Results 61 to 70 of about 300,590 (210)

Association Between Genetically Predicted 25‐Hydroxyvitamin D and Type 2 Diabetes Risk in South Asians: An Exploratory Two‐Sample Mendelian Randomization Study

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
Using two‐sample Mendelian randomization, we found no statistically significant association between genetically predicted 25‐hydroxyvitamin D and Type 2 diabetes risk in South Asians. However, the limited exposure GWAS, three‐instrument set, exploratory instrument threshold, and possible sample overlap warrant cautious interpretation and larger South ...
Adina Zaka   +5 more
wiley   +1 more source

Novel mechanisms in the regulation of 5-lipoxygenase gene expression by 1,25-dihydroxyvitamin D3 and transforming growth factor ß [PDF]

open access: yes, 2004
Die 5 Lipoxygenase (5 LO) ist das Schlüsselenzym in der Synthese von Leukotrienen. Sie wird auf transkriptioneller und posttranskriptioneller Ebene reguliert.
Seuter, Sabine
core  

Lower placental 25-hydroxyvitamin D3 (25(OH)D3) and higher placental CYP27B1 and 25(OH)D3 ratio in preterm birth

open access: yesJournal of Nutritional Science, 2020
Neonatal mortality rates in Indonesia are still at an alarming rate, with preterm birth as one of the causes. Nutritional deficiencies such as low level of vitamin D is suspected to be the risk factors of preterm birth but still a little knowledge about ...
Rima Irwinda, Biancha Andardi
doaj   +1 more source

Klotho Deficiency Impairs Distal Potassium Homeostasis Through mTORC1‐Dependent Suppression of ROMK

open access: yesActa Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT Aim Hyperkalemia is prevalent in the elderly, and underlying molecular mechanisms remain incompletely understood. We hypothesized that Klotho deficiency, a feature of aging, impairs renal potassium homeostasis and contributes to hyperkalemia. Methods Klotho heterozygous knockout (KLhet) mice, characterized by reduced Klotho levels, were used ...
Wakako Kawarazaki   +6 more
wiley   +1 more source

Função dos hormônios tireoideos e da 1,25(OH)2 vitamina D3 em células testiculares de ratos imaturos [PDF]

open access: yes, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2015.A espermatogênese, processo que ocorre nos túbulos seminíferos (TS), é controlada por uma rede de fatores ...
Zanatta, Ana Paula
core  

Vitamin D: Physiology, Pharmacology and Clinical Evidence for Supplementation—A Narrative Review

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT Vitamin D is a nutrient and prohormone obtained from diet and supplements and synthesized in the skin. It is essential for calcium and phosphate homeostasis and skeletal health and influences multiple extra‐skeletal processes, yet deficiency remains common worldwide.
Jyrki K. Virtanen
wiley   +1 more source

Vitamin D3 metabolite ratio as an indicator of vitamin D status and its association with diabetes complications

open access: yesBMC Endocrine Disorders, 2020
Background Vitamin D deficiency is diagnosed by total serum 25-hydroxyvitamin D (25(OH)D) concentration and is associated with poor health and increased mortality; however, some populations have low 25(OH) D concentrations without manifestations of ...
Lina H. M. Ahmed   +6 more
doaj   +1 more source

Vitamin D3 alters macrophage phenotype and endosomal trafficking markers in dairy cattle naturally infected with Mycobacterium avium subsp. paratuberculosis

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Macrophages are important host defense cells in ruminant paratuberculosis (Johne’s Disease; JD), a chronic enteritis caused by Mycobacterium avium subsp. paratuberculosis (MAP).
Taylor L. T. Wherry   +5 more
doaj   +1 more source

Serum Vitamin D Levels at Birth Are Not Associated With the Formation of Interglobular Dentin in Deciduous Teeth of Modern New Zealand Children

open access: yesAmerican Journal of Biological Anthropology, Volume 191, Issue 2, October 2026.
ABSTRACT Interglobular dentin (IGD) has been used as a biomarker for vitamin D deficiency (VDD) in past populations. However, an evidence‐based threshold for the levels of serum vitamin D associated with IGD occurrence has not been established. Here, we explore the association between perinatal serum vitamin D levels, presence of IGD, and biological ...
Anne Marie Sohler‐Snoddy   +6 more
wiley   +1 more source

Pengaruh Panhisterektomi dan Konsumsi Suplemen 1,25-Dihidroksivitamin D3 Selama 1,5 Bulan terhadap Retensi Kalsium pada Tikus Wistar

open access: yesJurnal Veteriner, 2010
The objective of the research was to study the effect of panhisterectomy and 1,25-dihydroxyvitamin D3supplement consumption for 1.5 months on Ca retention of Wistar rats fed with casein.
Hartiningsih -   +2 more
doaj  

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