Results 21 to 30 of about 84,221 (197)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015 Aim. We have continued the study of 1,2,4-triazole derivatives, which contain 2-, 3- , 4-methoxyphenyl or 3,4,5- methoxyphenyl substituents in 5th position of the triazole nucleus.
Yu. G. Samelyuk , A. G. Kaplaushenko
doaj +1 more source
Data in Brief, 2021 Data from eight 1,2,4-thiadiazole-1,2,4-triazole derivatives were used to observe the anti-epidermal growth factor receptor kinase activities of 1,2,4-thiadiazole-1,2,4-triazole analogues thereby reducing human lung cancer.
Abel Kolawole Oyebamiji +6 more
doaj +1 more source
Molecules, 2021 The present paper is devoted to the search for drug-like molecules with anticancer properties using the thiazolo[3,2-b][1,2,4]triazole-6-one scaffold.
S. Holota +5 more
semanticscholar +1 more source
Physical-chemical properties of 5-(3-fluorophenyl)-4-amino-1,2,4-triazole-3-thiol s-derivatives
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017 Introduction. Currently an attempt to combine 1,2,4-triazole heterocycle with various pharmacologically active fragments of other organic molecules is popular among the scientists.
O. A. Bihdan, V. V. Parchenko
doaj +1 more source
Журнал органічної та фармацевтичної хімії, 2021 Aim. To synthesize 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and study its reactivity in the reaction with aldehydes. Results and discussion.
D. М. Zozulynets +2 more
doaj +1 more source
Tandem transformations of 1,2,4-triazol-5-ylidenes into 5-amidino-1,2,4-triazoles [PDF]
Arkivoc, 2007 The first tandem autotransformations of heteroaromatic carbenes have been found. These reactions involve cleavage of the 1-tert-butyl-3,4-diaryl-1,2,4-triazol-5-ylidenes 1a-d to form benzonitriles and the respective carbodiimides, followed by further reactions of the latter with carbenes 1a-d to afford the 3,4-diaryl-5-(1-tert-butyl-3-arylamidin-2-yl ...
Korotkikh, Nikolai I. +6 more
openaire +4 more sources
Synthesis of New Bis-1,2,4-Triazole Derivatives [PDF]
Molecules, 2006 A series of new 1,2/1,3-bis[o-(N-methylidenamino-3-aryl-5-phenyl-4H-1,2,4-triazole-4-yl)phenoxy]ethane/propane derivatives 4 were prepared in good yields bytreatment of 4-amino-3-aryl-5-phenyl-4H-1,2,4-triazoles 2 with certain bis-aldehydes 1.Compounds 4 were reduced with NaBH4 to afford the corresponding 1,2/1,3-bis[o-(N-methylamino-3-aryl-5-phenyl-4H-
Bekircan, Olcay, Bektas, Hakan
openaire +5 more sources
Synthesis and alkylation of 5-aryl-1,2-dihydro-3H-1,2,4-triazole-3-thiones
Журнал органічної та фармацевтичної хімії, 2021 5-R-1,2,4-triazole-3-thiones and their derivatives are easy to obtain; they have low toxicity and a broad spectrum of the biological activity. It makes this class of heterocyclic compounds promising for creating potential drugs. Aim.
Dmytro V. Dovbnya +2 more
doaj +1 more source
Coordination Polymers based on 1,2,4-Triazole
, 2021 This publication is part of the proceedings of the Biot-Bažant Conference on Engineering Mechanics and Physics of Porous Materials, which took place virtually on June 1-3, 2021. It contains a one-page abstract and the video of the talk that was given at the conference.
biot-bazant, figshare admin +2 more
openaire +1 more source
5-Amino-3-(4H-1,2,4-triazol-4-yl)-1H-1,2,4-triazole [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 The asymmetric unit of the title compound, C(4)H(5)N(7), comprises two independent but virtually superimposable mol-ecules. Each mol-ecule is planar with the dihedral angles between the five-membered rings being 2.8 (3) and 2.1 (3)°. The crystal structure is formed by an extensive network of relatively strong N-H⋯N hydrogen-bond inter-actions ...
Bing Liu +4 more
openaire +3 more sources