Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System. [PDF]
Front Neurosci, 2019 Faye PA +7 more
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Mitigating bisphenol A-induced apoptosis in KGN cells: the therapeutic role of 1,25-dihydroxyvitamin D3 through upregulation of PGC-1α expression and inhibition of the mitochondrial cytochrome c pathway. [PDF]
Hormones (Athens)Tang L, Du K, Luo K, Wang L, Hua F.
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1,25-Dihydroxyvitamin D<sub>3</sub> Suppresses Prognostic Survival Biomarkers Associated with Cell Cycle and Actin Organization in a Non-Malignant African American Prostate Cell Line. [PDF]
Biology (Basel)Johnson JR +16 more
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1,25‐Dihydroxyvitamin D3 and myeloproliferative syndromes
American Journal of Hematology, 1990We treated three patients with IM and five with IT, with 1,25(OH) 2 vit D3 at a daily dose of 1.5 to 3 μg p.o. for at least 12 months. A dairy product-free diet was prescribed for the whole treatment period. Bone marrow aspirate and biopsy were evaluated at diagnosis and every 6 months thereafter.
P. FOA +8 more
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Phosphatemic action of 1,25-dihydroxyvitamin D3
American Journal of Physiology-Legacy Content, 1975The action of a single intraperitoneal injection of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) was investigated in thyroparathyroidectomized (TPTX) vitamin D-deficient phosphate-depleted rats. After 14 h, plasma inorganic phosphorus (Pi) was significantly greater in animals receiving 1,25(OH)2D3 than in D-deficient controls, but urinary Pi excretion was ...
T H, Steele +5 more
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Immunomodulatory effects of 1,25-dihydroxyvitamin D3
Current Opinion in Nephrology and Hypertension, 1995The activated form of vitamin D, 1,25-dihydroxyvitamin D3, has not only a central role in bone and calcium metabolism, but also has important general effects on cell proliferation and differentiation. Moreover, 1,25-dihydroxyvitamin D3 behaves as a paracrine factor in the immune system as it can be produced by monocytes and has potent actions on all ...
K, Casteels +3 more
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Genomic Actions of 1,25-dihydroxyvitamin D3
The Journal of Nutrition, 1995Recent studies have identified a heterodimer of the vitamin D receptor (VDR) and the retinoid X receptor (RXR) as the active complex for mediating positive transcriptional effects of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], the active hormonal form of vitamin D.
G K, Whitfield +6 more
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Metabolism of 1,25-dihydroxyvitamin D3
Physiological Reviews, 1984Synthesis of 1,25(OH)2D3 is controlled by numerous factors. The major ones, however, are the circulating amounts of parathyroid hormone (the secretion of which is stimulated by low serum calcium), serum or extracellular fluid phosphorus concentrations, circulating levels of 1,25(OH)2D3 itself, and perhaps serum calcium directly.
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Effect of 1,25 Dihydroxyvitamin D3 on Insulin Secretion
Diabetes, 1981Recent autoradiographic studies demonstrated that Bcells concentrate 1,25 (OH)2 D3 in their nuclei, suggesting a genomic action on B-cell function. This study was undertaken to investigate the effects of 1,25 (OH)2 D3 on insulin secretion in vitamin D-deficient rats.
S A, Clark, W E, Stumpf, M, Sar
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A new fluoro analog of 1,25-dihydroxyvitamin D3, i.e., 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3, has been compared with the native hormone, 1,25-dihydroxyvitamin D3, in its biological potency, duration of action, and binding to the vitamin D transport protein and intestinal receptor protein.
Y, Tanaka +3 more
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