Results 31 to 40 of about 40,530 (211)

中晚期胃癌介入干预前后血清MG7-Ag、sIL-6R、VEGF的变化

open access: yesZhongguo shiyan zhenduanxue, 2011
目的观察血清MG7-Ags、IL-6R、VEGF在中晚期胃癌患者介入干预前后水平变化。方法选择中晚期胃癌患者50例,其中介入干预30例,静脉化疗20例,化疗药物选用5-氟脲嘧啶、亚叶酸钙及草酸铂,分别在干预前、干预后2周、干预后4周,清晨空腹留取静脉血5 ml,室温下静置半小时,再3 000 r/min离心10 min,留取血清进行检测,MG7-Ags、IL-6R、VEGF的测定采用ELISA法。结果介入干预组中MG7-Ags、IL-6R的水平呈下降趋势,在干预后4周 ...
张惠洁   +8 more
doaj  

Involvement of Abnormal MicroRNA Expression in the Mechanism of Drug Resistance with Acute Myeloid Leukemia [PDF]

open access: yes, 2016
目的:分析miRNA-98的表达异常在急性髓系白血病化疗耐药机制的作用,通过靶向过表达miRNA-98的表达水平探讨以miRNA-98为靶点增加化疗药物敏感性的可能性并分析其可能作用的机制。评价异常表达的血清miRNA-155是否可作为急性髓系白血病的预后标志。 方法:离体实验中,采用qRT-PCR方法检测K562和其耐药株K562/A02中miR-98、E2F1基因表达情况。通过瞬时转染miR-98mimic处理耐药细胞K562/A0248h后,通过qRT-PCR法检测miR-98表达情况;通过qRT-
黄英丹
core  

Perceived costs as drivers of wildlife management preferences in rural Tanzanian communities

open access: yesConservation Biology, EarlyView.
Abstract Effectively managing human–wildlife interactions is crucial for fostering coexistence on shared landscapes. Management options are most effective when aligned with the preferences of people directly affected by wildlife, yet little is known about how socioecological factors influence these preferences.
Christian Kiffner   +10 more
wiley   +1 more source

构建基于20基因的急性髓系白血病预后生存模型

open access: yesZhongguo shiyan zhenduanxue, 2021
目的利用Firehose数据库的数据,分析与急性髓系白血病(AML)发生、发展及预后相关的分子标志物,构建基于机器学习算法的AML 1年预后模型。方法从GDC(Genomic Data Commons)的外部链接Broad Firehose数据库中下载关于AML患者的临床及转录组数据,筛选出符合要求的生存期及mRNA测序数据的病历共163例。运用R语言DESeq程序包进行差异表达基因的筛选,并应用R语言的Rattle程序包构建基于20基因的AML 1年预后生存模型。结果 EBF4、MTUS2、NT5E ...
何文君   +3 more
doaj  

Implementing Omaha System evaluation on stroke clients’ community rehabilitation [PDF]

open access: yes, 2017
2011-2012 > Academic research: refereed > Publication in refereed journalVersion of ...
万巧琴   +4 more
core  

Artificial Intelligence for Language Learning: A Systematic Review of its Design, Theoretical Foundations, Implementation, and Impact

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Although the use of AI technologies (e.g., chatbots and automated writing evaluations (AWE)) has gained considerable attention in language learning fields in recent years, how AI technologies have been designed and implemented in language learning education, as well as their effectiveness, is understudied.
Shen Qiao   +2 more
wiley   +1 more source

Clinicopathological Research and Expression of PTEN/PI3K/Akt Signaling Pathway in Non-small Cell Lung Cancer [PDF]

open access: yes, 2009
Background and objective It has been known that abnormality of PTEN/PI3K/Akt signal pathway played an important role in initiation of some malignant tumors.
Can XU   +3 more
core  

Language Mindset and Discipline Mindset Both Matter: Exploring the Effect of Growth Mindset on Motivation and Willingness to Communicate in EMI Higher Education

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT In English medium instruction (EMI), students face cognitive and emotional demands in second language (L2) communication, which may hamper their motivation and willingness to communicate (WTC). Adopting a mixed‐methods design, this study explores how growth mindsets affected student motivation (e.g., ideal L2 self and ideal disciplinary self ...
Pengzhan Yang   +2 more
wiley   +1 more source

hs-cTnT和NT-proBNP在急性心肌梗死患者预后中的价值研究

open access: yesZhongguo shiyan zhenduanxue, 2016
目的探索hs-cTnT和NT-proBNP在急性心肌梗死患者预后中的临床价值。方法纳入2013年1月至2014年12月共347例AMI患者为研究对象,按预后分为预后良好组(272例)和预后不良组(75例)。比较两组患者hs-cTnT和NT-proBNP水平,分析预后良好组和预后不良组入院及出院hs-cTnT和NT-proBNP水平差异。结果在预后不良组中出院hs-cTnT水平为3127.0(1638.0-6054.0)ng/L,高于入院hs-cTnT的1390.0(291.7-4189.0)ng/L ...
周莉莎   +5 more
doaj  

The Clinical Signifcance of Expression of ERCC1 and PKCalpha in Non-small Cell Lung Cancer [PDF]

open access: yes, 2010
Background and objective Excision repair cross-complementing 1 (Excision-Repair Cross-Complementing 1, ERCC1), an important member of the DNA repair gene family, plays a key role in nucleotide excision repair and apoptosis of tumor cells.
Guangming LI   +6 more
core   +1 more source

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