Thiazole, oxadiazole, and carboxamide derivatives of artemisinin are highly selective and potent inhibitors of Toxoplasma gondii. [PDF]
J Med Chem, 2010 Hencken CP +7 more
europepmc +1 more source
Endoperoxides as antimalarials and the application of singlet oxygen to the synthesis of key intermediaries en route to synthetic 1,2,4-trioxanes and synthesis and biological activity of minor groove binding-artemisinin conjugates [PDF]
La Pensée, Louise Josephine Ilse
core +1 more source
Next-Generation Antimalarial Drugs: Hybrid Molecules as a New Strategy in Drug Design. [PDF]
Drug Dev Res, 2010 Muregi FW, Ishih A.
europepmc +1 more source
The antimalarial trioxaquine DU1301 alkylates heme in malaria-infected mice. [PDF]
Antimicrob Agents Chemother, 2008 Bousejra-El Garah F +4 more
europepmc +1 more source
Investigating the antimalarial action of 1,2,4-trioxolanes with fluorescent chemical probes. [PDF]
J Med Chem, 2011 Hartwig CL +5 more
europepmc +1 more source
Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine. [PDF]
J Med Chem, 2012 Slack RD +8 more
europepmc +1 more source
A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models. [PDF]
J Med Chem, 2016 Spangler B +7 more
europepmc +1 more source
Development of a new synthetic route to antimalarial 1,2,4-trioxanes, 1,2,4-trioxepanes and rational design of orally bioavailable tetraoxanes [PDF]
Amewu, Richard Kwamla
core +1 more source
In vitro activities of trioxaquines against Schistosoma mansoni. [PDF]
Antimicrob Agents Chemother, 2009 Boissier J +3 more
europepmc +1 more source
In vitro and in vivo activities of synthetic trioxolanes against major human schistosome species. [PDF]
Antimicrob Agents Chemother, 2007 Xiao SH +7 more
europepmc +1 more source