Results 11 to 20 of about 4,885 (152)

SARS‐CoV‐2 infection as cause of in‐utero fetal death: regional multicenter cohort study

Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 6, Page 867-874, December 2023., 2023
ABSTRACT Objective Placental infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can lead to placental insufficiency and in‐utero fetal death (IUFD). The objective of this study was to confirm and quantify the extent to which fetoplacental infection with SARS‐CoV‐2 is a cause of fetal death.
M. Nkobetchou, M. Leruez‐Ville, T. Guilleminot, N. Roux, G. Petrilli, F. Guimiot, M.‐H. Saint‐Frison, I. Deryabin, Y. Ville, V. Faure‐Bardon   +9 more
wiley   +1 more source

Evidence of possible SARS‐CoV‐2 vertical transmission according to World Health Organization criteria in asymptomatic pregnant women

Ultrasound in Obstetrics &Gynecology, Volume 58, Issue 6, Page 900-908, December 2021., 2021
ABSTRACT Objective Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vertical transmission has been investigated extensively. Recently, the World Health Organization (WHO) published strict criteria to classify the timing of mother‐to‐child transmission of SARS‐CoV‐2 into different categories.
R. Sevilla‐Montoya, A. Hidalgo‐Bravo, G. Estrada‐Gutiérrez, O. Villavicencio‐Carrisoza, M. Leon‐Juarez, I. Villegas‐Mota, S. Espino‐y‐Sosa, I. E. Monroy‐Muñoz, R. J. Martinez‐Portilla, L. C. Poon, J. A. Cardona‐Pérez, A. C. Helguera‐Repetto, Collaborators, L. D. Gonzalez‐García, C. D. Mora‐Vargas, P. Mateu‐Rogell, M. Rodriguez‐Bosch, I. Coronado‐Zarco, S. Acevedo‐Gallegos, M. Aguinaga‐Ríos, V. H. Ramirez‐Santes, M. A. Ortiz‐Ramirez, M. Valdes‐Flores, M. Cortes‐Bonilla   +23 more
wiley   +1 more source

Effectiveness of a hydrophobic dressing for microorganisms’ colonization of vascular ulcers: Protocol for a randomized controlled trial (CUCO‐UV Study) 疏水性敷料对血管溃疡中微生物定植的有效性:随机对照试验方案(CUCO‐UV研究)

Journal of Advanced Nursing, Volume 76, Issue 8, Page 2191-2197, August 2020., 2020
Abstract Aim To determine the effectiveness of a hydrophobic dressing (Cutimed Sorbact®) against a silver dressing (Aquacel® Ag Extra) in the level of colonization of chronic venous leg ulcers. The secondary endpoints are health‐related quality of life, level of pain, and time to complete healing.
Juan C. Morilla‐Herrera, José M. Morales‐Asencio, Alberto J. Gómez‐González, Antonio Díez‐De Los Ríos, Inmaculada Lupiáñez‐Pérez, Carlos Acosta‐Andrade, Marta Aranda‐Gallardo, Ana B. Moya‐Suárez, Shakira Kaknani‐Uttumchandani, Silvia García‐Mayor   +9 more
wiley   +1 more source

Incorporating MicroRNA into Molecular Phenotypes of Circulating Tumor Cells Enhances the Prognostic Accuracy for Patients with Metastatic Breast Cancer

The Oncologist, Volume 24, Issue 11, Page e1044-e1054, November 2019., 2019
Abstract Background The molecular phenotype of circulating tumor cells (CTCs) was associated with clinical outcome of patients with breast cancer. CTCs isolated from patients with metastatic breast cancer (MBC) display a unique microRNA (miRNA) expression profile.
Weige Tan, Gehao Liang, Xinhua Xie, Wenguo Jiang, Luyuan Tan, Andrew J. Sanders, Zihao Liu, Yun Ling, Wenjing Zhong, Zhenluan Tian, Wanyi Lin, Chang Gong   +11 more
wiley   +1 more source

Amplification of Ovis aries papillomavirus type 2 DNA from an ovine cutaneous fibropapilloma

