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微生物与人体免疫系统的互动一直是生物医学研究的焦点。新一代测序发现不仅肠道,呼吸道也存在着微生物群,且肠-肺微生物群之间通过免疫细胞及其活性因子等形成了一个相互关联的网络。本综述旨在探讨肠道和肺部微生物群如何调节免疫应答,包括其在局部和全身免疫调节中的作用;同时,解析肠-肺轴之间的免疫联系,对深入理解微生物在免疫系统的作用及探索新的疾病诊疗策略具有重要临床意义。
张萌, 杨正飞
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Progress in Culturemics Research on Beneficial Intestinal Bacteria [PDF]
Gut microbes especially the beneficial ones play an important role in maintaining human health. At present, the research methods for intestinal microbes are mainly based on non-culture technologies such as metagenomics.
YU Xia, ZHAO Feiyan, SUN Zhihong
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Correlation of immune function: gut microbiota and radiation enteritis in patients with cervical cancer [PDF]
Objective To investigate the relationship of immune function and gut microbiota with radiation enteritis (RE) in patients with cervical cancer. Methods Clinical data of 80 patients with cervical cancer were retrospectively analyzed.
Jing Wenjiang, Chen Jiaqi, Luo Ruonan, Ma Wu
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Research progress on sugar substitutes and human health [PDF]
Sugar reduction and restriction have become one of the most urgent health demands as the number of obese people increases globally. Sugar substitutes (mainly classified into sugar alcohols, natural sweeteners, and artificial sweeteners) have been widely ...
Mengying QU +4 more
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Latest Research on the Neuroprotective Mechanism of Short-chain Fatty Acids in Stroke and Its Relation with Post-stroke Cognitive Impairment [PDF]
Post-stroke cognitive impairment is one of the common complications of stroke, seriously affecting patients' ability to perform activities of daily living.
LIU Huanhuan, LI Ruiqing, SU Kaiqi, YUAN Jie, LI Qi, FENG Xiaodong
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Progress in Understanding the Relationship between Diabetes and Host Intestinal Microbiota and Diet-Mediated Microbiota Regulation [PDF]
Diabetes is a metabolic disease characterized by insulin secretion disorder. When serious, it can cause various complications (cardiovascular and cerebrovascular diseases, cataract and other eye diseases, kidney disease and cancer), bringing a huge ...
WANG Danping, XU Jinzhao, ZHANG Xiaohang, NING Ke, LIU Ye, XU Yuanzhi, XIE Qinggang, XU Xiaoxi
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Novel Developments in the Relationship of Gut Microbiota and Immune Regulation with Childhood Asthma [PDF]
Bronchial asthma, commonly known as asthma, is a frequently seen chronic respiratory disease that seriously threatens human health. More than 300 million people have had asthma worldwide, and most of them are children. Epidemiological investigations have
CUI Tianyi, LIU Jiarui, LYU Bin, GAO Xiumei, ZHAO Xin
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肠道是动物机体重要的消化吸收器官,肠道微生物在宿主的免疫代谢、营养吸收、行为等方面起着十分重要的作用。因此,动物肠道微生物研究正成为动物生态学和保护生物学的热点领域。为了给爬行动物的健康及后续肠道微生物研究提供科学参考,综述了爬行动物肠道微生物的研究手段、分布特点和影响因素。研究表明,爬行动物肠道微生物具有区段差异性和易受寄主生殖状态、饮食、环境和行为等因素影响的特点,现阶段研究手段以高通量测序技术为主。
钟春英 1 +5 more
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Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases [PDF]
Ketogenic diets have been shown to play a role in some metabolic diseases and neurodegenerative diseases as a low-carbohydrate, high-fat diets supplemented with appropriate protein. Ketogenic diets have been proven effective, but the mechanisms of action
Jian LI +5 more
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川、滇、黔金丝猴(Rhinopithecus roxellana、Rh.bieti、Rh.brelichi)均为我国特有种,国家一级重点野生保护动物。作为典型的食叶动物,其肠道微生物组特性研究也备受学者关注。为探究川、滇、黔金丝猴肠道微生物组结构,促进金丝猴胃肠道健康及为相关疾病防控提供参考数据,以北京动物园管理处圈养的3种7只金丝猴为研究对象,采用16S rDNA测序及分析技术,开展相同圈养环境下3种金丝猴肠道微生物组差异研究。结果显示:圈养健康金丝猴肠道微生物组的优势菌门为厚壁菌门 ...
张媛媛 +7 more
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