Results 121 to 130 of about 16,984,232 (292)
Light baryonium states with exotic quantum numbers
European Physical Journal C: Particles and FieldsThe existence of baryonium-bound or resonant states composed of a baryon and an antibaryon has long been postulated as a natural extension of conventional hadron spectroscopy.
Bing-Dong Wan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
European Physical Journal C: Particles and FieldsStimulated by the recent experimental results on the fully-charm tetraquark states, we systematically calculate the mass spectra of the fully-charm tetraquark states in $$8_{[c\bar{c}]}\otimes 8_{[c\bar{c}]}$$ 8 [ c c ¯ ] ⊗ 8 [ c c ¯ ] color ...
Chun-Meng Tang +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
European Physical Journal C: Particles and FieldsIn this work, we calculate the magnetic moments of the $$P^{N^{0}}_{\psi }$$ P ψ N 0 states and $$P^{\Delta ^{0}}_{\psi }$$ P ψ Δ 0 states with valence quark content $${\bar{c}}cudd $$ c ¯ c u d d in molecular model, diquark–diquark–antiquark model and ...
Fei Guo, Hao-Song Li
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
New insights into the doubly charmed exotic mesons
European Physical Journal C: Particles and FieldsUsing effective Lagrangians constrained by the heavy quark spin symmetry and chiral symmetry, for the light quarks, we analyze the $$D^0 D^0\pi ^+,$$ D 0 D 0 π + , $$\bar{D}^0D^0\pi ^0$$ D ¯ 0 D 0 π 0 and $$D^0\bar{D}^{*0}$$ D 0 D ¯ ∗ 0 invariant mass ...
Di Guo +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source