Results 11 to 20 of about 3,888 (160)

The link between obesity and insulin resistance among children: Effects of key metabolites. [PDF]

J Diabetes, 2023
Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Yan W, Wu S, Liu Q, Zheng Q, Gu W, Li X.
europepmc   +2 more sources

Use of basal insulin in the management of adults with type 2 diabetes: An Asia-Pacific evidence-based clinical practice guideline. [PDF]

J Diabetes, 2023
Highlights This is a systematic review‐based clinical practice guideline. After internal and external review, two strong recommendations, six conditional recommendations, and one qualifying statement were made for insulin‐naive adult patients with type 2 diabetes.
Ji L, Luo Y, Bee YM, Xia J, Nguyen KT, Zhao W, Chen L, Chan SP, Deerochanawong C, Lim S, Yabe D, McGill M, Suastika K, Li X, Kong APS, Chen W, Zhao Z, Xu C, Deodat M, Yao X.   +19 more
europepmc   +2 more sources

Effect of dipeptidyl peptidase-4 inhibitor on the progression of coronary artery disease evaluated by computed tomography in patients receiving insulin therapy for type 2 diabetes mellitus. [PDF]

J Diabetes, 2023
Highlights Preclinical data showed that dipeptidyl peptidase‐4 inhibitors (DPP‐4is) may prevent insulin‐induced atherosclerosis. In patients treated with insulin for type 2 diabetes who underwent ≥2 serial coronary computed tomography angiographies(CCTA), a new obstructive coronary artery disease (OCAD) was less developed on the follow‐up CCTA in those
Choi Y, Ko SH, Chang K, Yoo KD, Ihm SH.
europepmc   +2 more sources

Effectiveness, safety, initial optimal dose, and optimal maintenance dose range of basal insulin regimens for type 2 diabetes: A systematic review with meta-analysis. [PDF]

J Diabetes, 2023
Highlights This is a systematic review and meta‐analysis. MEDLINE, EMBASE, Web of Science, and the Cochrane Library were searched from January 2000 to February 2022. Among 11,163 citations retrieved, 35 publications met the pre‐planned criteria. The five basal insulins are effective for insulin‐naive adult patients with T2DM. Glargine U‐300, degludec U‐
Luo Y, Xia J, Zhao Z, Chang Y, Bee YM, Nguyen KT, Lim S, Yabe D, McGill M, Kong APS, Chan SP, Deodat M, Deerochanawong C, Suastika K, Xu C, Chen L, Chen W, Li X, Zhao W, Yao X, Ji L.   +20 more
europepmc   +2 more sources

Patient experiences of continuous glucose monitoring and sensor‐augmented insulin pump therapy for diabetes: A systematic review of qualitative studies 糖尿病患者接受连续血糖监测和传感器增强胰岛素泵治疗的体验:对定性研究的系统综述

Journal of Diabetes, Volume 15, Issue 12, Page 1048-1069, December 2023., 2023
Highlights We identified that CGM can increase motivation for self‐management and confidence in treatments. A supportive treating team may help to reduce the practical and psychological burden in patients with type 1 and type 2 diabetes. Abstract Aims Blood glucose control is central to the management of diabetes, and continuous glucose monitoring (CGM)
Patrizia Natale, Sharon Chen, Clara K. Chow, Ngai Wah Cheung, David Martinez‐Martin, Corinne Caillaud, Nicole Scholes‐Robertson, Ayano Kelly, Jonathan C. Craig, Giovanni Strippoli, Allison Jaure   +10 more
wiley   +1 more source

Early weight gain after diagnosis may have an impact on remission status in children with new‐onset type 1 diabetes mellitus 儿童新发1型糖尿病诊断后早期体重增加可能对缓解状态产生影响

Journal of Diabetes, Volume 15, Issue 12, Page 1011-1019, December 2023., 2023
Highlights Weight gain with insulin therapy in the early period may be negatively related to the occurrence and duration of remission by altering insulin sensitivity. Interventions to prevent rapid weight gain and conserve insulin sensitivity in the early stages of type 1 diabetes mellitus may be beneficial for the development and maintenance of ...
Dicle Canoruc Emet, Hande Nur Karavar, Onur Gozmen, Arife Aslan Agyar, Yağmur Ünsal, Merve Canturk, Pınar Cengiz, Dogus Vuralli, Z. Alev Ozon, E. Nazlı Gonc   +9 more
wiley   +1 more source

Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

Journal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding, Xuejuan Zhang, Dandan Xiao, Wenguang Chang   +3 more
wiley   +1 more source

Beta‐cell function in type 2 diabetes (T2DM): Can it be preserved or enhanced? 2型糖尿病患者的β细胞功能:能被保留或增强吗?

Journal of Diabetes, Volume 15, Issue 10, Page 817-837, October 2023., 2023
Highlights Type 2 diabetes mellitus (T2DM) is characterized by progressive loss of beta‐cell function and mass. Numerous mechanisms of beta‐cell failure are involved. Preservation and/or enhancement of beta‐cell function is of great importance in delaying the progression of T2DM and the burden of its complications. Accurate evaluation of the effects of
Laure Sayyed Kassem, Aman Rajpal, Margarita Victoria Barreiro, Faramarz Ismail‐Beigi   +3 more
wiley   +1 more source

Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels 韩国2型糖尿病患者谷氨酸升高与纤溶酶原水平升高有关

Journal of Diabetes, Volume 15, Issue 9, Page 777-786, September 2023., 2023
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee, Jeong Won Yeom, Ji Ho Yun, Han Byul Jang, Min‐Gyu Yoo, Hyo‐Jin Kim, Soo Kyung Koo, Hye‐Ja Lee   +7 more
wiley   +1 more source

Weight loss and metabolic benefits of bariatric surgery in China: A multicenter study 减重手术的减重和代谢获益:一项中国多中心研究

Journal of Diabetes, Volume 15, Issue 9, Page 787-798, September 2023., 2023
Highlights Laparoscopic sleeve gastrectomy and laparoscopic Roux‐en‐Y gastric bypass are effective for reducing weight and improving metabolic parameters in Chinese patients with obesity. These interventions resulted in improved glycemic control, as evidenced by decreased glycated hemoglobin levels, reduced insulin resistance, and improved ...
Wenhuan Feng, Zhiming Zhu, Xiaoying Li, Zhiguang Zhou, Shen Qu, Xitai Sun, Dalong Zhu   +6 more
wiley   +1 more source