Veterinary Dermatology, Volume 35, Issue 2, Page 226-229, April 2024.
Seven of 60 Perendale sheep within a flock developed single or multiple exophytic masses on their distal hind limbs. A mass was excised from one sheep and histological evaluation revealed epidermal and mesenchymal proliferation, papillomavirus‐induced keratinocyte changes and marked keratohyalin clumping.
John S. Munday, Hanna J. Klobukowska, Karen Nicholson   +2 more
wiley   +1 more source

Incremental yield of whole‐genome sequencing over chromosomal microarray analysis and exome sequencing for congenital anomalies in prenatal period and infancy: systematic review and meta‐analysis

Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 1, Page 15-23, January 2024.
ABSTRACT Objectives First, to determine the incremental yield of whole‐genome sequencing (WGS) over quantitative fluorescence polymerase chain reaction (QF‐PCR)/chromosomal microarray analysis (CMA) with and without exome sequencing (ES) in fetuses, neonates and infants with a congenital anomaly that was or could have been detected on prenatal ...
N. Shreeve, C. Sproule, K. W. Choy, Z. Dong, K. Gajewska‐Knapik, M. D. Kilby, F. Mone   +6 more
wiley   +1 more source

The role and mechanism of IL-33 in gout [PDF]

, 2016
摘要 研究目的：以MSU诱导的小鼠实验性急性痛风为痛风研究模型，来探讨IL-33在急性痛风中的作用及其机制。 研究方法和结果： 1.重组小鼠IL-33的原核表达以及纯化 GST-IL-33融合蛋白经过原核表达、纯化，去除GST标签等步骤，获得了较高纯度的的mrIL-33。 2.对急性痛风患者血清中IL-33的研究 通过收集临床急性痛风患者41例（男39例，女2例）年龄26～91岁，平均58.3岁和44例年龄、性别与之匹配的健康志愿者的血清标本，检测血清中IL-33的含量。结果显示急性痛风患者血清中IL ...
苏群
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Protein phosphatase 2A-B55δ enhances chemotherapy sensitivity of human hepatocellular carcinoma under the regulation of microRNA-133b [PDF]

, 2016
目的：原发性肝细胞癌(hepatocellularcarcinoma，HCC)是我国公共卫生关注的热点问题之一，寻找增强HCC化疗敏感性的有效干预靶点具有重要意义。蛋白磷酸酶2A(proteinphosphatase2A，PP2A)是重要的肿瘤抑制因子；PPP2R2D基因编码的PP2A-B55δ亚基参与细胞周期有丝分裂调控。我们前期研究验证了PPP2R2D基因3’-非翻译区(3’-untranslatedregion，3’UTR)的+15G>C多态性位点受微小RNA-133b(microRNA-133b，
庄群瑛
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Identification of hepatitis C or/and G virus RNA in one tube by reverse transcription nested polymerase chain reaction [PDF]

, 1998
目的庚型肝炎病毒（HgV）与丙型肝炎病毒（HCV）同属黄病毒科，且传播途径相似，重叠感染率高，本研究旨在建立一种同时检测HgV与HCV感染的方法。方法根据HCV与HgV的基因序列分别选取5’-uTr（HCV）与nS3（HgV）的两套引物，在同一管内进行逆转录-巢式聚合酶链反应，并初步应用于153例标本。结果该方法能同时检出HgV与HCV感染，扩增片段大小与设计相符。结论该方法简便特异，适用于临床检测Hepatitis C and G viruses belong to the flaviviridae ...
伊瑶, 夏宁, 苗季, 詹美云, 谭文杰, 邵丛郁, 陈刚   +6 more
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Studies of the regulatory mechanism on myocardial related genes of Rbm24 [PDF]

, 2015
实验目的 研究在心肌细胞分化和发育过程中，Rbm24蛋白发挥功能和产生的影响。寻找Rbm24结合的相关基因的不同水平的RNA，以及结合目的RNA后所发挥的功能，为降低Rbm24的表达导致扩张性心肌病等一系列心肌受损和功能紊乱相关疾病探究原因，寻找相关的信号通路，提供一定的实验及理论依据，为成功解决心脏疾病难题寻找重要的攻克点。 方法 通过Westernblot免疫印迹检测Rbm24和其他心肌相关蛋白在C2C12细胞分化中蛋白的表达情况 ...
杨康
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