【目的】 通过建立肠缺血—再灌注的动物实验模型,研究异搏定65380;能量合剂对大鼠肠缺血—再灌注所致肝损伤的作用65377; 【方法】 将32只Wistar大白鼠,随机分为A65380;B65380;C65380;D四组65377;B65380;C65380;D三组分别与再灌注前静注生理盐水65380;异搏定65380;能量合剂注射液,以A组为对照65377;测定所有动物血清中ALT,AST和LDH含量,血清和肝组织中超氧化物歧化酶(SOD)65380;丙二醛活性(MDA ...
doaj
【目的】 评估UW液动脉预灌洗对缺血肢体I/R损伤程度的影响,寻找减轻缺血组织I/R损伤的有效方式。【方法】 建立大鼠后肢缺血模型,预灌洗组于肢体恢复血供前,应用UW液预灌洗30min,然后恢复血供;缺血再灌注组不进行预灌洗直接恢复肢体血供,每组8只。通过监测骨骼肌再灌注血流量变化,测定血清CPK、LDH含量及骨骼肌水含量、MDA含量、SOD活性、骨骼肌细胞凋亡情况以及骨骼肌的超微结构改变,来评估骨骼肌的I/R损伤程度。【结果】 恢复血供后,I/R组中骨骼肌血流过度灌注明显,峰值为健侧(216 ± 22)
doaj
[Resveratrol protects barrier function of mouse brain microvascular endothelial cell monolayers with oxygen/glucose deprivation and PM<sub>2.5</sub> exposure by maintaining mitochondrial dynamics balance]. [PDF]
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Pharmacological inhibition of ENaC or NCX can attenuate hepatic ischemia-reperfusion injury exacerbated by hypernatremia. [PDF]
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[Electroacupuncture pretreatment alleviates cerebral ischemia-reperfusion injury in rats by inhibiting ferroptosis through the gut-brain axis and the Nrf2/HO-1 signaling pathway]. [PDF]
Zhang A +6 more
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LncRNA AK154753 mediates the development of acute kidney ischemia reperfusion injury via the miR<b>-</b>345<b>-</b>3p/Bak and miR<b>-</b>708<b>-</b>5p/Bim pathways. [PDF]
Wen Y +7 more
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