Results 171 to 180 of about 300,590 (210)

1,25-dihydroxyvitamin D3 in childhood hepatic osteodystrophy

The Journal of Pediatrics, 1979
Osteodystrophy frequently accompanies severe childhood hepatobiliary disease. Proposed causes include malabsorption of vitamin D and calcium, and diminished 25-hydroxylation of vitamin D. Two children, ages 23 and 35 months, with radiographic and biochemical evidence of rickets with extrahepatic biliary atresia, were treated with 1,25-dihydroxyvitamin ...
J E, Heubi, R C, Tsang, J J, Steichen, G M, Chan, I W, Chen, H F, DeLuca   +5 more
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Target cells for 1,25 dihydroxyvitamin D3 in the pancreas

Cell and Tissue Research, 1980
Mature rats raised on a vitamin D deficient diet were injected with tritium labeled, 1,25 dihydroxyvitamin D3. Concentration of radioactivity, which is prevented by pretreatment with unlabeled 1,25 dihydroxyvitamin D3, is found in nuclei of cells that are centrally located in pancreatic islets.
S A, Clark, W E, Stumpf, M, Sar, H F, DeLuca, Y, Tanaka   +4 more
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1,25-Dihydroxyvitamin D3– a hormone with immunomodulatory properties

Zeitschrift für Rheumatologie, 2000
The active vitamin D metabolite, 1,25-dihydroxyvitamin D3[1,25-(OH)2D3], exerts immunosuppressive activity. At a cellular and molecular level, the hormone preferentially targets helper T cell activity (Th1) by inhibiting the secretion of both IL-2 and IFN-gamma by Th1 and by suppressing the secretion pro-Th1 cytokine IL-12 by antigen-presenting cells ...
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1,25-Dihydroxyvitamin D3 in the pathogenesis and treatment of osteoporosis

Osteoporosis International, 1997
There is abundant evidence that the vitamin D system plays a role in the pathogenesis of osteoporosis, being more likely to play a more direct role in age-related osteoporosis than in other forms. The rationale behind the value of using these compounds for the treatment of osteoporosis has been presented. Finally, the approach of new analogs that might
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Evaluation of a photolabile derivative of 1,25-dihydroxyvitamin D3 as a photoaffinity probe for 1,25-dihydroxyvitamin-D3 receptor in chick intestinal cytosol

Biochemical and Biophysical Research Communications, 1985
We evaluated the viability of 1 alpha, 25-dihydroxyvitamin D3-3 beta-[N-(4-azido-2-nitrophenyl)glycinate] (1,25-(OH)2-D3-ANG), an analog of 1 alpha, 25-dihydroxyvitamin D3 (1,25-(OH)2-D3) as a photoaffinity probe for 1,25-(OH)2-D3 receptor in chick intestinal cytosol.
R, Ray, S, Rose, S A, Holick, M F, Holick   +3 more
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Properties and compartmentalization of the testicular receptor for 1,25-dihydroxyvitamin D3

Journal of Steroid Biochemistry, 1985
Adult rat testis contains a specific, high-affinity, low-capacity binding protein for 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) with properties similar to 1,25-(OH)2D3 receptors in other tissues. The receptor sediments at 3.5 +/- 0.2 S20,w in high-salt sucrose density gradients, but aggregates in low-salt gradients.
F O, Levy, L, Eikvar, N H, Jutte, A, Frøysa, S M, Tvermyr, V, Hansson   +5 more
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1,25-DIHYDROXYVITAMIN D3 AND MYELOFIBROSIS

The Lancet, 1984
D, McCarthy, J, Hibbin, E, Matutes, P, Daniel, D, Catovsky, J M, Goldman   +5 more
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1,25-DIHYDROXYVITAMIN D3 RECEPTORS IN CANCER

The Lancet, 1980
J A, Eisman, T J, Martin, I, MacIntyre
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Influence of 1,25-dihydroxyvitamin D3 on cultured osteogenic sarcoma cells: correlation with the 1,25-dihydroxyvitamin D3 receptor.

Cancer research, 1984
We have characterized the effects of the steroid hormone 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] on a series of rat osteogenic sarcoma cell lines of increasing osteoblastic-like nature (ROS 24/1, ROS 2/3, and ROS 17/2.8). When these cells were grown in monolayer culture in the presence of 10 nM 1,25-(OH)2D3, there was a dramatic and selective ...
S, Dokoh, C A, Donaldson, M R, Haussler
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1,25-Dihydroxyvitamin D3 metabolism

Archives of Biochemistry and Biophysics, 1978
M.L. Ribovich, H.F. DeLuca
openaire   +1 more source