Results 41 to 50 of about 70,351 (171)
ABSTRACT AI‐generated images have become so good in recent years that individuals often cannot distinguish them from ‘real’ images. This development, combined with the rapid spread of AI‐generated content online, creates a series of societal risks. Watermarking, a technique that involves embedding information within the content to indicate their AI ...
Bram Rijsbosch +2 more
wiley +1 more source
目的探讨β连环素(β-catenin)和MMP-2在非小细胞肺癌中的表达及意义。方法采用免疫组织化学方法检测39例肺癌组织及8例正常对照肺组织中β-catenin和MMP-2的表达,并结合临床和病理资料进行分析。结果 1.β-catenin和MMP-2在非小细胞肺癌组织中的胞质表达明显高于对照组,差异具有显著性 ...
孔康宝, 李光虎, 杨波, 崔永生
doaj
Effects of ApoE Isoforms Expression on Brain ApoE Lipidation and Amyloid-β Accumulation [PDF]
在编码人三种不同apoE蛋白亚型(E2、E3和E4)的APOE等位基因(ε2、ε3和ε4)中,APOEε4等位基因是阿尔茨海默病(Alzheimer’sdisease,AD)最重要的遗传风险因子,APOEε2等位基因则具有保护作用。鉴于apoE蛋白亚型对基于调节apoE蛋白表达的AD治疗可能会有不同的影响,我们通过在人APOE基因定位替换(Targetedreplacement,TR)小鼠脑中过表达不同的人apoE亚型,研究脑中表达不同apoE亚型对apoE脂化和β-淀粉样蛋白(Amyloid-β,Aβ)
胡进
core
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon +5 more
wiley +1 more source
Questa è una mini opera filosofico-scientifica che unisce riflessione e descrizione per esplorare l’origine, l’evoluzione e il destino dell’universo. Nasce dal desiderio di coniugare la profondità lirica della filosofia con la concretezza descrittiva della fisica, proponendo una nuova visione: l’universo non come frutto di perfezione, ma come ...
openaire +3 more sources
Survivin和Caspas3在侧向发育型大肠肿瘤中的表达
目的研究凋亡相关基因Survivin和Caspase3蛋白在侧向发育型大肠肿瘤(LST)中的表达。方法应用免疫组织化学方法检测良性LST、大肠腺瘤、大肠腺癌及其正常黏膜组织中Survivin和Caspase3的蛋白表达。结果 Sur-vivin在大肠腺癌(61.9%)高表达,良性LST(21.7%)和大肠腺瘤(20.6%)表达降低,而在正常黏膜组织不表达。Cas-pase3在正常黏膜高表达(90.9%),在良性LST(60.9%)和大肠腺瘤(64.7%)表达降低,在大肠腺癌(42.9%)低表达 ...
吴晓冬 +5 more
doaj
Research on Mechanisms of Urinary Bladder Mesenchymal Stem Cells Promote Cell Growth and Migration of Urothelial Carcinoma Cells Line 5637 [PDF]
目的:初步研究膀胱间充质干细胞促进膀胱癌生长及迁移的机制。方法:1.体外分离、培养并鉴定膀胱间充质干细胞;2.在体外实验中,以WST-1测定膀胱间充质干细胞培养上清液对于膀胱癌细胞生长的影响,并以划痕实验测定膀胱间充质干细胞培养上清液对于膀胱癌细胞迁移能力的影响;3.在动物模型中测定膀胱间充质干细胞对于膀胱癌细胞生长和迁移能力的影响;4.以WESTERN-BLOT检测相关信号通路关键蛋白表达的变化以研究膀胱间充质干细胞促进膀胱癌生长及迁移的机制:结果:1.膀胱间充质干细胞表达CD105 ...
佟智超
core
ABSTRACT f–f electronic transitions of rare‐earth elements typically exhibit unique physicochemical properties that benefit the photocatalytic performance of the catalysts containing the elements. Although conventional rare‐earth metal oxides or single‐atom doping in semiconductors have been extensively studied, the construction of heterojunction ...
Yang‐Sen Xu +6 more
wiley +1 more source
目的探讨Survivin和Ang2在人乳腺癌组织中的表达及其在淋巴转移中的作用。方法2060例乳腺癌组织,应用免疫组织化学S-P法检测Survivin和Ang2在乳腺癌组织中的表达情况,RT-PCR检测Survivin及VEGF-CmRNA的表达。结果2060例乳腺癌组织中Survivin和Ang2的表达阳性率分别为85.0%和73.3%,Survivin阳性表达组中Ang2的表达为74.5%(35/51),Survivin阴性表达组中Ang2的表达为66.7%(6/9),经直线相关分析 ...
李湘奇
doaj
Expression of IRG47 and Generation of Rabbit Polyclonal Antibody Against IRG47 [PDF]
IRG(Immunity-relatedGTPases)是干扰素γ诱导的免疫相关GTP蛋白,最先在脊椎动物中被发现。IRG蛋白在调节细胞内的病原体先天的抵抗力有着很重要的作用。在动物感染了细菌、原生动物和病毒的时候或者干扰素诱导,IRG蛋白表达量会升高。IRG蛋白在老鼠、兔子、狗、斑马鱼和人中都有表达。其中已经有研究表明,老鼠IRG蛋白在抵抗病原体和细菌作用上起到很重要的作用。IRG47属于IRG蛋白家族成员,但IRG47蛋白的性质和功能还没有被研究。 本文构建了IRG47的表达载体 ...
赵小敏
core

