Журнал органічної та фармацевтичної хімії, 2021 Aim. To synthesize 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and study its reactivity in the reaction with aldehydes. Results and discussion.
D. М. Zozulynets +2 more
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Computationally motivated synthesis and enzyme kinetic evaluation of N-(β-d-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors [PDF]
, 2015 Following our recent study of N-(β-D-glucopyranosyl)-oxadiazole-carboxamides (Polyák et al., Biorg. Med. Chem. 2013, 21, 5738) revealed as moderate inhibitors of glycogen phosphorylase (GP), in silico docking calculations using Glide have been performed ...
Alex +57 more
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Synthesis and alkylation of 5-aryl-1,2-dihydro-3H-1,2,4-triazole-3-thiones
Журнал органічної та фармацевтичної хімії, 2021 5-R-1,2,4-triazole-3-thiones and their derivatives are easy to obtain; they have low toxicity and a broad spectrum of the biological activity. It makes this class of heterocyclic compounds promising for creating potential drugs. Aim.
Dmytro V. Dovbnya +2 more
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Thermal behavior of polytriazole films: a thermal analysis study [PDF]
, 1989 The thermal behavior of poly(1,3-phenyl-1,4-phenyl)-4-phenyl-1,2,4-triazole has been investigated using different scanning calorimetry (DSC) and thermogravimetry (TG).
Gebben, B. +2 more
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Synthesis of some New 1,2,4-Triazole derivatives [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2013 In the present work, compound 3-arylidene amino-5-methyl-1,2,4-triazole (IIIa-c), required as starting material obtained in one-pot reaction by condensing 5-methyl-3-amino-1,2,4-triazole with different aromatic aldehydes.
Ibtehal Kahtan Abdullah
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Normal and reversed phase high performance liquid chromatography of some new 1, 2, 4-triazole derivatives [PDF]
, 2003 The retention behaviour and separation ability of normal and reversed phase HPLC with one non-polar and two polar mobile phases, have been studied by measuring the retention constants of a series of newly synthesized 1,2,4-triazole derivatives.
Ačanski Marijana M. +2 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Aim. To study the effect of 4-benzylideneamino-5-phenyl-4H-1,2,4-triazole-3-thiones and salts of 2-(4-amino-5-phenyl-4H-1,2,4-triazole-3-yltio)acetic acid on central component of nociceptive system on condition of thermal stimulation of limbs of rats ...
Ye. S. Pruhlo
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C-Glycosyl 1,2,4-triazoles: Synthesis of the 3-β-d-glucopyranosyl-1,5-disubstituted and 5-β-d-glucopyranosyl-1,3-disubstituted variants [PDF]
, 2017 K
Páhi, András +2 more
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1,2,4-Triazoles. IV. Tautomerism of 3,5-disubstituted 1,2,4-triazoles.
Chemical and Pharmaceutical Bulletin, 1975 Tautomerism of ten 3, 5-disubstituted 1, 2, 4-triazoles, which can exist in three tautomeric forms, has been studied. The nuclear magnetic resonance (NMR) and ultraviolet (UV) spectra of these 1, 2, 4-triazoles were compared with those of the N-methyl derivatives, which are the model compounds of the three kinds of tautomeric forms.
SEIJU KUBOTA, MASAYUKI UDA
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Pharmacological aspects of application of 1,2,4-triazole-3-thiol furan derivatives
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Introduction. Nowadays 1,2,4-triazole-3-thiol furan derivatives have established themselves as a separate class of promising bioactive compounds. Presented substance is practically non-toxic and exhibits various kinds of pharmacological activity.
O. A. Bihdan +3 more
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