastating earthquake that crippled the health-care infrastructure in the capital city, Port-au-Prince, and left 1.5 million people homeless.
Collins, Sean E +11 more
core +1 more source
Integrating tuberculosis and antimicrobial resistance control programmes. [PDF]
, 2018 Many low- and middle-income countries facing high levels of antimicrobial resistance, and the associated morbidity from ineffective treatment, also have a high burden of tuberculosis. Over recent decades many countries have developed effective laboratory
Hanefeld, Johanna +3 more
core +2 more sources
Evaluation of anatomical and visual function for early detection of ethambutol toxicity among tuberculosis patients [PDF]
, 2017 AIM: To evaluate if early ethambutol toxicity can be detected by comparing pre - and post - treatment anatomical and visual function using retinal nerve fiber thickness, pattern visual evoked potentials and conventional optic nerve function tests ...
Mohd Noor, Raja Azmi +5 more
core +2 more sources
Zhongguo shiyan zhenduanxue, 2021 结核病是由结核分枝杆菌复合群感染导致的慢性疾病,结核病是一个威胁人类健康的全球性公共卫生问题[1]。非结核分枝杆菌(NTM)是指除结核分枝杆菌复合群和麻风分枝杆菌以外的分枝杆菌。在发达国家和发展中国家,肺非结核分枝杆菌病的患病率呈增加趋势[2-9]。因临床上肺结核与肺非结核分枝杆菌病临床表现相似,均痰检抗酸杆菌阳性,易导致误诊,NTM对某些常用的抗结核药天然耐药,造成患者久治不愈[10-12],不能得到及时的诊治,
朱文芳, 张宜文
doaj
Biochemical characteristics and function studies of Esx-1 secretion-associated protein EspL and EspG1 [PDF]
, 2016 由巨噬细胞等人体免疫细胞聚集形成的肉芽肿是结核病的形成标志，肉芽肿的形成在结核分枝杆菌的致病过程中扮演着重要角色，它使被感染的宿主与结核分枝杆菌融合在一起。结核分枝杆菌通过特异性的蛋白分泌系统Esx-1分泌系统将具有毒性作用的毒力因子通过高疏水性的细胞膜分泌到胞外。这些毒力因子与宿主中肉芽肿的形成以及结核分枝杆菌毒性作用有关。EspL是结核分枝杆菌Esx-1分泌系统中的一个重要的蛋白，已有研究表明EspL可能通过影响另外两个毒力因子EspE和ESAT-6的分泌而调控肉芽肿的形成 ...
田双良
core
A New Type of Spacer Oligonucleotide Typing for Mycobacterium Tuberculosis Complex and Clinical Evaluation [PDF]
, 2016 结核病是当今世界范围内对人类健康最具威胁的传染性疾病之一，具有潜伏感染的特点，因此追踪传染源和查证传播途径是长期困扰结核病流行病学研究的一个问题，也是分子流行病学要解决的首要问题。基因分型技术是分子流行病学研究的一个有力工具，在研究结核病传播规律方面有着不可替代的优势。一个理想的基因分型技术应当具备简便、快速、结果可在不同实验室间进行比较等特点。本论文基于探针熔解曲线分析技术，建立新型的快速结核分枝杆菌分型体系，并评价其临床应用。论文内容如下： 第一章为绪论，首先概述了结核病目前的流行情况 ...
曾小红
core
The new electrochemical DNA sensor for detection of Mycobacterium tuberculosis and its drug resistance gene [PDF]
, 2016 耐药结核分枝杆菌，尤其是耐多药结核分枝杆菌的出现给结核病的检测和治疗带来了巨大的挑战，对人类健康产生了极大威胁。目前临床上常用的结核病的检测方法分别存在操作繁琐、仪器昂贵、耗时较长及易污染等不足。电化学DNA传感器是近几年发展起来的一种新型生物传感器，因其简单、灵敏、特异性强、易微型化等特点受到研究者的青睐，已被应用于多个领域的研究。然而电化学DNA传感器易受其他因素的干扰造成结果不稳定。实验前期构建的BSA单分子层控制组装界面为基础的电化学DNA传感器，有效地提高了体系的稳定性。本文在前期研究基础上 ...
李茜茜
core