Results 11 to 20 of about 1,655,239 (149)

Fasting and refeeding triggers specific changes in bile acid profiles and gut microbiota 禁食和再进食触发胆汁酸谱和肠道微生物群的特异性变化

open access: yesJournal of Diabetes, Volume 15, Issue 2, Page 165-180, February 2023., 2023
Highlights For the first time, our study contributed a systematic evaluation of bile acid (BA) profiles in plasma, feces and liver tissue and gut microbiota changes triggered by fasting‐refeeding cycle in mice. Our work clearly demonstrated that overnight fasting leads to significant, but reversible changes in BA profiles and gut microbiota composition.
Yi Zhang   +16 more
wiley   +1 more source

Chemical and microbiological stability of diluted ceftazidime in three different solutions under three storage temperatures over a 28 day period

open access: yesVeterinary Dermatology, Volume 32, Issue 5, Page 456-e124, October 2021., 2021
Background – Ceftazidime (CAZ) solutions are being used based on anecdotal reports for otitis externa complicated by multidrug‐resistant Pseudomonas aeruginosa (MDR PA). The chemical and microbiological stability of these proposed compounded solutions have not been evaluated, and likely are affected by the diluent and storage duration or temperature ...
Sarah E. Hoff   +4 more
wiley   +1 more source

液液萃取高效液相色谱法分析水源水中酚类和苦味酸

open access: yesGongye shui chuli, 2018
关键词: 水质分析, 酚类化合物, 苦味酸, 液液萃取 ...
马飞攀   +4 more
doaj  

脑胶质瘤病人遗传易感基因单核苷酸多态性的研究

open access: yesZhongguo shiyan zhenduanxue, 2006
目的筛查与脑胶质瘤发病相关基因的单核苷酸多态性,进一步寻找胶质瘤易感基因。方法收集入院脑胶质瘤病人的血液。应用PCR扩增的方法对肿瘤相关的基因的特定片段进行扩增。利用变性高效液相色谱技术进行筛查。双向DNA直接测序,在GENBANK进行对比找到突变的碱基,并进行分析。结果变性高效液相色谱筛查后表明,在HLA-DMA基因中检测到了已知杂和性突变,并发现新的突变,HLA-DMA4EC杂合性缺失突变。结论变性高效液相色谱技术在筛查基因的SNPs方面显示了其快速、高通量和准确的特点。HLA ...
徐保锋   +4 more
doaj  

植物油中邻苯二甲酸酯类塑化剂检测技术研究进展 Research progress on the detection technology of phthalate esters plasticizers in vegetable oils

open access: yesZhongguo youzhi
邻苯二甲酸酯(PAEs)类塑化剂是一种环境污染物,具有生殖毒性,易致癌、致畸,植物油易受到PAEs污染。旨在为植物油中PAEs类塑化剂检测方法的开发提供参考,对植物油中PAEs类塑化剂检测技术的前处理方法和定量检测技术进行了综述,比较了各方法的优缺点,并对其发展趋势进行了展望。PAEs类塑化剂检测的前处理方法包括液-液萃取法、固相萃取法、凝胶渗透色谱法和QuEChERS法等;定量检测技术包括高效液相色谱法、气相色谱法、液相色谱-质谱联用法、气相色谱-质谱联用法等。未来联合前处理技术、在线净化、微萃取 ...
贺诗意1,2,张蕊1,周明慧1,王松雪1,朱琳1,付湘晋2 HE Shiyi1,2,ZHANG Rui1,ZHOU Minghui1,WANG Songxue1, ZHU Lin1,FU Xiangjin2
doaj   +1 more source

Effects of Different Monochromatic Light on Growth, Pigments and Citrinin Biosynthesis of Monascus purpureus(不同单色光对紫色红曲霉生长、色素和桔霉素合成的影响) [PDF]

open access: yesShipin kexue jishu xuebao, 2019
Effects of different monochromatic lights (red, yellow, green and blue) on culture morphology and six well known pigments production of Monascus purpureus M9 were investigated in this study.
LIU Hong(刘宏)   +4 more
doaj   +1 more source

微萃取瓶富集-液相色谱法测定水中痕量壬基酚

open access: yesGongye shui chuli, 2010
应用自制微萃取瓶,采用异辛烷作萃取剂,液-液微萃取方法富集水中壬基酚,反相高效液相色谱法测定。考察了不同萃取剂、盐析效应和pH对萃取效果的影响。壬基酚在水中的加标回收率为91.77%,方法检出限为0.525μg/L,相对标准偏差为1.82%。该萃取方法可有效富集水中痕量壬基酚。
周建科, 彭静, 龙堃
doaj  

水环境中的二甲双胍及其去除工艺研究进展

open access: yesGongye shui chuli, 2022
二甲双胍(MET)是治疗Ⅱ型糖尿病的常用药物,在世界范围内被广泛使用。自1980年以来,国内MET使用量逐年增加。MET无法被人体代谢,经患者口服之后,约70%的MET会以体液形式排出体外,随生活污水进入污水处理厂。MET结构稳定,常规水处理工艺对其去除效果有限,因而在多种环境介质中均检测出含有MET。基于国内外相关文献,总结了MET在污(废)水、地表水及饮用水等环境介质中的浓度水平。在此基础上归纳了MET在环境水样检测中常用的分析方法,包括固相萃取(SPE)样品前处理方法、以及高效液相色谱串联质谱 ...
宋洪星   +3 more
doaj  

工业制备高效液相色谱法制备淫羊藿中的黄酮系列对照品

open access: yes, 2011
工业制备高效液相色谱法制备淫羊藿中的黄酮系列对照
王莉, 肖红斌, 彭杰, 高明哲
core   +1 more source

两种血清苯丙氨酸高效液相色谱测定法的比较

open access: yesZhongguo shiyan zhenduanxue, 2005
目的对两种血清苯丙氨酸高效液相色谱测定法进行比较。方法对高效液相色谱-紫外检测法(HPLC-UV)和高效液相色谱-荧光检测法(HPLC-FLD),从线性范围,检测限,精密度等参数上进行比较,用两种方法分别测定了正常儿童和一组PKU患儿血清phe值,对结果进行统计分析。结果HPLC-UV法和HPLC-FLD法的线性范围分别为61512μmol/L和121220μmol/L,最低检测限分别为0.75μmol/L和3μmol/L,平均回收率分别为98.6%和102.5 ...
唐爱国, 洪敏, 莫喜明, 陈若虹
doaj  

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