Results 51 to 60 of about 40,530 (211)

Prognostic awareness, will to live and health care expectation in patients with terminal cancer [PDF]

open access: yes, 2017
2005-2006 > Academic research: refereed > Publication in refereed journalVersion of ...
Leung, WK, Pang, LZ, Pang, MC, Shi, YX
core  

Assessing the integration of social marketing principles in ivory demand management interventions in China and Southeast Asia

open access: yesConservation Biology, Volume 40, Issue 2, April 2026.
Abstract Consumer demand for ivory perpetuates the unsustainable and illegal killing of African elephants and other wildlife species. Interventions that aim to change consumer behavior are increasingly recognized as a crucial element of demand management. However, poor design and implementation have limited their effectiveness.
Molly R. C. Brown   +2 more
wiley   +1 more source

构建基于铁死亡相关长链非编码RNA的胆管癌预后模型

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 在胆管癌(CCA)中用铁死亡相关长链非编码RNA(lncRNA)建立有较好的预测能力的预后模型。方法 从TCGA数据集下载CCA的转录组RNA-seq数据和相应的临床数据。采用Pearson相关法筛选与铁死亡相关的差异表达的lncRNAs。单因素Cox回归分析用来筛选与预后相关的lncRNAs。通过多因素回归分析构建预后模型,采用受试者工作特征曲线(ROC)下面积和Kaplan-Meier曲线对模型进行评价。结果 筛选出3个铁死亡相关的差异表达lncRNAs:LINC01714 ...
张琳, 石张镇, 白元松
doaj  

The Analysis of Erlotinib on Brain Metastases in Patients with Non-small-cell Lung Cancer [PDF]

open access: yes, 2009
Background and objective Brain metastases are common in non-small-cell lung cancer (NSCLC) and the prognosis is poor. Erlotinib is a specific inhibitor of the epidermal growth factor receptor-associated tyrosine kinase (EGFRTKI), which has been gradually
Baohui HAN, Hao BAI
core  

Research of diagnostic biomarkers in Breast cancer and Gastric cancer [PDF]

open access: yes, 2013
自生物标志物(biomarker)这一概念提出以来,肿瘤生物标志物(tumorbiomarker,TBM)在基础医学领域的研究已成为热点。本文基于大量的临床病理样本,利用免疫组织化学、甲基化芯片分析、实时荧光定量PCR等技术,研究乳腺癌、胃癌预后诊断的生物标志物,为疾病的治疗提供新的思路和靶点。 我们利用免疫组织化学,调查了酪氨酸磷酸酶Shp2和它的伴侣蛋白Gab2在141例乳腺浸润性导管癌中的表达,并分析了他们与临床病理学特征的相关性,发现Gab2蛋白表达与病人的年龄存在显著相关性 ...
陈宝珍
core  

Long-term Survival of Personalized Surgical Treatment of Locally Advanced Non-small Cell Lung Cancer Based on Molecular Staging [PDF]

open access: yes, 2011
Background and objective Approximately 35%-40% of patients with newly diagnosed non-small cell Lung cancer have locally advanced disease. The average survival time of these patients only have 6-8 months with chemotherapy.
Bin LIU   +16 more
core  

血清指标对陈旧性胸腰段骨折患者预后影响及营养干预的实验研究

open access: yesZhongguo shiyan zhenduanxue
目的 分析血清学、营养指标与陈旧性胸腰段骨折患者预后的相关性,并评价营养干预对患者预后的实验研究。方法 选择2019年1月至2023年1月在河北省沧州中西医结合医院行人工椎体置换术治疗的60例陈旧性胸腰段骨折患者作为研究对象,依据患者预后分为预后不良组及预后良好组,测定两组患者前白蛋白(PA)、血红蛋白(HB)、转铁蛋白(TF)、白蛋白(ALB)、总蛋白(TP)、肌酐(Cr)、淋巴细胞(LYM)及血钙水平,并计算患者预后营养指数(PNI ...
苏冬冬, 王芳芳
doaj  

Studies of cerebral venous circulation and coagulation function in patients with aneurysmal subarachnoid hemorrhage [PDF]

open access: yes, 2016
目的:1.利用全脑血管造影技术(DSA)和磁敏感加权成像(SWI)观察动脉瘤性蛛网膜下腔出血(aSAH)患者脑静脉循环的变化,并探讨其对患者病情的判断价值。 2.利用血栓弹力图(TEG)研究aSAH患者凝血功能的变化,旨为评估患者凝血及纤溶系统的改变提供新的思路。 方法:1.收集南京军区福州总医院57例aSAH患者、48例未破裂动脉瘤患者及45例非动脉瘤患者(正常对照组),利用DSA观察并比较三组患者脑微循环时间(mCCT)及脑静脉循环时间(vCCT)及脑微血管及皮质静脉的显影特征。 2 ...
李兵兵
core  

心率变异性分析与急性缺血性卒中不良预后的关系

open access: yesZhongguo shiyan zhenduanxue
目的探讨心率变异性(HRV)与急性缺血性卒中(AIS)患者不良预后的关系,为早期干预不良结局提供科学依据。方法选取2024年8月至2025年4月吉林省人民医院神经内科收治的AIS患者作为研究对象,所有患者在入院后7天内进行HRV评估、一般资料收集。统计出院后90天的预后情况并根据改良 Rankin评分量表(mRS)评分、病情复发情况将患者分为预后良好组与预后不良组,比较两组患者HRV指标。多因素Logistic 回归分析与 AIS 患者不良预后危险因素 ...
徐帆, 李贯绯, 李淞
doaj  

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