Results 31 to 40 of about 4,450 (159)

胰腺囊腺癌10例诊断体会

open access: yesZhongguo shiyan zhenduanxue, 2014
胰腺囊腺癌是一种比较少见的消化系统恶性肿瘤,经多年临床统计分析,胰腺囊腺癌在胰腺恶性肿瘤中仅占1%[1,2],由于其起病隐匿在早期难于发现而使其生存率极低,且易与胰腺假性囊腺瘤混淆,造成误诊、误治。我院自1997年6月至2011年3月共收治的10例经手术和病理证实为胰腺囊腺癌的患者,报道如下。1病例资料本组收集自1997年6月至2011年3月共10例本院经手术后病理诊断为胰腺囊腺癌的患者,其中男性患者4例,
李鑫   +5 more
doaj  

A study about the impact of overpression of Oct4 and Sox2 gene on gastric cancer cell biology and oncology characteristics [PDF]

open access: yes, 2015
目的:通过构建过表达干细胞因子Oct4和Sox2的胃癌SGC7901细胞株,研究过表达干细胞因子Oct4和Sox2对SGC7901胃癌细胞干细胞特性、肿瘤学特性、及生物学特性的影响,并探讨Oct4及Sox2在肿瘤细胞中的作用机制。 方法:1.构建携带Sox2基因的重组质粒,慢病毒载体感染SGC7901-OCT4细胞株得到SGC7901-OCT4-SOX2稳转细胞株。2.利用荧光定量PCR、western–bloting检测过表达Oct4及Sox2的胃癌SGC7901细胞中胃癌干细胞标志基因表达情况。3 ...
李文鹏
core  

超声对胰腺癌的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2007
目的评价超声对胰腺癌的诊断及应用价值。方法回顾性分析2004年4月-2005年10月我院收治的胰腺癌患者,比较分析术前超声诊断与术中所见、术后病理学结果,并与CT结果对照。结果63例经临床、术中所见或术后病理证实的胰腺癌患者中胰头癌45例(71.5%)、胰体尾癌12例(19.0%)、弥漫性胰腺癌6例(9.5%),术前行超声确诊或提示本病者54例(85.7%),误诊6例(9.5%),漏诊3例(4.7%)。结论超声对胰腺癌的检出率高,是一种无创、便捷的检查方法之一。
焦丹   +4 more
doaj  

CFTR及SPINK1蛋白在慢性胰腺炎及胰腺癌中的表达及其意义

open access: yesZhongguo shiyan zhenduanxue, 2011
目的探讨囊性纤维化跨膜转运调节因子(cystic fibrosis transmembrane conductance regulator,CFTR)及丝氨酸蛋白酶抑制剂Kazal 1型(Serine protease inhibitor Kazal type 1,SPINK1)在慢性胰腺炎及胰腺癌发病中的表达及其意义,为慢性胰腺炎及胰腺癌的早期诊断及预防提供实验依据,进而从基因水平上另辟新径。方法收集吉林大学第一医院病理科及白求恩医学院病理系存档的正常胰腺组织10例,慢性胰腺炎20例,胰腺癌30例 ...
张敏   +5 more
doaj  

BAG Family Gene and Its Relationship with Lung Adenocarcinoma Susceptibility [PDF]

open access: yes, 2010
Background and objective BAG genes (Bcl-2-associated athanogene) belong to a recently discovered multifunctional anti-apoptosis gene family that regulate various physiological processes which include apoptosis, tumorigenesis, neural differentiation ...
Heng WU   +9 more
core  

Clinical significance of Twist, Bmi-1 and E-cadherin expression in Cervical Intraepithelial Neoplasia and Early Stage Cervical Cancer [PDF]

open access: yes, 2015
目的:研究Twist/Bmi-1/E-cadherin蛋白在早期宫颈癌组织、宫颈上皮内瘤变(CIN)组织与正常宫颈组织中的表达水平,探讨Twist/Bmi-1/E-cadherin在早期宫颈癌不同病变组织中表达的生物学意义,对宫颈癌患者预后的影响以及这三者之间的相关性。 方法:收集2009年7月—2013年10月在厦门大学附属中山医院手术切除的64例宫颈癌,41例CIN组织,12例正常宫颈组织石蜡标本,运用Elivision免疫组化法检测Twist/Bmi-1/E-cadherin在宫颈癌组织 ...
丁娅妮
core  

Research progress on medical imaging-based artificial intelligence in precision diagnosis and treatment of pancreatic cancer [PDF]

open access: yes
Pancreatic cancer is a highly malignant tumor of the digestive tract, and its precision diagnosis and treatment is a major challenge in clinical practice.
Zhu Lubing, Wang Jianhua
core   +1 more source

New advances in basic research, clinical diagnosis and treatment of pancreatic cancer in 2024 [PDF]

open access: yes
Pancreatic cancer is a highly malignant tumor, and its incidence rate has been slowly increasing since 2000. Although the improvement of diagnosis and treatment has led to an increase in the five-year survival rate of pancreatic cancer compared to 50 ...
WANG Ting, QIN Yi, XU Xiaowu, YU Xianjun
core   +1 more source

High expression of COUP - TF2 in bladder cancer and its role in tumor microenvironment [PDF]

open access: yes, 2017
目的 血管在肿瘤的发生和发展中扮演着必不可少的重要角色。目前在胰腺癌、乳腺癌等多种动物模型当中,都发现鸡卵清蛋白上游启动子转录因子2(ChickenOvalbuminUpstreamPromoterTranscriptionFactor2,COUP-TF2)表现出促进肿瘤的发展和转移,并促进肿瘤中血管的生成。但是在膀胱癌中还没有研究。因此,我们这个研究的目的是分析COUP-TF2蛋白在人膀胱癌组织中的表达,并评估其与肿瘤临床病理特征的关系,以及研究肿瘤微环境对于血管内皮细胞的影响 ...
王明山
core  

An exploratory study of INPP4B, a biomarker of gemcitabine chemoresistance in pancreatic cancer [PDF]

open access: yes
Background and purpose: Pancreatic cancer is a highly aggressive solid tumor of the digestive system, with radical resection being unfeasible in approximately 80% of patients due to the absence of specific clinical manifestations in the early stages. The
REN Jiaqiang, WU Shuai, SU Tong, LI Jie, HAN Liang, WU Zheng
core   +1 more source

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