Results 1 to 10 of about 9,041 (170)
[Research Progress on the Mechanism and Diagnostic Markers of Bone Metastasis in Small Cell Lung Cancer]. [PDF]
Zhongguo Fei Ai Za Zhi小细胞肺癌（small cell lung cancer, SCLC）是一种恶性程度高、转变迅速、侵袭转移快的肺癌亚型，极易出现早期转移，预后较差。SCLC骨转移共经历癌细胞在原发部位增殖并突破局部组织、进入血液循环形成循环肿瘤细胞（circulating tumor cells, CTCs）并通过血液循环到达骨组织、到达骨组织后在骨微环境的支持下生根发芽形成新的肿瘤灶等三大阶段，而传统的影像学、病理学检查具有敏感性低、价格昂贵、实施难度大等缺点 ...
Xiang X, Nan Y.
europepmc +2 more sources
[Mechanism of Bone-metastatic LUAD Cells Promoting Angiogenesis Through HGF/YAP Signaling Pathway]. [PDF]
Zhongguo Fei Ai Za Zhi背景与目的 肿瘤骨转移早期与骨微环境血管生态位改变密切相关，异常的血管生成加速肿瘤转移进展，但骨微环境中肺腺癌细胞对血管生态位的作用及其机制仍不清楚。本研究通过探讨骨微环境驯化的肺腺癌细胞株对内皮细胞及血管生成的影响及机制，为骨微环境肿瘤细胞对血管生态位的影响提供参考。 方法 用骨微环境驯化的肺腺癌细胞A549-GFP-LUC-BM3（BM3）培养上清（BM3-CM）和A549-GFP-LUC（A549）培养上清（A549-CM）分别作用于人脐静脉内皮细胞（human umbilical vein ...
Deng Y, Qiu R, Liu X, Su Y, Xue Y, Du Y.
europepmc +2 more sources
[Establishment of Dual Fluorescent Labeled Human High Bone Metastasis Lung Adenocarcinoma Cell Line and Transcriptomic Characterization Analysis]. [PDF]
Zhongguo Fei Ai Za Zhi背景与目的 骨是肺腺癌常见的转移部位，但肺腺癌骨转移的机制尚不明确。目前肺腺癌骨转移机制研究缺乏易于示踪且稳定高骨转移的肺腺癌细胞模型，因此，本研究旨在建立绿色荧光蛋白（green fluorescent protein, GFP）和萤火虫荧光素酶（firefly luciferase, LUC）双标记的人高骨转移肺腺癌细胞株，为肺腺癌骨转移的研究提供新的实验工具。 方法 人肺腺癌细胞系A549-GFP-LUC经左心室注射至裸鼠体内构建骨转移模型，经连续3次体内驯化，获取人高骨转移肺腺癌细胞株A549 ...
Lu Y, Qiu R, Deng Y, Liu X, Du Y.
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Zhongshan Daxue xuebao. Yixue kexue ban, 1987 本文报告自1964～1981年经外科治疗的女性单侧乳腺癌1656例,随访1—18年(中位11年),有128例发生骨转移,骨转移率为7.7％。骨转移的主要部位为脊柱(46.6％),肩胛带(15.1％),骨盆带(10.9％),显示乳腺癌的骨转移与肋间——脊椎静脉系统密切相关。本组术后发生骨转移的中位时间为22个月,发现骨转移后的中位生存时间为7个月。影响乳腺癌术后骨转移的主要因素为乳腺癌的病理组织学类型及区域淋巴结转移情况。作者认为预访和减少乳腺癌骨转移率的切实可行的措施是早期发现、早期诊断、早期治疗 ...
詹友庆
doaj +2 more sources
Equine Veterinary Journal, Volume 55, Issue 2, Page 261-269, March 2023., 2023 Summary Background In clinical practice, early diagnosis of Equine Odontoclastic Tooth Resorption and Hypercementosis (EOTRH) and other resorptive incisor diseases is difficult to achieve. The radiographic appearance of subtle pathological changes has not been described in detail and might be confused with age‐related changes.
Louisa Albers +4 more
wiley +1 more source
A meta-analysis of the efficacy of 99Tc-MDP alone and in combination with 89SrCl2 in the treatment of bone metastases [PDF]
, 2023 Background and purpose: Bone metastatic tumor is a common disease of tumor bone metastasis, and the prognosis of patients is poor, with a variety of serious complications, including bone pain, fracture, spinal cord compression and other skeletal related ...
CHEN Man, ZENG Feiyan, LI Qingqing, LI Hongdan, LIN Yansong, FENG Ping
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Research progress in the relationship between plasma FIB and prostate cancer [PDF]
, 2023 The incidence of prostate cancer （PCa） has been increased year by year， mainly occurring in elderly men. Currently， prostate-specific antigen （PSA） is still used as a marker for diagnosing PCa in clinical practice.
Zhang Peng, Han Conghui, Liu Dachuang
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Role of 18F-MD-PSMA PET/CT in initial stage of intermediate and high risk prostate cancer [PDF]
, 2023 Objective·To evaluate the role of 18F-MD-PSMA PET/CT in the initial stage of patients with moderate and high risk prostate cancer (PCa).Methods·A total of 67 patients with moderate and high risk PCa who were treated in Xinhua Hospital, Shanghai Jiao Tong
CAI Lisheng +7 more
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Guidelines for breast cancer diagnosis and treatment by China Anti-cancer Association (2024 edition) [PDF]
, 2023 According to the latest data released by the International Agency for Research on Cancer of the World Health Organization (WHO), breast cancer has become the malignant tumor with the highest incidence rate around the world, seriously endangering the ...
The Society of Breast Cancer China Anti-Cancer Association, Breast Oncology Group of the Oncology Branch of the Chinese Medical Association
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实用医学研究, 2019 肝细胞性肝癌是一种常见的恶性肿瘤，死亡率很高。肝癌的主要症状是进行性骨痛和功能障碍，这给癌症患者带来了极大的痛苦，降低了生活质量，会导致严重的骨骼损伤。疼痛缓解剂和放射治疗是临床常用的疼痛治疗方法，已取得显著效果。护理好肝癌并全身骨转移患者是每一个护士应尽的职责，但护理过程是一个非常复杂的过程。能否实行有效的护理是对护士的一种考验。针对本科室近期收入的一例晚期肝癌全身骨转移患者实施护理,针对肝癌骨转移患者病理、心理状况给予心理护理、基础护理、止痛、营养支持、骨转移疼痛治疗等针对性护理 ...
倩倩 王
semanticscholar +1 more source