Results 21 to 30 of about 16,503 (167)
SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis
Summary The stress‐responsive hormone abscisic acid (ABA) is known for its inhibitory effects on various physiological processes, including seed germination, often resulting in energy deprivation. Interestingly, ABA‐induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a functional interplay between ABA and sugar ...
Xueyi Xue +3 more
wiley +1 more source
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu +13 more
wiley +1 more source
We profiled nutritional and physiological markers in captive sifakas, endangered primates from Madagascar, managed in expansive, non‐native forest enclosures. Variation in many markers reflects freely foraged diets and the energy required to maintain homeostasis under more naturalistic conditions.
Lydia K. Greene +5 more
wiley +1 more source
The Genome of Phoebe zhennan (Lauraceae) and Comparative Genomics of Phoebe 楠木(樟科)基因组与楠属植物比较基因组学研究
Phoebe zhennan is a Chinese endemic and valuable timber species of Phoebe (Lauraceae). We present a chromosome‐level genome assembly of P. zhennan. Our research provides novel insights into the genome evolution of Phoebe, including whole‐genome duplication, phylogenetic relationships of magnoliids, and key MYB regulatory genes involved in lignin ...
Mao Yameng +3 more
wiley +1 more source
Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman +33 more
wiley +1 more source
Summary Repetitive DNA is a feature of all organisms, ranging from archaea and plants to humans. DNA repeats can be seen both in coding and in noncoding regions of the genome. Due to the recurring nature of the sequences, simple DNA repeats tend to be more prone to errors during replication and repair, resulting in variability in their unit length ...
Sridevi Sureshkumar +3 more
wiley +1 more source
Metaproteomic study of marine phytoplankton blooms [PDF]
浮游植物是海洋初级生产力的主要贡献者,也是海洋食物链的重要组成,在海洋碳循环、生态系统维持和全球气候调节中起着重要作用。浮游植物藻华,特别是高频发生的甲藻和硅藻藻华,深刻地影响着海洋生态系统、全球气候以及人类健康。目前在浮游植物藻华形成的生态学和海洋学机制方面开展了大量工作,但我们对藻华形成的分子机制知之甚少。 本论文将宏蛋白质组学理念和方法应用于海洋浮游植物藻华研究,结合生物信息学分析手段,建立了海洋浮游植物藻华宏蛋白质组学研究方法,比较研究了藻华爆发区与非藻华区 ...
张浩
core
目的应用蛋白质组学相关技术筛选多发性骨髓瘤(MM)患者尿液中差异表达的蛋白质,寻找与MM诊断相关的疾病标志物。方法收集MM组、疾病对照组(肾脏疾病)、健康对照组尿液各8例,TCA沉淀法提取尿液蛋白质后建立双向凝胶电泳图谱;Image Master软件筛选差异蛋白质;利用MALDI-TOF-MS获得肽质量指纹图谱,通过Mas-cot软件进行数据库搜索,得到蛋白质鉴定结果。结果筛选出57个差异蛋白点,43个在MM组上调,14个下调。对其中30个差异蛋白点进行分析,鉴定出甘露聚糖结合凝集素相关蛋白19 ...
房亚哲 +7 more
doaj
AP-MS-based quantitative proteomics of protein interaction dynamics of P-TEFb regulation in HIV-1 gene transcription elongation [PDF]
艾滋病是由人类免疫缺陷病毒(Humanimmunodeficiencyvirus,HIV)感染引起的获得性免疫缺陷综合症(Acquiredimmunodeficiencysyndrome,AIDS),是一种以全身免疫系统严重损害为特征的严重传染性疾病。2008年法国科学家FrançoiseBarré-Sinoussi和LucMontagnier因发现HIV病毒及其病理获得了诺贝尔生理与医学奖。艾滋病已经夺取了全球几千万人的生命,并且现在还有四千多万的携带者 ...
何耀辉
core
Intragenic PNPLA1 duplication in Labrador retrievers with nonepidermolytic ichthyosis
Background – Ichthyoses represent a heterogeneous group of cornification disorders characterised by epidermal scaling. Objectives – To describe the clinical, histopathological and genetic analysis of a Labrador retriever with nonepidermolytic ichthyosis, and the results of a Labrador retriever population screening for a newly detected PNPLA1 genomic ...
Stefan J. Rietmann +7 more
wiley +1 more source

