Results 21 to 30 of about 47,270 (166)
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu +12 more
wiley +1 more source
ABSTRACT The escalating issue of drug‐resistant pathogens, largely driven by the overuse of conventional antibiotics, has become a significant global health threat. Developing alternative therapeutic strategies and fabricating natural biological enzyme materials that mimic the high efficiency, selectivity, and mild‐operating conditions of natural ...
Shuai He +11 more
wiley +1 more source
为了鉴定小熊猫(Ailurus fulgens)肺源致病菌并研究其耐药性和耐药基因,从死亡小熊猫肺部组织中无菌分离培养致病菌,进行革兰氏染色及16S rDNA测序鉴定。采用纸片扩散法(KB法)进行细菌药敏试验和小鼠致病性试验,应用PCR法检测分离株的28种β内酰胺酶相关基因、6种氨基糖苷类修饰酶基因(AMEs)、外膜蛋白D2基因(oprD2)、磺胺耐药基因(qacE△1sul1)、3种整合子基因(intⅠ1、2、3)和主动外排泵调节基因(mexR)等共40种耐药基因 ...
邹洁建 古河祥 翟俊琼 萨家祺 陈武 杜雪晴
core
2014年~2017年某院复治肺结核患者的耐药情况分析 [PDF]
目的了解我院复治肺结核涂阳患者的耐药谱,为我院预防和治疗结核病提供依据。方法 2014年1月至2017年12月在我院结核病门诊诊断和治疗的涂阳肺结核患者的痰培养结核分枝杆菌,鉴定为结核分枝杆菌的菌株采用比例法,使用6种抗结核药物[异烟肼(H)、利福平(R)、乙胺丁醇(E)、链霉素(S)、氧氟沙星(Ofx)、卡那霉素(Km)]测试耐药性。结果 350例复治肺结核患者的总耐药率为41.71%(146/350),单药耐药(SDR)率为10.25%,多耐药(PDR)率为6.85%,耐多药(MDR)率为24.57%
卢惠萍
core +1 more source
To Ban or Not to Ban: The UK's Hamlet Moment With Farm Antibiotics
ABSTRACT This article applies the Multiple Streams Framework (MSF) to examine post‐Brexit antimicrobial resistance (AMR) governance in UK agriculture, focusing on the contested regulation of prophylactic antibiotic use in farm animals. The study reveals how Brexit created a structural policy window, yet political and ideological dynamics rendered it ...
George Asiamah
wiley +1 more source
ABSTRACT Background Chronic cases of canine otitis externa (OE) often develop infections with Pseudomonas aeruginosa (PA). Given the organism's high level of resistance, veterinary surgeons often turn to compounded solutions. Limited data describing the stability and potency of compounded ceftazidime (CAZ) solutions are available, which may affect ...
McKenna Snidow +6 more
wiley +1 more source
Background: Inhibition of the Janus kinase pathway is an established treatment for allergic dermatitis. Objective: To evaluate the efficacy and safety of ilunocitinib for control of pruritus in dogs with allergic dermatitis in a randomised, double‐masked clinical trial.
Sophie Forster +5 more
wiley +1 more source
为了解耐甲氧西林葡萄球菌的耐药状况,并为临床预防与治疗提供依据,我们对61株葡萄球菌进行耐甲氧西林及14种常用抗菌素的耐药率测定。结果:耐甲氧西林金黄色葡萄球菌检出率为52.6%;耐甲氧西林凝固酶阴性葡萄球菌检出率为47.6%;耐甲氧西林葡萄球菌对14种抗菌素的耐药率及多重耐药性均高于甲氧西林敏感葡萄球菌。耐甲氧西林葡萄球菌对万古霉素敏感 ...
童青, 方莹
core
Background – Canine superficial bacterial folliculitis (SBF) is a common recurrent condition with a growing requirement for culture and susceptibility as a consequence of increased antimicrobial resistance and antimicrobial stewardship. Different opinions persist about the ideal technique for culture sample acquisition, which varies with lesion ...
Jason B. Pieper +3 more
wiley +1 more source

