Results 11 to 20 of about 12,489 (209)
SARS‐CoV‐2 infection as cause of in‐utero fetal death: regional multicenter cohort study
ABSTRACT Objective Placental infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can lead to placental insufficiency and in‐utero fetal death (IUFD). The objective of this study was to confirm and quantify the extent to which fetoplacental infection with SARS‐CoV‐2 is a cause of fetal death.
M. Nkobetchou +9 more
wiley +1 more source
ABSTRACT Objective Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vertical transmission has been investigated extensively. Recently, the World Health Organization (WHO) published strict criteria to classify the timing of mother‐to‐child transmission of SARS‐CoV‐2 into different categories.
R. Sevilla‐Montoya +23 more
wiley +1 more source
Abstract Aim To determine the effectiveness of a hydrophobic dressing (Cutimed Sorbact®) against a silver dressing (Aquacel® Ag Extra) in the level of colonization of chronic venous leg ulcers. The secondary endpoints are health‐related quality of life, level of pain, and time to complete healing.
Juan C. Morilla‐Herrera +9 more
wiley +1 more source
Abstract Background The molecular phenotype of circulating tumor cells (CTCs) was associated with clinical outcome of patients with breast cancer. CTCs isolated from patients with metastatic breast cancer (MBC) display a unique microRNA (miRNA) expression profile.
Weige Tan +11 more
wiley +1 more source
Amplification of Ovis aries papillomavirus type 2 DNA from an ovine cutaneous fibropapilloma
Seven of 60 Perendale sheep within a flock developed single or multiple exophytic masses on their distal hind limbs. A mass was excised from one sheep and histological evaluation revealed epidermal and mesenchymal proliferation, papillomavirus‐induced keratinocyte changes and marked keratohyalin clumping.
John S. Munday +2 more
wiley +1 more source
ABSTRACT Objectives First, to determine the incremental yield of whole‐genome sequencing (WGS) over quantitative fluorescence polymerase chain reaction (QF‐PCR)/chromosomal microarray analysis (CMA) with and without exome sequencing (ES) in fetuses, neonates and infants with a congenital anomaly that was or could have been detected on prenatal ...
N. Shreeve +6 more
wiley +1 more source
TIPE expression in gastric cancer and its clinical significance [PDF]
背景及意义:胃癌是严重危害人类健康的最常见的恶性肿瘤之一,发病率位居所有恶性肿瘤的第二位,死亡率列所有恶性肿瘤的第三位,目前临床上大多数患者确诊胃癌时已是中晚期,根治性手术仍然是胃癌的主要治疗方式,也是唯一有希望治愈胃癌的手段,但手术效果不佳,直接影响愈后。因此深入研究胃癌发生、发展的分子机制,可为胃癌早期诊断提供依据,同时也为临床治疗提供有效的靶点治疗,具有重要的临床意义。肿瘤坏死因子α诱导蛋白8(Tumornecrosisfactor-αinducedprotein-8,TIPE,TNFAIP8 ...
胡如意
core
【目的】探索一种利用随机引物聚合酶链反应指纹法技术进行变形链球菌基因分型的方法。【方法】利用变形链 球菌不同血清型标准株和通用引物5′-TGCCGAGCTG-3′, 研究了在不同条件下进行聚合酶链反应的结果, 寻找满意的聚合酶 链反应条件。【结果】找到了较为满意的聚合酶链反应条件:94 ℃ 30 s , 36 ℃ 30 s, 72 ℃ 1 min, 反应进行45 个循环。【结论】 随机引物聚合酶链反应指纹法技术在一定的控制条件下可用于变形链球菌的鉴定和分型。
陈 罕 +5 more
doaj
Identification of autoanti-B antibody produced by B blood group, a case report
目的 对1例罕见的B抗原特异性自身抗体标本进行鉴定分析。方法 采用经典试管法、吸收放散法、微柱凝胶法检测血型抗原及抗体。巯基试剂处理血浆、直接抗球蛋白分型鉴定抗体性质。序列特异引物引导的聚合酶链反应进行ABO基因分型,测序分析ABO基因1~7外显子核苷酸序列。结果 ABO血型正反定型不符,正定型B抗原4+,血浆与反定型B细胞凝集2+s,不规则抗体筛查阴性。吸收放散试验证实:存在特异性抗-B,抗体性质为IgM,4℃条件体外溶血试验阳性。SSP基因分型为B/O1;1 ...
Yuan ZHAO, Tongtong LI, Hongyu LIU
doaj +1 more source
The role of histone acetylation in Rheumatoid arthritis peripheral blood mononuclear cells [PDF]
研究背景类风湿关节炎(rheumatoidarthritis,RA)是一种常见的全身性自身免疫疾病,以慢性、进行性、侵袭性关节炎为主要临床表现。该病发病机制尚不明确,研究其发病机制对临床指导治疗具有极其深远的意义。组蛋白乙酰化在RA的发病机制中具有重要作用。组蛋白乙酰化是一种可逆的动态过程,主要由组蛋白乙酰转移酶(histoneacetylase,HATs)和组蛋白去乙酰化酶(histonedeacetylases,HDACs)协调修饰。既往研究中,Huber,L.C.等人的研究显示 ...
宋丽娜
core

