Results 101 to 110 of about 10,486,500 (294)
Finding Worlds That Look Like Stars [PDF]
, 2001 This hands-on activity introduces students to searching for asteroids.
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Quantifying Changes in the Land Over Time: A Landsat Classroom Activity [PDF]
, 2006 Students in grades 7-10 analyze land cover change in order to help them grasp the extent, significance, and consequences of land cover change; and to introduce them to the perspective of space-based observations.
NASA GSFC
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
, 2003 MERLOT is a community of educators in higher education who collaborate to develop and disseminate high quality online resources for faculty to incorporate into their courses.
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
A Study of Junior High Students' Perceptions of the Water Cycle [PDF]
, 2007 Provides pedagogical insight concerning learners' pre-conceptions and misconceptions about the water cycle The resource being annotated is: http://www.dlese.org/dds/catalog_DLESE-000-000-003-365 ...
Lamont-Doherty Earth Observatory, Columbia University
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
, 2010 This exercise allows students to compare and contrast the nucleus of two comets and listen to audio files of NASA scientists and middle-school students conducting the activity.
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