Results 91 to 100 of about 300,590 (210)

Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration

Nature Communications, 2020
Vitamin D is a precursor of the steroid hormone 1,25-dihydroxyvitamin D3, and its deficiency is associated with many adverse health outcomes. Here, Revez et al.
Joana A. Revez, Tian Lin, Zhen Qiao, Angli Xue, Yan Holtz, Zhihong Zhu, Jian Zeng, Huanwei Wang, Julia Sidorenko, Kathryn E. Kemper, Anna A. E. Vinkhuyzen, Julanne Frater, Darryl Eyles, Thomas H. J. Burne, Brittany Mitchell, Nicholas G. Martin, Gu Zhu, Peter M. Visscher, Jian Yang, Naomi R. Wray, John J. McGrath   +20 more
doaj   +1 more source

The 24-hydroxylation of 1,25-dihydroxyvitamin D3.

Journal of Biological Chemistry, 1977
The production of 1,24,25-trihydroxyvitamin D3 in vivo in vitamin D-deficient rats has been demonstrated from either 25-hydroxyvitamin D3 or 1,25-dihydroxyvitamin D3. The stereochemical configuration of the hydroxyl on the 24 position of 1,24,25-trihydroxyvitamin D3 has also been unambiguously established to be R.
Y, Tanaka, L, Castillo, H F, DeLuca
openaire   +2 more sources

Human male gamete endocrinology: 1alpha, 25-dihydroxyvitamin D3 (1,25(OH)2D3) regulates different aspects of human sperm biology and metabolism

Reproductive Biology and Endocrinology, 2009
Background A wider biological role of 1alpha,25-Dihydroxyvitamin D3 (1,25(OH)2D3), the active metabolite of vitamin D3, in tissues not primarily related to mineral metabolism was suggested. Recently, we evidenced the ultrastructural localization the 1,25(
Perrotta Ida, Middea Emilia, Guido Carmela, Aquila Saveria, Bruno Rosalinda, Pellegrino Michele, Andò Sebastiano   +6 more
doaj   +1 more source

Early 1,25-dihydroxyvitamin D3-glycosides supplementation: an efficient feeding strategy against bacterial chondronecrosis with osteomyelitis lameness in broilers assessed by using an aerosol transmission model

Journal of Applied Poultry Research
SUMMARY: Bacterial chondronecrosis with osteomyelitis (BCO) lameness is a leg disorder in broilers leading to huge economic losses, food safety concerns, and animal welfare issues in the poultry industry.
Andi Asnayanti, Khawla Alharbi, Anh D.T. Do, Layla Al-Mitib, Kathrin Bühler, Jan Dirk Van der Klis, Javier Gonzalez, Michael T. Kidd, Adnan A.K. Alrubaye   +8 more
doaj   +1 more source

The effects of 1,25-dihydroxyvitamin D3 on rat primary astrocytes [PDF]

, 2013
Thesis (M.A.)--Boston UniversityVitamin D, more specifically 1,25-dihydroxyvitamin D3, has received increasing attention over the past several years for its widespread effects on the genome. This study hypothesized that 1,25-dihydroxyvitamin D3 decreases
Curletto, Bryon Joseph
core   +1 more source

1,25-Dihydroxyvitamin D3 inhibits Na(+)-dependent phosphate transport in osteoblastic cells

, 1993
In the present work we investigated the influence of vitamin D3 metabolites on Na(+)-dependent phosphate (Pi) transport in the clonal osteoblastic cell line UMR-106.
K. V. Luong, L. H. Ye, C. R. Kleeman, J. Green, C. Chaimovitz   +4 more
core   +1 more source

Acute effect of 1,25-dihydroxyvitamin D3, prednisone, and 1,25-dihydroxyvitamin D3 plus prednisone on serum osteocalcin in normal individuals

Journal of Bone and Mineral Research, 1991
Abstract Suppression of osteoblastic function plays an important pathogenic role for the development of glucocorticosteroid-induced osteoporosis. Serum osteocalcin (OC) is a sensitive marker of bone formation. The diurnal rhythm in serum OC can be changed by administration of single doses of either 1,25-(OH)2D3 or prednisone.
H K, Nielsen, K, Brixen, M, Kassem, L, Mosekilde   +3 more
openaire   +2 more sources

1,25-Dihydroxyvitamin D3 alleviates hyperandrogen-induced ferroptosis in KGN cells. [PDF]

Hormones (Athens), 2023
Jiang Y, Yang J, Du K, Luo K, Yuan X, Hua F.   +5 more
europepmc   +1 more source

Low levels of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 in patients with newly diagnosed type 1 diabetes

, 2005
An epidemiological retrospective study and a recent prospective study from Finland have both concluded that vitamin D3 supplementation at birth protects individuals from type 1 diabetes later in life.
Montemari A. L. e, Crinò, A, Coppolino G. e, M. L. Bizzarri, C. Cappa, Leomanni, C, Costanza F. e, Cavallo MG, Spera S., Anguissola G. B. e, De Mattia, Khazrai, M, Manca Bitti, Picardi, A, M. Pitocco, Pozzilli, P, Cassone Faldetta M. R., Valente, L, Schiaffini R., Cherubini, V, Corbi S., Manfrini, S, Suraci C, D. Ghirlanda, Cervoni M., Visalli N, Guglielmi C. e, Patera P., Lauria A., Cipolloni L., Matteoli M. C.   +30 more
core   +1 more source

The metabolism and mechanism of action of 1,25-dihydroxyvitamin D3

Kidney International, 1986
Much has been learned about the formation of the active metabolite of vitamin D3, 1,25-dihydroxyvitamin D3. Information concerning its formation and catabolism has allowed a clear understanding of factors involved in the maintenance of plasma concentrations of the hormone.
openaire   +2 more sources