Results 101 to 110 of about 1,834 (143)

程序性坏死参与大鼠肠缺血再灌注所致肺损伤的发生

Zhongshan Daxue xuebao. Yixue kexue ban, 2017
【目的】探讨程序性坏死是否参与肠缺血再灌注所致肺损伤的发病机制。【方法】雄性SD大鼠32只，随机分 为4组（n = 8）：假手术组（sham组）、肠缺血再灌注组（I/R组）、程序性坏死特异性抑制剂Necrostatin?1组（Nec-1组）和溶剂二 甲基亚砜组（DMSO组）。采用夹闭肠系膜上动脉1.5 h再灌注6 h的方法制备肠缺血再灌注损伤模型。sham组仅分离血管； Nec-1组及DMSO组分别于夹闭肠系膜上动脉前30 min时腹腔注射Necrostatin?11.0 mg ...
温仕宏, 刘克玄
doaj  

[Xenon post-conditioning protects against spinal cord ischemia-reperfusion injury in rats by downregulating mTOR pathway and inhibiting endoplasmic reticulum stress-induced neuronal apoptosis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2022
Luo L, Tong J, Li L, Jin M.
europepmc   +1 more source

异搏定和能量合剂对肠缺血再灌注所致肝损伤的保护作用

Zhongshan Daxue xuebao. Yixue kexue ban, 2008
【目的】 通过建立肠缺血—再灌注的动物实验模型,研究异搏定65380;能量合剂对大鼠肠缺血—再灌注所致肝损伤的作用65377; 【方法】 将32只Wistar大白鼠,随机分为A65380;B65380;C65380;D四组65377;B65380;C65380;D三组分别与再灌注前静注生理盐水65380;异搏定65380;能量合剂注射液,以A组为对照65377;测定所有动物血清中ALT,AST和LDH含量,血清和肝组织中超氧化物歧化酶(SOD)65380;丙二醛活性(MDA ...
doaj  

ＵＷ 液动脉预灌洗对缺血肢体再灌注损伤的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2013
【目的】 评估ＵＷ液动脉预灌洗对缺血肢体Ｉ／Ｒ损伤程度的影响，寻找减轻缺血组织Ｉ／Ｒ损伤的有效方式。【方法】 建立大鼠后肢缺血模型，预灌洗组于肢体恢复血供前，应用ＵＷ液预灌洗３０ｍｉｎ，然后恢复血供；缺血再灌注组不进行预灌洗直接恢复肢体血供，每组８只。通过监测骨骼肌再灌注血流量变化，测定血清ＣＰＫ、ＬＤＨ含量及骨骼肌水含量、ＭＤＡ含量、ＳＯＤ活性、骨骼肌细胞凋亡情况以及骨骼肌的超微结构改变，来评估骨骼肌的Ｉ／Ｒ损伤程度。【结果】 恢复血供后，Ｉ／Ｒ组中骨骼肌血流过度灌注明显，峰值为健侧（２１６ ± ２２）
doaj  

[Resveratrol protects barrier function of mouse brain microvascular endothelial cell monolayers with oxygen/glucose deprivation and PM_2.5 exposure by maintaining mitochondrial dynamics balance]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Qin M, Sun S, Liu J, Gao Y, Wang H, Wang Y, Sun A, Yan J, Wang J, Yu Y.   +9 more
europepmc   +1 more source

[Electroacupuncture improves learning and memory function and promotes hippocampal synaptic regeneration in rats with cerebral ischemia-reperfusion injury]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Lin R, Xia J, Ma X, Li Z.
europepmc   +1 more source

[Asiaticoside alleviates myocardial ischemia-reperfusion injury in rats by inhibiting NLRP3 inflammasome-mediated pyroptosis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Bian F, Ni S, Zhao P, Qi M, Tang B, Wang H, Kang P, Liu J.   +7 more
europepmc   +1 more source

[<i>In vitro</i> cultured calculus bovis alleviates cerebral ischemia/reperfusion injury through regulating microglial polarization and inhibiting NLRP3]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Chu T, Zhang W, Chen J, Pan Z, Wang L, Zhong X, Qiu F, Huang Z.   +7 more
europepmc   +1 more source

Pharmacological inhibition of ENaC or NCX can attenuate hepatic ischemia-reperfusion injury exacerbated by hypernatremia. [PDF]

J Zhejiang Univ Sci B
Chen Y, Li H, Wen P, Zhang J, Wang Z, Cao S, Guo W.   +6 more
europepmc   +1 more source

[Electroacupuncture pretreatment alleviates cerebral ischemia-reperfusion injury in rats by inhibiting ferroptosis through the gut-brain axis and the Nrf2/HO-1 signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhang A, Sun X, Pang B, Wu Y, Shi J, Zhang N, Ye T.   +6 more
europepmc   +1 more source