Zhongshan Daxue xuebao. Yixue kexue ban, 1989 用人新鲜胰腺癌组织免疫BALB/c小鼠,取脾细胞与小鼠骨髓瘤细胞Sp2/0-Agl4融合,获得了分泌抗人胰腺癌单克隆抗体的杂交瘤细胞株。本文重点报道以ABC免疫组织化学法检查YPC1单克隆抗体与人正常组织和肿瘤组织的反应性。结果表明YPC1单克隆抗体与16例被检测的胰腺癌组织发生反应。其中9例(56.3％)呈强阳性反应,与23种正常组织中的10种(43.5％)以及19种非胰腺肿瘤中的8种(42.1％)有不同程度的交叉反应,但多数反应较弱。本研究提示以新鲜人体肿瘤组织作为免疫原制备单克隆抗体是简便可行的 ...
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A modified clinically relevant post-operative pancreatic fistula risk evaluation model based on ultrasound shear wave elastography: a prospective study [PDF]
, 2023 Objective·To modify previous clinically relevant post-operative pancreatic fistula (CR-POPF) risk evaluation models with quantitative evaluation of pancreatic tissue stiffness by ultrasound shear wave elastography (SWE).Methods·In this prospective study,
DONG Yi +6 more
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Leading research progress and prospect of antibody-drug conjugate in pancreatic cancer in 2022 [PDF]
, 2023 Pancreatic cancer is a type of malignant tumor with high incidence and low survival rate. It is urgent to develop novel and efficient therapeutic means for patients lacking surgical indications and patients with poor effects of radiotherapy and ...
ZENG Cheng, ZHANG Jian
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Updates on precision medicine of pancreatic neuroendocrine tumor [PDF]
, 2023 Since the concept of precision medicine proposed in 2011, the treatment of solid tumors has entered era of precision medicine led by gene testing. As a rare tumor, the incidence rate of pancreatic neuroendocrine tumor (PanNET) is increasing gradually. In
GAO Heli, XU Jin, CHEN Jie, YU Xianjun
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Best Evidence Summary for Perioperative Blood Glucose Management in Patients Undergoing Pancreatectomy [PDF]
, 2022 BackgroundBlood glucose disorder is a common perioperative problem in patients with pancreatectomy. However, current perioperative blood glucose management for pancreatic resection patients in China is mostly based on experience and lack of evidence ...
CUI Lei, LIU Linglong, WANG Jianjian, YU Huiping, SUN Qingmei, MIAO Yi, FANG Xiaoping
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Research progress on the mechanism of organ-specific lung metastasis in pancreatic cancer [PDF]
, 2023 Pancreatic cancer is a highly malignant tumor of the digestive system. Due to the non-specific clinical symptoms in the early stage, its early diagnosis is very difficult.
YUE Ming, WANG Liwei, CUI Jiujie
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Clinical Featuresof IgG4-related Disease [PDF]
, 2022 BackgroundIgG4-related disease (IgG4-RD) is a rare fibro-inflammatory disease, which is prone to missed diagnosis or misdiagnosis due to nonspecific clinical manifestations.ObjectiveTo analyze the clinical characteristics of IgG4-related disease (IgG4-RD)
DING Hang, LIU Yuan, ZHANG Lianfeng, ZHOU Lin
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The research on FBW7 gene enhances antitumor effect of paclitaxel on pancreatic cancer through GSDME-mediated pyroptosis [PDF]
, 2023 Background and purpose: Pancreatic cancer is a highly malignant disease. Most patients are in advanced stage upon diagnosis. Systemic chemotherapy is an important treatment method, but the chemotherapy drug resistance to tumors brings many problems to ...
JIA Yuming, YE Zeng, DENG Yanli, LI Shengchao, ZHANG Zhilei, WANG Chao, XU Xiaowu, QIN Yi, PENG Li
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Progress of magnetic iron oxide nanoparticles in targeted diagnosis and treatment of pancreatic cancer [PDF]
Pancreatic cancer has a very poor prognosis. Early diagnosis and treatment are especially critical for improving its prognosis. Nanotechnology has been widely used in the diagnosis and treatment of pancreatic cancer. Relying on the unique physicochemical
REN Jiaqiang, WU Shuai, MO Jiantao, ZHOU Cancan, HAN Liang, WU Zheng
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Clinical value analysis of simple resection of pancreatic solid pseudopapillary tumor [PDF]
Objective To explore the clinical application value of simple resection in the treatment of pancreatic solid pseudopapillary tumor(SPT). Methods Retrospective analysis of clinical and follow-up data of pancreatic SPT patients who underwent simple ...
GUO Yujie, TANG Ying, GU Jichun, YANG Feng, LIU Huaye, JIN Chen, FU Deliang, Li Ji
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