目的检测多重耐药的铜绿假单胞菌中整合子系统的分布和耐药基因携带情况,并探讨整合子系统的分布与多重耐药的关系。方法选取2012年5月至2012年10月由大连医科大学附属第一医院住院患者各种标本中分离的多重耐药的铜绿假单胞菌148株,提取全基因组DNA,通过PCR方法扩增Ⅰ、Ⅱ、Ⅲ类整合子和相关耐药基因bla CTX-M、bla SHV、bla VIM、bla IMP、OPrD2、aadA、aadB,并通过凝胶电泳方法对扩增结果进行分析。结果在多重耐药的铜绿假单胞菌中I类整合子阳性检出率为56.1%(83 ...
肖晓光, 李艳莲, 孙国华
doaj
A single-center retrospective study of pathogen distribution and antibiotic resistance of bloodstream infections in emergency department. [PDF]
Tang Y +6 more
europepmc +1 more source
Mechanisms of Acquired Resisitance to EGFR Tyrosine Kinase Inhibitors in Non-small Cell Lung Cancer [PDF]
Hongjie LI, Xiaoping LI
core
[Distribution and Drug Resistance Characteristics of Pathogenic Bacteria in the Elderly Population in China in 2021]. [PDF]
Tang S +12 more
europepmc +1 more source
[Chinese expert consensus on the diagnosis and treatment strategies for refractory/resistant cytomegalovirus infection in immunocompromised populations (2025)]. [PDF]
Infectiology Group +6 more
europepmc +1 more source
Future of PARP inhibitors in cancer treatment: overcoming resistance and enhancing efficacy with combination therapies. [PDF]
Shoaib M +6 more
europepmc +1 more source
[Application of Nano-drug Delivery Technology in Overcoming Drug Resistance in Lung Cancer]. [PDF]
Lu Y, Wang C, Liu B.
europepmc +1 more source
[Distribution of the Pathogens Isolated from 6428 Tumor Patients in 2019-2023 and the Relevant Drug Resistance Surveillance Report]. [PDF]
Tang Q +5 more
europepmc +1 more source
[METTL3-mediated m<sup>6</sup>A modification promotes FOXO3 expression and anthracycline resistance in acute myeloid leukemia cells through autophagy regulation]. [PDF]
Zhang X +5 more
europepmc +1 more source

