Results 141 to 150 of about 11,521 (228)

Molecular Docking and Target‐Specific Binding Profiles of Benzosuberane‐Based Compounds

open access: yesChemMedChem, EarlyView.
Benzosuberane represents a promising scaffold in medicinal chemistry. Several benzosuberane‐based derivatives are described in this review as anticancer agents, including antivascular agents, DNA‐intercalators, receptor modulators and kinase inhibitors.
Michail A. Saragatsis   +3 more
wiley   +1 more source

Monitoring Receptor Clustering by Aggregation‐Induced Emission

open access: yesChemPlusChem, EarlyView.
Receptor clustering induced by molecular recognition: AIE‐functionalized bisphosphonate receptors are embedded in a lipid bilayer. Upon addition of a cationic messenger, they undergo dimerization and send out a fluorescence signal. This study introduces a simple signal transduction system that mimics the receptor tyrosine kinase mechanism by employing ...
Robert Bekus   +4 more
wiley   +1 more source

Synthesis of Functional 1,2,3-Triazoles and Its Applications in Transition Metal Catalysis [PDF]

open access: yes, 2012
Several new methodologies for synthesizing functional 1,2,3-triazoles which include arylation, vinylation, propargylation and allenation, have been successfully developed.
Yan, Wuming
core   +1 more source

Green and Sustainable Chemistry Approaches on Azide‐Based Click Reactions in Polymer Science

open access: yesMacromolecular Rapid Communications, EarlyView.
Click Chemistry, particularly the azide‐alkyne cycloaddition (AAC) reaction, has revolutionized polymer chemistry, enabling precise and efficient synthesis of advanced functional materials. With its high regioselectivity, mild reaction conditions, and versatility, AAC reactions align closely with the principles of Green and Sustainable Chemistry.
Hatice Mutlu   +3 more
wiley   +1 more source

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg   +3 more
wiley   +1 more source

One‐Pot Four‐Component Synthesis of Novel Amino‐Tetrahydro‐Chromene Derivatives Anchored with Dual Triazole Moieties

open access: yesChemistryOpen, EarlyView.
A series of tetrahydrochromene derivatives bearing triazole rings is synthesized via a one‐pot reaction. The process is optimized by ultrasonication of a basic aqueous tert‐butanol mixture. Subsequently, the optimized steps are successfully integrated into a four‐component, one‐pot protocol. The whole process was completed in less than 2 h.
Saeede Azhari   +2 more
wiley   +1 more source

A tribute to Professor Dr Kai A. I. Zhang: pioneering advances in metal‐free polymeric photocatalysis

open access: yesPolymer International, EarlyView.
Polymeric photocatalysts have emerged as metal‐free materials with tunable structures. This review highlights the contributions of Professor Dr Kai A. I. Zhang in advancing polymer‐based photocatalysts. Abstract Polymeric photocatalysts have emerged as promising alternatives to traditional metal‐based catalysts due to their tunable properties, low cost
Bolormaa Bayarkhuu   +2 more
wiley   +1 more source

Reaction Mechanisms of Transition-Metal-Catalyzed Azide-Alkyne Cycloaddition “Click” Reactions: A DFT Investigation

open access: yes, 2015
International audienceDFT calculations at the PBE0/LANL2DZ level have been performed on model compounds to investigate the reaction mechanism of two recently reported metal-catalyzed alkyne azide cycloaddition (MAAC).
Astruc, Didier   +5 more
core   +2 more sources

Solvothermal Synthesis of Porous Aminated Poly(1,2,4‐Triazolium) Networks and Their Use in CO2 Capture and Conversion

open access: yesJournal of Polymer Science, EarlyView.
Porous aminated poly(1,2,4‐triazolium) networks carrying varied counter anions were synthesized via solvothermal polymerization of a 1,2,4‐triazolium monomer with divinylbenzene as crosslinker. Their behaviors in CO2 capture and conversion were studied in detail.
Elnaz Tahavori   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy