Results 71 to 80 of about 1,152 (141)
Zhongguo shiyan zhenduanxue, 2021 葛根素(7,4’-二羟基-8-C-葡萄糖基异黄酮)是从多年生豆科植物葛根中提取的异黄酮[1-2]。多年来,它在我国传统医学中被广泛应用于心血管疾病的临床治疗,包括心肌梗塞、脑缺血、心绞痛和高血压。葛根素对心脏功能有保护作用,防止缺血再灌注损伤,改善心肌代谢和减少梗塞面积。已有学者发现,葛根素可以通过减少活性氧的产生、避免线粒体膜电位的崩溃、减轻后续细胞凋亡来保护心肌细胞免受缺血再灌注损伤[3],但关于葛根素对老年大鼠心肌细胞氧化应激的影响尚无报道 ...
宋福成 +4 more
doaj
Dexmedetomidine exerts its protective effect on cerebral ischemia reperfusion injury in mice by inhibiting ferroptosis. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2022 Hu M +6 more
europepmc +1 more source
An immunoblotting test on rapid determination of bioactive astragaloside Ⅳ of traditional Chinese medicine [PDF]
, 2011 黄芪甲苷（astragalosideⅣ，AsⅣ）是黄芪药理活性的主要成分之一，属于皂苷类化合物，常作为评价黄芪药材及其制剂质量优劣的标准。现代医学研究表明，黄芪甲苷具有免疫调节、器官保护、降血糖、抗衰老、抗病毒等广泛的药理作用，具有较好的新药开发前景。 本研究的目的是应用本实验室筛选的抗AsⅣ的杂交瘤细胞株生产的单克隆抗体，建立一种以聚醚砜（PES）膜为载体的免疫印迹法，对黄芪药材中的AsⅣ进行快速检识和定量分析。 本研究内容主要包括抗AsⅣ单克隆抗体的生产和鉴定、基于该单克隆抗体的免疫印迹法的建立 ...
乔芳芳
core
Recent Advances on Active Components and Functional Properties of Chinese Yam [PDF]
Yam as a medicinal and edible resource plant, is abundant in bioactive compounds including polysaccharides, polyphenols, allantoin, and saponins, these constituents endow yam with diverse functional properties, such as antioxidant, anti-diabetic, anti ...
Baodang GUO +6 more
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, 2018 目的考察注射用奥扎格雷钠与0.9%生理盐水、5%葡萄糖溶液和5%果糖溶液配伍稳定性。方法使用0.9%生理盐水、5%葡萄糖溶液和5%果糖溶液3种临床常用大输液分别和注射用奥扎格雷钠配伍后,25℃恒温水浴保存,并分别在0、1、2、4、6、10h观察溶液外观、澄明度、pH计测定溶液pH值、HPLC测定奥扎格雷钠含量。结果注射用奥扎格雷钠与0.9%生理盐水、5%葡萄糖溶液和5%果糖溶液配伍放置10h后,溶液外观、澄明度、pH值均未发生改变;奥扎格雷钠在3种配伍溶液中稳定性良好,在10h内药物含量未出现下降 ...
伊丽
core
Research progress in mitochondrial dynamics-related proteins and ischemic stroke [PDF]
Ischemic stroke is a common acute cerebrovascular disease in clinical practice， which poses a severe threat to human health. In recent years， with deepening understanding of ischemic stroke， significant progress has been made in the diagnosis and ...
Li Tingting, Wang Qinpeng, Liu Xiaoqing, Cai Ke, Wei Yangyang, Liang Cheng
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, 2018 目的研究13-甲基十四烷酸（13-methyltetradecanoic acid, 13-MTD）对脑缺血后脑水肿的影响及其机制。方法线栓法制备大鼠大脑中动脉闭塞模型,于插入栓线前30 min分别尾静脉注射13-MTD 40、80、120 mg·kg-1（M40、M80、M120）,阴性对照组给予等体积脂质体。于缺血6、12、24 h,以Longa神经功能缺失评分观察神经功能缺失症状;TTC染色观察脑梗死体积大小;AutoCAD图像分析软件计算脑水肿程度;脑干湿重测定脑含水量;伊文思蓝（EB ...
冯晓, 张文荣, 陈世妹
core
Research progress in hypothermia-induced RBM3 in ischemia-reperfusion injury of various organs [PDF]
Ischemia-reperfusion injury （IRI） is a complex hemodynamic disorder with high mortality rates and limited treatment options. Mild hypothermia is a widely-accepted treatment method for alleviating ischemic and hypoxic injury， especially in the study of ...
Sun Luxuan, Dang Xiaoping, Sun Zijian
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, 2018 钱林超认为高血压发病与情志刺激、饮食劳倦等密切相关,肝郁、肝火与痰饮是高血压病的三大主要病因;其病机可归纳为肝郁化火、水饮内停;在临床上则以疏肝清热利水为主立法组方 ...
杜婷 +4 more
core
[Forsythiaside B inhibits cerebral ischemia/reperfusion-induced oxidative stress injury in mice via the AMPK/DAF-16/FOXO3 pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2023 Chen X +8 more
europepmc +1 more source