Research progress in the relationship between gut microbiota metabolite trimethylamine N-oxide and ischemic stroke. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban缺血性脑卒中(ischemic stroke，IS)是一类严重危害人类健康的脑血管疾病。肠道菌群作为中间介质在大脑与肠道之间起到双向调节的关键作用。近年来，氧化三甲胺(trimethylamine N-oxide，TMAO)作为肠道菌群代谢产物在心血管疾病中受到广泛关注。高TMAO水平可能通过影响IS的危险因素如动脉粥样硬化、心房颤动、高血压和2型糖尿病增加IS发生风险。TMAO加剧IS患者神经功能的损伤，增加IS复发风险，而且是患者卒中后认知障碍(post-stroke cognitive ...
Fu Y, Hou X, Feng Z, Feng H, Li L.
europepmc +2 more sources
[Moxibustion Inhibits Postmenopausal Bone Loss by Regulating the Metabolism of Gut Microbiota-Related Serotonin]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue Ban目的 探究中医艾灸疗法对卵巢切除的雌激素缺乏小鼠骨代谢调控作用并探究其机制。 方法 将12 周龄雌性C57BL/6J小鼠随机分为假手术组（SHAM）、卵巢切除术组（OVX）、卵巢切除术合并广谱抗生素干预组（OVX-A）、卵巢切除术后艾灸干预组（OVX-M）及卵巢切除术后广谱抗生素干预同时艾灸组（OVX-A-M），每组5只。手术后4周，分别给予广谱抗生素和（或）艾灸干预4周后处死取材。采用Micro-CT检测各组小鼠股骨远端骨量并进行参数分析〔包括骨体积分数（bone volume/tissue ...
Huang X +6 more
europepmc +2 more sources
Time-limited diets and the gut microbiota in cardiometabolic disease. [PDF]
J Diabetes, 2022 Highlights Time‐specific diet is a novel nutritional approach to prevent and treat cardiometabolic disease. Feeding‐fasting cycles shape gut microbial composition and metabolite production. These alterations may play a causative role in driving the cardiometabolic benefits of intermittent fasting.
Ratiner K +3 more
europepmc +2 more sources
[Correlation between Gut Microbiota and Lung Cancer]. [PDF]
Zhongguo Fei Ai Za Zhi, 2020 基因-环境相互作用是癌症易感性和进展的基础。人体长期暴露于各种微生物所构成的微环境中并受其影响，如肠道菌群所构成的微环境。肺癌患者中某些肠道微生物的相对丰度与对照组相比存在显著差异。这些研究表明，肠道菌群可能通过某些途径与肺癌相关联。同时，与我们所暴露的外部环境相比，肠道菌群相对而言是易控制的环境变量，因为它们在个体内是高度可量化和相对稳定的。正如某些靶向肠道菌群的肺癌的诊断、干预、治疗的措施已在临床取得一定效果。在这篇综述中，我们主要讨论了肠道菌群通过某些途径，如通过调控代谢 ...
Teng J +4 more
europepmc +2 more sources
Effects of Aeriscardovia aeriphila on growth performance, antioxidant functions, immune responses, and gut microbiota in broiler chickens. [PDF]
J Zhejiang Univ Sci B, 2023 Farooq MZ, Wang X, Yan X.
europepmc +3 more sources
Modulating effects of Astragalus polysaccharide on immune disorders via gut microbiota and the TLR4/NF-κB pathway in rats with syndrome of dampness stagnancy due to spleen deficiency. [PDF]
J Zhejiang Univ Sci B, 2023 Zhao W +9 more
europepmc +2 more sources
Mechanisms of bariatric surgery for weight loss and diabetes remission 减重手术减轻体重和缓解糖尿病的机制
Journal of Diabetes, Volume 15, Issue 9, Page 736-752, September 2023., 2023 Highlights Controversial changes in intestinal hormones after bariatric surgery (BS) were summarized. The changes of signaling proteins involved in insulin resistance and the newly proposed changes in growth differentiation factor 15, exosomes, and extracellular vesicles after BS were elucidated.
Mengsha Yin +6 more
wiley +1 more source