Results 111 to 120 of about 10,486,500 (294)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Kartografija i Geoinformacije, 2006 The procedure to determine the coastline length and the area of the island of Rab from the maps at the scales 1:25 000, 1:50 000, 1:100 000, 1:200 000, 1:300 000, 1:500 000, 1:1 000 000 and 1:2 000 000 is described. The map sheets at the scales 1:25 000,
Nada Vučetić +2 more
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Sand or Rock: Finding Out From 1000km [PDF]
, 2001 This hands-on activity explores the nature of thermal inertia.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Exploring the Edge of Our Solar System: IBEX Mission (Poster) [PDF]
, 2008 This poster outlines the major mission highlights of the Interstellar Boundary Explorer (IBEX) mission, a Small Explorer Earth-orbiting spacecraft that is designed to map the distant boundary between the solar wind from our Sun and the interstellar ...
Michelle Nichols
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
, 2005 This model airplane is designed to resemble the Swift bird, which conveys information about NASA’s Swift gamma-ray burst Explorer mission.
Lynn Cominsky
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
, 1997 This resource is a 43 page pdf document on the principals of optical mineralogy. Topics include light, the polarizing light microscope, the refractive index, optical classes and indicatrix theory, the relationship of optical properties to crystal ...
Mickey Gunter
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