Results 21 to 30 of about 4,781 (157)
野生动物学报, 2022 哺乳动物的肠道中存在庞大的微生物群落,这些微生物与宿主自身的消化吸收、能量代谢和免疫防御等生命活动息息相关。海南长臂猿(Nomascus hainanus)是世界上最濒危的灵长类动物之一,现存海南长臂猿种群小、分布范围狭窄、近亲繁殖隐患高,尚未摆脱物种灭绝风险,目前对该物种现存种群的肠道微生态研究匮乏。以海南热带雨林国家公园4个家庭群内的5只成年雄性海南长臂猿为研究对象,在旱季通过非损伤取样法及宏基因组学技术对采集到的粪便中的微生物进行测序分析和功能注释。结果表明 ...
李依蒙, 毕 玉, 金 崑
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Zhongguo youzhi, 2022 为了进一步开发与应用元宝枫籽油，研究了元宝枫籽油对高脂膳食小鼠脂代谢及肠道健康的影响。将60只小鼠分为空白组、模型组、元宝枫籽油高剂量组〔1 200 mg/(kg·d）〕和低剂量组〔600 mg/(kg·d）〕，连续灌胃60 d。实验结束后，测定小鼠生长状况、血脂水平、盲肠微环境指标和盲肠内容物短链脂肪酸及微生物菌群。结果表明：与模型组相比，元宝枫籽油高剂量组能显著降低小鼠体质量、腰围、Lee′s指数、腹腔脂肪质量，显著降低小鼠盲肠内容物中游离氨、氨态氮、硫化氢和pH，显著增加盲肠内容物中丁酸 ...
安玉红1，关天琪1，郭艳红1，李慧1,梁世康2，黄涛2 AN Yuhong1，GUAN Tianqi1，GUO Yanhong1，LI Hui1，LIANG Shikang2，HUANG Tao2
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Analysis of gut microbiota changes in alcoholic fatty liver disease in progression based on 16S rDNA sequencing technology [PDF]
Objective To analyze the changes of gut microbiota in the progression of alcoholic fatty liver disease(AFLD) using 16S rDNA sequencing technology, and to explore the possible mechanism of AFLD progression in mice.
DONG Xiaowei +5 more
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Ameliorative Effect of Hovenia dulcis Fruit Pedicel Polysaccharides on Alcohol-Induced Intestinal Injury in Mice Investigated Using 16S rRNA Sequencing and Metabolomics [PDF]
This study aimed to explore the ameliorative effect of Hovenia dulcis fruit pedicel polysaccharides (HDPs) on intestinal injury in alcohol-exposed mice.
ZHANG Yuchao, ZHU Sijie, LIU Liangyu, WANG Jianyun, ZHANG Jiaxin, SU Zexiong, CHEN Jiangyan, LIU Xudong
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野生动物学报, 2020 高原鼠兔和高原鼢鼠是青藏高原的两种优势小型哺乳动物，其肠道微生物在宿主高原适应性方面发挥着重要作用，同时，作为野生动物，它们的肠道微生物也可能携带抗生素抗性基因并将其传播给人类，造成抗生素药物失效。因此，对这两个物种肠道微生物组和抗生素抗性基因的研究十分重要。本研究通过16S rRNA基因测序，定量PCR等技术获得两物种肠道菌群特征并检测到了抗生素抗性基因。结果发现，在门水平上，高原鼢鼠肠道拟杆菌门（Bacteroidetes）的相对丰度更高；而高原鼠兔肠道厚壁菌门（Firmicutes）和放线菌门 ...
冯天舒 1 俞巧玲 1 周蕊 1 王逸洁 1 苏军虎 2 李欢 1 +1 more
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野生动物学报, 2021 动物肠道中寄生着数以亿计的微生物,参与到动物机体中如代谢和免疫等重要的生理过程中。然而,在粪便等复杂样本中包含着大量微生物,无法通过纯培养技术进行研究,无法评估样本中的微生物多样性。通过宏基因组学技术可以对微生物群总DNA进行分析,使其成为目前研究复杂样本微生物结构和功能的重要工具。并且伴随高通量测序技术和生物信息学的进步,对微生物的分析流程也在不断地被改进。本文比较了在宏基因组学中普遍应用的标志基因扩增子分析和全宏基因组分析,对宏基因组技术在几类野生脊椎动物肠道微生物领域中的应用进行综述 ...
赵宇卓 吴 尽 杨天雄 姚茂林 裴 欣 付蓝仪 刘学东
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Advances in the interaction between intestinal macrophages and the gut microbiota in intestinal diseases [PDF]
The human body harbors a vast array of microorganisms on its surface, with the intestine serving as the primary habitat. The gut microbiota comprises thousands of species of bacteria, viruses, fungi, and protozoa, forming a vast and dynamic microbial ...
CHEN Xiuqi +3 more
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Application potential of grain and oil processing by-products in research of microbial-oriented food [PDF]
, 2019 Hundreds of millions of bacteria adhere to human intestinal epithelium,which are the participants of human health and physiological functions,and also an important target covered by the concept of comprehensive health.So far,the supplementation of ...
CHEN Hong-juan +8 more
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Veterinary Dermatology, Volume 36, Issue 2, Page 148-158, April 2025.Background – Biofilm production by canine otitis externa (COE) pathogens and resistance development to multiple antimicrobials are commonly reported problems in veterinary practice. The use of adjuvants to disrupt biofilms may be a viable adjunctive therapy.
Bhumika F. Savaliya +3 more
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炎症性肠病合并非酒精性脂肪性肝病的经济负担及危险因素 [PDF]
, 2018 非酒精性脂肪性肝病(NAFLD)是一种影响约1/4普通人群的疾病,已成为我国及西方国家第一大慢性肝病,造成了巨大的医疗和经济负担。炎症性肠病(IBD)患者中,NAFLD的患病率估计高达40%,包括溃疡性结肠炎和克罗恩病。主要介绍IBD患者中合并NAFLD的现状与经济负担、危险因素评估,并对该类疾病进行总结与展望,以期为未来该领域的进一步研究奠定基础。陕西省科技攻关计划(2016SF-327);;陕西省普通高等学校优势学科建设项目(陕教位[2014 ...
冯巩 +5 more
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