Results 11 to 20 of about 5,409 (163)
血管性认知障碍患者往往伴有睡眠障碍,睡眠的紊乱进一步降低了患者的生活质量,增加了其脑血管事件的风险,也加重了照料者的负担。有效治疗患者的睡眠障碍不仅可以改善其生活质量,对患者的认知及功能康复也有积极影响。本文对血管性认知障碍患者常见的睡眠紊乱进行综述,着重阐述了睡眠障碍非药物治疗方面的研究成果,并对这些治疗方法未来的研究方向以及在血管性认知障碍患者中的应用前景进行了探讨。 Abstract: Patients of vascular cognitive impairment often ...
张心怡, 陈楚歆, 董建宇, 张宁, 王春雪
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沙库巴曲缬沙坦致认知障碍的风险分析-基于美国FDA不良事件报告系统(FAERS)数据库的研究 [PDF]
目的评价沙库巴曲缬沙坦致认知障碍的风险。方法根据medDRA术语标准,将认知障碍首选术语分为广义及狭义两个类别。以各首选术语为条件,检索美国FDA不良事件报告系统(FAERS)数据库2015年7月至2019年3月期间的不良事件报告,采用报告比值比(ROR)法,评价沙库巴曲缬沙坦与认知障碍的关系,并通过比较沙库巴曲缬沙坦与其临床试验期间对照药品依那普利的ROR值,比较两者在真实世界应用中致认知障碍风险的大小。结果共检索到沙库巴曲缬沙坦致认知障碍不良事件2 059份,其中广义认知障碍相关的不良事件1 ...
傅芳, 刘弋戈, 肖洁, 陈聪琴
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Latest Research on the Neuroprotective Mechanism of Short-chain Fatty Acids in Stroke and Its Relation with Post-stroke Cognitive Impairment [PDF]
Post-stroke cognitive impairment is one of the common complications of stroke, seriously affecting patients' ability to perform activities of daily living.
LIU Huanhuan, LI Ruiqing, SU Kaiqi, YUAN Jie, LI Qi, FENG Xiaodong
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Highlights The optimal blood pressure (BP) target in patients with type 2 diabetes mellitus (T2DM) for the management of cognitive decline remains unknown. The Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study was designed to determine whether intensive BP treatment (systolic BP <120 mm Hg) reduces risk of dementia and mild cognitive ...
The BPROAD Study Group +18 more
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This paper expounds the concepts of Traditional Chinese Medicine (TCM) characteristic nursing and post-stroke cognitive impairment, analyzes the etiology and pathogenesis of post-stroke cognitive impairment, reviews the application status of TCM ...
LI Wenya (李文雅) +3 more
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Graphical Abstract: Abstract Through the application of the Douglas Fir Group's transdisciplinary framework, this study investigated how three levels of mutually dependent influence (i.e., the micro level of social action and interaction, meso level of sociocultural institutions and communities, and macro level of ideological structures) operate across
Yuan Lu, Chuanren Ke
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Prevalence and Distribution Trends of Mild Cognitive Impairment among Chinese Older Adults:a Meta-analysis [PDF]
BackgroundMild cognitive impairment (MCI) has become a major disorder affecting the quality of life of Chinese older adults, a rapidly increasing population.
SHI Luping, YAO Shuihong, WANG Wei
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目的探讨老年人全麻史与轻度认知障碍(MCI)患病的关联性,并分析体智锻炼对这一关联性的影响,为早期预防和及时干预MCI提供新思路。方法基于湖北老年记忆队列的基线调查(2018-2023年),老年人完成整套神经心理评估及体格检查,自我报告全麻和手术史;使用logistic回归模型分析老年人全麻与MCI的关联性,此外,分别进行了麻醉史、麻醉次数与体智锻炼的分层及交互作用分析。结果本研究共纳入5 069名65岁及以上老年人,其中农村1 377人(27.1%),女性2 584名(51%),有全麻者1 427人 ...
张秋茹 +4 more
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近年来,轻度认知障碍(Mild cognitive impairment, MCI)作为阿尔茨海默病(Alzheimer’s disease,AD)的一个早期症状引发关注,对其进行早期干预具有积极意义。现有人群实验、动物实验及细胞实验多方面研究表明,多不饱和脂肪酸(PUFAs)中的ω-3多不饱和脂肪酸(ω-3 PUFAs)可以改善炎症反应,影响轻度认知障碍的发生发展。但ω-6多不饱和脂肪酸(ω-6 PUFAs)的相关代谢产物既包含抗炎物质,又有促炎物质,机制较为复杂,目前研究具有争议性 ...
刘佳欣,付朝旭,许妍姬 LIU Jiaxin, FU Chaoxu, XU Yanji
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Development,Reliability and Validity of a Concise,Prediction Model-based Nutritional Risk Assessment Scale for Nursing Home-dwelling Older People [PDF]
BackgroundThe Malnutrition Risk Assessment for Elderly Adults (WS/T 552-2017) , a malnutrition risk assessment scale issued by the National Health Commission has proven to have unsatisfied reliability and validity, with some inappropriate items in ...
ZHU Dan, XIE Hong
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