Results 41 to 50 of about 5,995 (167)
Association between Polymorphisms of ERCC1 and Response in Patients with Advanced Non-small Cell Lung Cancer Receiving Cisplatin-based Chemotherapy [PDF]
, 2010 Background and objective Results of studies on genetic polymorphisms of ERCC1 gene in DNA repair pathway which may affect response to platinum-based chemotherapy and survival in patients with non-small cell lung cancer are conflicting.
Hui ZHANG +6 more
core
Integrative Conservation, Volume 4, Issue 4, Page 555-568, December 2025.Sri Lanka's biodiversity is threatened by habitat loss, climate change, and ineffective traditional conservation methods. Integrating plant tissue culture and DNA barcoding offers scalable, precise tools for conserving rare and endemic species. This review emphasizes the potential of biotechnological approaches to enhance conservation accuracy and ...
Mylange Dona Kasundi Mekhala Gunasena +2 more
wiley +1 more source
Investigation of the role of innate immunity in pathogenesis of autoimmunity-associated pulmonary fibrosis [PDF]
, 2017 目的：肺纤维化（Pulmonaryfibrosis，PF）是一种慢性、致死性、弥散性的间质性肺病。在一些自身免疫病，比如系统性硬皮病（Systemicsclerosis，SSc）和原发性干燥综合征（primarySjögren’ssyndrome，pSS）里，PF也是一种常见的并发症并且是导致病人死亡的主要因素之一。值得注意的是，虽然这些自身免疫病患者都有自身免疫反应，但只有部分病人患有PF。这一现象表明除了自身免疫外，还有一些其他因素参与了PF的发生。但目前为止 ...
赵文洁
core
Integrative Conservation, Volume 4, Issue 4, Page 527-533, December 2025.The recommendations cover four key aspects namely the definition of the taxa require high priority in the biodiversity conservation management, enhanced flexibility and adaptivity of the implementation processes, enforced integration of research advancement to enable the sustainable usage of plant resources, and finally actions to propose transboundary
Shi‐Cheng Shao +4 more
wiley +1 more source
野生动物学报, 2011 应用RAPD技术分析了玳瑁的遗传多样性。用20个随机引物对中国南海海域玳瑁7个个体的基因组DNA进行了PCR扩增,共扩增出1 351条DNA片段,平均每个个体扩增出193条条带。在检测到的193条条带中,多态性条带为69条,多态性条带百分比为35.8%,条带大小在200 bp～3 000 bp之间,7个个体间遗传距离为0.082 9～0.1813,平均遗传距离为0.132 7±0.029 9,表明中国南海海域玳瑁的遗传多样性水平较低,应加强该区域玳瑁种质资源的保护。采用类平均聚类法（NJTREE ...
端金霞 +5 more
doaj
Isolation of microsatellite markers, construction of genetic linkage maps and QTL mapping of growth-related traits in small abalone, Haliotis diversicolor [PDF]
, 2011 本研究采用磁珠富集法，用14个探针构建了杂色鲍微卫星富集文库。从文库中随机选取768个阳性克隆进行测序，拼接得到729个重叠群，其中656个重叠群包含微卫星序列。利用微卫星两侧保守区域设计了583对微卫星引物，从中筛选出退火温度在50-64℃，PCR产物稳定扩增、条带清晰的微卫星标记308个。随机选取其中的11个微卫星标记用于标记质量评估，这11个微卫星标记的PIC值在0.7276到0.9163之间，具有高度多态性。 利用开发的308个微卫星标记，以养殖个体♀和野生个体♂杂交F1家系为作图群体 ...
战欣
core
Analysis of CSF1PO and D18S51 Loci Based on Ion Torrent PGMTM Platform [PDF]
, 2018 Objective To analyse and detect CSF1PO and D18S51 loci by next generation sequencing （NGS） technology for the study on their sequence polymorphism.
YANG Yi-zun, PING Yuan
core +1 more source
Construction of SNP-STR Multiplex Amplification System with Genetic Markers and Its Forensic Application [PDF]
, 2020 Objective To select and develop a SNP-STR multiplex amplification system with genetic markers compatible with current STR databases. To understand its genetic polymorphisms in Sichuan Han population and its application value in DNA mixture analysis ...
WANG Qiu-yue, YANG Yi-wen, CAO Yue-yan, et al
core +1 more source
Integrative Conservation, Volume 4, Issue 3, Page 405-415, September 2025.Assessing the genetic diversity of edible insects harvested from the wild is a pre‐requisite for designing conservation and management policies. The caterpillars of Gynanisa maja (Saturniidae) are harvested in large numbers in mopane woodlands in southern Africa, where they represent a seasonal source of income and nutrition to many rural communities ...
Zwannda Nethavhani +3 more
wiley +1 more source
, 2009 银鲫(Carassius auratus gibelio Bloch)由于其独特的遗传背景和繁殖方式而成为研究进化遗传学和选择育种的一个独特的模式生物。到目前为止,我们对新疆额尔齐斯河水系银鲫群体的多样性状况一直知之甚少。为了更好地了解额尔齐斯河水系银鲫群体的克隆多样性状况,本研究中,我们采集了来自新疆额尔齐斯河水系的4个鲫鱼群体。通过流式细胞术分析血细胞样品,结果证实这些鲫鱼均为三倍体银鲫。通过血清转铁蛋白电泳表型分析,我们从这些银鲫群体中鉴定出总共8个不同的克隆。在这些鉴定的克隆中,有4个克隆 ...
周莉, 李风波, 桂建芳
core