Results 141 to 150 of about 37,751 (208)

1,2,4-Triazines Are Versatile Bioorthogonal Reagents

Journal of the American Chemical Society, 2015
A new class of bioorthogonal reagents, 1,2,4-triazines, is described. These scaffolds are stable in biological media and capable of robust reactivity with trans-cyclooctene (TCO). The enhanced stability of the triazine scaffold enabled its direct use in recombinant protein production.
Yong Liang, Fang Liu, Kendall Houk
exaly   +3 more sources

1,2,4‐Triazines

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
C. W. Lindsley, M. E. Layton
openaire   +1 more source

1,2,4‐Triazine N‐Oxides

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
D.N Kozhevnikov, V.L Rusinov, O.N Chupakhin   +2 more
openaire   +1 more source

Antimalarials. 3. 1,2,4-Triazines

Journal of Medicinal Chemistry, 1976
The syntheses of a number of substituted 1,2,4-triazines as potential antimalarials are described. The structural requirements for antimalarial activity are discussed with reference to the substituents of a phenyl group in the 6 position and amino groups at the 3 and 5 positions.
L C, March, G S, Bajwa, J, Lee, K, Wasti, M M, Joullíe   +4 more
openaire   +2 more sources

3-Amino-1,2,4-triazine

Acta Crystallographica Section C Crystal Structure Communications, 2002
In the crystal structure of 3-amino-1,2,4-triazine, C(3)H(4)N(4), the molecules form hydrogen-bonded chains that are almost parallel to the b axis (3.2 degrees), and which are inclined to the a and c axes by approximately 21 and approximately 69 degrees, respectively.
Genivaldo Julio, Perpétuo, Jan, Janczak
openaire   +2 more sources

Synthesis and Anti-Inflammatory Evaluation of 3-Methylthio-1,2,4-Triazines, 3-Alkoxy-1,2,4-Triazines, and 3-Aryloxy-1,2,4-Triazines

Journal of Pharmaceutical Sciences, 1980
To develop nonacidic, nonsteroidal anti-inflammatory agents without GI complications, a series of asymmetric triazines was synthesized and evaluated for anti-inflammatory efficacy in the carrageenan-induced pedal edema assay. Toxicity was estimated by determination of approximate LD50 values in mice.
W P, Heilman, R D, Heilman, J A, Scozzie, R J, Wayner, J M, Gullo, Z S, Ariyan   +5 more
openaire   +2 more sources

ChemInform Abstract: 1,2,4‐TRIAZINES PART 10, DIMERIZATIONS OF 1,2,4‐TRIAZINES

Chemischer Informationsdienst, 1973
AbstractAus den 1,2,4‐Triazinen (I) mit freier 5‐Stellung erhält man in der angegebenen Weise bei der Behandlung mit Methylat oder mit Kaliumcyanid über anionische Zwischenstufen Dimere wie (II).
D. K. KRASS, T.‐K. CHEN, W. W. PAUDLER
openaire   +1 more source

1,2,4-Triazine

2001
[290-38-0] C3H3N3 (MW 81.09) InChI = 1S/C3H3N3/c1-2-5-6-3-4-1/h1-3H InChIKey = FYADHXFMURLYQI-UHFFFAOYSA-N (electron-deficient heteroaromatic azadiene capable of participation in inverse electron demand Diels–Alder reactions with electron-rich dienophiles1) Alternate Names: as-triazine; α-triazine; isotriazine ...
Dale L. Boger, Minsheng Zhang
openaire   +1 more source

Chemistry of 1,2,4‐triazines, XV. First metalation of 1,2,4‐triazine derivatives

Liebigs Annalen der Chemie, 1993
Abstract5‐Methoxy‐1,2,4‐triazines 2 were lithiated with lithium 2,2,6,6‐tetramethylpiperidide and the formed 6‐lithio‐5‐methoxy‐1,2,4‐triazines 4 trapped with aldehydes or iodine.
Nelly Plé, Alain Turck, Guy Quéguiner, Bernd Glassl, Hans Neunhoeffer   +4 more
openaire   +1 more source