Results 41 to 50 of about 16,300 (168)

血清CA153、BXTM及CEA联合检测对乳腺癌的早期诊断价值比较

open access: yesZhongguo shiyan zhenduanxue, 2020
目的分析血清肿瘤标志物CA153、BXTM与CEA单独及联合检测对乳腺癌的早期诊断价值。方法选择2014年2月-2015年1月来我院诊治的疑似乳腺癌患者286例,均行病理活检,采用酶联免疫法检测血清肿瘤标志物CA153、BXTM与CEA,比较乳腺癌及乳腺良性病变患者各指标差异,分析三指标单独检测及联合检测对乳腺癌的诊断效能。结果 286例患者病理检测确诊为乳腺癌108例,乳腺良性病变178例。乳腺癌患者血清CA153、CEA及BXTM水平均明显高于乳腺良性病变患者 ...
陈琛   +6 more
doaj  

Application of Flow Cytometric Bead Array Combined with Rolling Circle Amplification on the Multiplexed Detection of Tumor Markers [PDF]

open access: yes, 2012
肿瘤标志物的有效检测对于恶性肿瘤的早期诊断、治疗观察和复发预测起着至关重要的作用。在临床应用中,单组分检测存在特异性不强、阳性率低等不足。因此,迫切需要发展多种标志物的联合检测技术以提高肿瘤诊断的准确性。流式微珠阵列技术(flowcytometricbeadarray,FCBA)又称液相芯片技术,是将溶液中的待检测物质通过生物分子间的特异性亲和反应结合在微米级的经光学编码的微珠上,利用流式细胞术对同一份微量样品中的多种待测组分同时进行快速、定性、定量分析的新型检测技术。目前 ...
高敏
core  

Allometric Scaling in Environmental DNA Concentration of Japanese Eel Anguilla japonica Confirmed Under Laboratory and Natural Conditions 日本鳗 (Anguilla japonica) 环境 DNA 浓度中的异速生长标度在实验室和自然条件下得到证实

open access: yesIntegrative Conservation, Volume 4, Issue 4, Page 675-685, December 2025.
We demonstrated that Anguilla japonica eDNA concentration was allometrically scaled with their body size in both the laboratory and riverine environments. Integrating body size allometry has the potential to improve population abundance estimates in the field, whereas further clarification is required for understanding eDNA production mechanisms ...
Toshiaki S. Jo   +2 more
wiley   +1 more source

探讨慢性心衰患者联合检测肌红蛋白和心型脂肪酸结合蛋白的临床价值

open access: yesZhongguo shiyan zhenduanxue, 2015
目的探讨慢性心衰患者联合检测肌红蛋白和心型脂肪酸结合蛋白的临床价值,结合临床表现为临床诊治提供依据。方法选择确诊为慢性心衰者共78例,设为研究组,另外配对选择可比性强的同期体检健康者的80例设为对照组,均检测心型脂肪酸结合蛋白和肌红蛋白浓度水平,综合分析结果。结果研究组患者的肌红蛋白和心型脂肪酸结合蛋白浓度水平检测结果均明显高于对照组,差异具有统计学意义 ...
罗成富
doaj  

联合检测HBV前S1抗原和核心抗原的临床意义 [PDF]

open access: yes, 2008
目的:探讨联合检测血清HBV前S1抗原(preS1)和核心抗原(HBcAg)(均为HBV核酸相关抗原,nucleic acids related antigen,HBV NRAg)的意义及临床价值。方法:采用ELISA法对393份HBsAg、HBV DNA双阳性的血清和612份HBsAg阴性血清进行HBV NRAg检测,所有标本均采用多区段巢式PCR确认阳性、阴性,采用荧光定量PCR法进行HBV DNA定量分析。结果:393份HBsAg、HBV DNA双阳性血清中,HBV NRAg阳性为382份 ...
周健   +7 more
core  

Advances in metals and metal hybrids‐based gas sensors and their applications

open access: yesRare Metals, Volume 44, Issue 12, Page 9363-9413, December 2025.
Graphical abstract Abstract As a kind of node on the Internet of Things, gas sensor is specifically utilized for detecting gaseous chemical species and humidity. Functioning as a kind of discrete electronic components, gas sensors have been extensively implemented in many fields, including agricultural production, public safety, healthcare activity ...
Danyao Qu   +7 more
wiley   +1 more source

GPC3联合AFP、CEA、CA199检测对肝细胞癌的临床诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 探讨GPC3联合AFP、CEA、CA199对肝细胞癌诊断的临床应用价值。方法 采集实验者外周血,离心分离血清,免疫化学发光法检测血清中AFP、CEA及CA199的水平;ELISA法检测血清中GPC3的水平。统计分析各组实验者血清标志物和GPC3的差异,计算联合检测的诊断效率。结果 肝细胞癌患者血清中GPC3、AFP、CEA及CA199的表达水平高于疾病对照组和健康对照组。血清GPC3、AFP、CEA及CA199联合检测的灵敏度、特异度及准确度均高于各项指标的单项检测。结论 ...
doaj  

人附睾蛋白4、糖类抗原125、D-二聚体的测定在卵巢癌诊断中的临床价值研究

open access: yesZhongguo shiyan zhenduanxue, 2021
目的探讨人附睾蛋白4、糖类抗原125、D-二聚体的测定在卵巢癌诊断中的临床价值。方法选择2016年6月至2019年6月期间于锦州市中心医院就诊的经病理活检确诊为卵巢癌的患者90例(卵巢癌组),另外选择同期于锦州市中心医院接受诊疗的112例卵巢良性肿瘤患者(良性组),再选择同期于我院接受体检的健康女性125例(对照组)。抽取3组纳入对象空腹状态下肘静脉血,HE4、CA125采用化学发光微粒子免疫反应法予以测定,D-D采用免疫比浊法予以测定。比较3组纳入对象血清CA125、HE4及D-D水平 ...
吕岩, 王瑚
doaj  

Expression and Clinical Significance of mTOR and PTEN in Non-small Cell Lung Cancer [PDF]

open access: yes, 2010
Background and objective It has been proved that mTOR was an important signal transduction molecular and protein kinase regulating cell growth and proliferation, and mTOR could activate the downstream protein effector. PTEN could negatively regulate mTOR
Liang WANG   +5 more
core  

Application of Circulating Tumor DNA in Precision Diagnosis and Treatment of Colorectal Cancer [PDF]

open access: yes
Colorectal cancer (CRC) is one of the most common malignant tumors recorded worldwide. This condition has high morbidity and mortality and seriously endangers people's health.
CAI Jidong   +5 more
core   +1 more source

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