Results 41 to 50 of about 1,012 (110)
Zhongguo shiyan zhenduanxue, 2020 目的本文探究64排螺旋CT评估肾癌病理分级的可行性,为临床应用提供理论依据。方法将2015年2月至2016年6月共纳入符合标准的透明细胞肾癌患者34例。经手术或肾穿刺活检确定病理分期。术前行64排螺旋CT检查。观察病灶形态学特征,有无瘤栓,以及影像学指征。结果经组织病理学分析可知,Ⅰ级患者有6例,Ⅱ级患者有14例,Ⅲ级患者有10例,Ⅳ级患者有4例。不同病理级别的患者的年龄、性别差异较小,无统计学意义(P>0.05)。不同病理学分级的癌灶最大径、囊变坏死、钙化、浸润情况及有无瘤栓存在明显差异(P0.05)。
喻骏, 崔喜民, 贾英军
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ICP-MS测定肾癌患者血清微量元素水平及其临床意义分析 [PDF]
, 2010 采用电感耦合等离子体质谱法(ICP-MS)对24例健康对照者、30例肾癌患者血清中多种微量元素的含量进行测定,探讨血清微量元素与肾肿瘤的关系。与健康对照组相比,肾癌患者血清中V、CO、nI、Mn、Cd的含量显著增高 ...
杭纬 +4 more
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Potential role of SUMO-specific proteases 1 in ferroptosis [PDF]
Objective·To explore the potential role of SUMO-specific protease 1 (SENP1) in ferroptosis.Methods·The Cancer Genome Atlas (TCGA) database was used to analyze the correlation between the expression levels of SENP1 and the ferroptosis-related genes, acyl ...
BAI Meng +5 more
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Integrated single-cell and transcriptome sequencing to construct a prognostic model of M2 macrophage-related genes in prostate cancer [PDF]
ObjectiveTo explore the prognostic value of M2 macrophage-related genes in prostate cancer (PCa), aiming to predict tumor prognosis more accurately and enable personalized treatment.Methods·RNA sequencing (RNA-seq) data of PCa were downloaded from The ...
FENG Chengling, HAN Bangmin, TANG Kairan
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Zhongguo shiyan zhenduanxue, 2018 目的测定vinculin在大肠癌及肾癌组织中的表达情况,探究其在大肠癌及肾癌发生发展中的意义。方法用二维液相色谱-质谱联用技术对20例DukesB期大肠癌患者的癌组织及癌旁组织、18例透明细胞肾癌患者的癌组织及癌旁组织中vinculin表达水平进行检测,并通过免疫印迹实验进一步验证。结果 vinculin在大肠癌组织中的表达水平低于其癌旁组织,相反,在肾癌组织中表达较其癌旁组织高。结论 vinculin在大肠癌及肾癌的发生发展中起一定作用。
郑岩 +5 more
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Zhongguo shiyan zhenduanxue, 2020 1临床资料患者男性,50岁,以"肉眼血尿2个月"为主诉入院。2个月前患者无明显诱因出现全程肉眼血尿,伴血凝块,不伴尿频、尿急、尿痛及左腰部疼痛。查体双侧肾区叩击痛阴性。全泌尿系CT提示:右肾缺如,右肾区可见高密度缝合线影,右肾区腰大肌前方(约腰3椎体水平)可见结节状增高影,边界欠清,大小约1.5cm×1.7cm。尿脱落细胞学及FISH均为阴性。既往曾因"右腰部疼痛3个月,检查发现右肾占位1天"于2016年6月17日入我院,彩超提示右肾上极皮质可见范围约7.3cm×6 ...
董晓波 +5 more
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MAPK4 Accelerates Progression of Cervical Squamous Cell Carcinoma by Positively Regulating SLC3A2 Expression [PDF]
ObjectiveTo explore the role of MAPK4 in cervical squamous cell carcinoma (CSCC) for the identification of candidate prognostic prediction biomarkers and molecular therapeutic targets.
Jing YU +4 more
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Zhongguo shiyan zhenduanxue, 2019 VHL综合征是一种可引起多种良恶性肿瘤的遗传性疾病,每36000人中就有一人罹患该病。该病是由VHL基因无法正常表达引起的。VHL基因是一种抑癌基因,定位于染色体3p25-26。本文阐述了关于VHL综合征相关肾透明细胞癌的诊断治疗方法。1 VHL综合征1.1 VHL综合征是一种由VHL抑癌基因的突变引起的累及多器官的显性遗传病,影响包括中枢神经系统、肾脏、胰腺、肾上腺及生殖系统 ...
玄磊 +4 more
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Zhongguo shiyan zhenduanxue, 2016 随着围手术期管理的不断改善、新型免疫抑制剂的广泛应用,器官移植患者的临床疗效得到了显著提高,存活寿命逐渐延长。然而受者长期服用免疫抑制剂,机体的免疫监视能力下降,肾移植术后肿瘤的发生率较普通人群高,国内主要以泌尿系肿瘤为主,特别是尿路上皮癌更为多见,然而肾透明细胞癌少有报道。原肾发生恶性肿瘤是肾移植术后的严重疾病,已经成为影响肾移植患者远期生存率的危险因素之一[1 ...
位海建 +4 more
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Exploring the role of methylation-driven gene IFFO1 in pancreatic adenocarcinoma diagnosis, prognosis and cellular functions [PDF]
Background and purpose: Abnormal DNA methylation is closely associated with the onset and progression of tumors. This study aimed to investigate the expression of intermediate filament family orphan 1 (IFFO1), a methylation-driven gene (MDG) in ...
XU Ziqi, HU Ruizhi, LI Junjian, WANG Hongxia, SANG Youzhou
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