Results 41 to 50 of about 17,837 (120)

Analysis of current status and influencing factors on quality of life in patients with spinal metastases (脊柱转移瘤患者生存质量现状及影响因素分析)

中西医结合护理
Objective To explore the status quo and influencing factors of quality of life in patients with spinal metastases. Methods From January 2024 to November 2024, 143 patients with spinal metastasis in Chongqing cancer hospital were selected by the ...
XIE Chunhua (谢春花), CHEN Ping (陈平), ZHANG Xiaojuan (张晓娟)   +2 more
doaj   +1 more source

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen, Zhihang Xu, Yiping Zou, Zhenlai Jiang, Yecheng Li, Taochen He, Hanlin Yin, Jiali Li, Yanfei An, Jiande Han, Yuqi Xie, Wei Gan, Yaolin Xu, Wenquan Wang, Junyi He, Haibo Wang, Wenchuan Wu, Zhenyu Ye, Wenhui Lou, Jihui Hao, Liang Liu, Jun Yu, Ning Pu   +22 more
wiley   +1 more source

Tumor‐infiltrating B cells participate in shaping the immunosuppressive microenvironment in solid tumors

International Journal of Cancer, Volume 158, Issue 5, Page 1156-1165, 1 March 2026.
Abstract Tumor‐infiltrating B cells (TIBs) exhibit dual roles in the tumor microenvironment (TME) of solid tumors. While they can enhance anti‐tumor immunity through antibody production and immune activation, certain subsets—such as regulatory B cells (Bregs) and immunosuppressive plasma cells—contribute to immune evasion by secreting inhibitory ...
Zhitong Li, Ziyang Shen, Yuxiang Sun, Pengcheng Zhu, Tongyan Liu, Rong Yin   +5 more
wiley   +1 more source

基于直线加速器的海马体保护性全脑放疗的剂量学优化

Fushe yanjiu yu fushe gongyi xuebao
本研究使用双弧容积旋转调强放射治疗（VMAT）技术，探寻海马体剂量最低的多叶准直器角度并分析其原因，为临床治疗计划提供参考。随机选择10例脑转移瘤行全脑放疗的患者，为每位患者制作多个不同对称多叶准直器角度组合的海马体保护性全脑放疗（HA-WBRT）计划。在满足计划靶区（PTV）和危及器官的剂量学要求的前提下限制海马体的剂量。分析这些计划靶区的适形性指数、均匀性指数、D2%、D98%、机器跳数、治疗时间等靶区参数和海马体、晶状体、眼球、视神经和视交叉等危及器官的剂量，来评估不同多叶准直器计划的优劣 ...
王 宇, 许 德颖, 刘 云峰, 于 亮
doaj   +1 more source

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

Med Research, Volume 2, Issue 1, Page 89-105, March 2026.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu, Aihetaimujiang Anwaier, Qintao Ge, Siqi Zhou, Xi Tian, Shuxuan Zhu, Guohai Shi, Yu Zhu, Dingwei Ye, Mierxiati Abudurexiti, Hailiang Zhang   +10 more
wiley   +1 more source

Multidisciplinary collaboration and nursing practice of bone marrow suppression combined with catheter-related bloodstream infection of implanted port in a patient undergoing chemotherapy for lung cancer (多学科协作模式下1例肺癌患者化疗后骨髓抑制合并输液港相关血流感染的护理实践)

中西医结合护理
This article summarized the multidisciplinary collaboration and nursing practice of bone marrow suppression combined with catheter-related bloodstream infection (CRBSI) of implanted port in a patient undergoing chemotherapy for lung cancer.
WEI Ya (魏雅), LI Siqin (李思琴), LIU Yeqing (刘叶清), YUAN Wei (袁维), PENG Wenjie (彭文洁), FU Jianghong (付江红)   +5 more
doaj   +1 more source

Engineering a Tumor‐Targeted MgH2@Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation

Rare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu, Ming Deng, Tao Ge, Li Xu, Xinnan Xu, Kaiqi Jin   +5 more
wiley   +1 more source

A qualitative study on the establishment and application experience of whole-process management nursing pathway for lymphoma patients by navigation nurses (导航护士对淋巴瘤患者全程管理护理路径建立及应用体验的质性研究)

中西医结合护理
Objective To understand the establishment and application experience of whole-course management nursing path for lymphoma patients by navigation nurses, and to provide reference for the construction of whole-course management for lymphoma patients ...
WANG Shijuan (王石娟), HUANG Silin (黄思霖), LI Min (李敏), LU Changyuan (卢昌媛), RAN Yuxian (冉玉仙), ZHANG Lifeng (张丽凤), LAO Yongcong (劳永聪)   +6 more
doaj   +1 more source

Ovarian Cancer and High Body‐Mass Index: A Global Burden of Disease Database Study From 1990 to 2021

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Excess adiposity has been recognized as a significant modifiable risk factor for ovarian cancer (OC), but the epidemiology of OC attributable to high BMI remain largely unknown. Methods Utilizing comprehensive data from the Global Burden of Disease 2021 study, this investigation quantifies the epidemiological impact of elevated body
Xiaolong Li, Guangming Fu, Zhongyu Liu, Jiwei Li, Dongyong Shan   +4 more
wiley   +1 more source

Research progress of pain catastrophizing in patients after surgical treatment of lung cancer (肺癌术后患者疼痛灾难化的研究进展)

中西医结合护理
This paper reviewed current research status of pain catastrophizing in patients with lung cancer after surgery, and summarized the concept, theoretical basis, assessment tools, epidemiological characteristics, influencing factors and management ...
BIAN Guanjun (边冠军), ZHANG Chunmei (张春梅), LIU Lifeng (刘丽峰)   +2 more
doaj   +1 more source