Results 141 to 150 of about 8,138 (214)

Design, Synthesis, <i>In Vitro</i> Evaluation, Multitargeted Molecular Docking, and <i>In Silico</i> Analysis of Some Azo-Linked 1,3,4-Thiadiazole and 1,2,4-Triazole Heterocyclic Hybrids as Potent Antitubercular Agents. [PDF]

ACS Omega
Panigrahi D, Sahu SK.
europepmc   +1 more source

Understanding the synergistic interaction between a 1,3,4-thiadiazole derivative and amphotericin B using spectroscopic and theoretical studies. [PDF]

Sci Rep
Ślusarczyk L, Rząd K, Niedzielski G, Gurba M, Chavez J, Ceresa L, Kimball J, Gryczyński I, Gryczyński Z, Gagoś M, Hooper J, Matwijczuk A.   +11 more
europepmc   +1 more source

Identification of 5-amino-1,3,4-thiadiazole appended isatins as bioactive small molecules with polypharmacological activities. [PDF]

RSC Med Chem
Azam U, Humayun WA, Avathan Veettil AK, Liu Y, Hastürk O, Jiang M, Sievers S, Wu P, Naseer MM.   +8 more
europepmc   +1 more source

Design, Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel 1,3,4-Thiadiazole Derivatives Targeting Both Aldose Reductase and α-Glucosidase for Diabetes Mellitus. [PDF]

ACS Omega
Kaya B, Acar Çevik U, Necip A, Duran HE, Çiftçi B, Işık M, Soyer P, Bostancı HE, Kaplancıklı ZA, Beydemir Ş.   +9 more
europepmc   +1 more source

Synthesis of 1,3,4-thiadiazole amide derivatives

1,3,4-Thiadiazoles are important five-membered heterocyclic compounds found in the structures of various drugs and possessing antimicrobial, antifungal [1], anticancer [2], insecticidal [3], antiviral [4], and herbicidal [5] biological activities. [...]
Kučinskas, Augustas, Anusevičius, Kazimieras, Mickevičius, Vytautas   +2 more
openaire   +1 more source

Design, Synthesis, Anticancer Screening, and Mechanistic Study of Spiro-N-(4-sulfamoyl-phenyl)-1,3,4-thiadiazole-2-carboxamide Derivatives. [PDF]

Int J Mol Sci
El-Saghier AM, Hashem H, Maher SA, Enaili SS, Alkhammash A, Bräse S, Aziz HA.   +6 more
europepmc   +1 more source

Synthesis of Hybrid Molecules with Imidazole-1,3,4-thiadiazole Core and Evaluation of Biological Activity on Trypanosoma cruzi and Leishmania donovani. [PDF]

Molecules
Mijoba A, Parra-Giménez N, Fernandez-Moreira E, Ramírez H, Serrano X, Blanco Z, Espinosa S, Charris JE.   +7 more
europepmc   +1 more source

Antimicrobial and antiurease activities of newly synthesized morpholine derivatives containing an azole nucleus [PDF]

core   +1 more source

Cooperativity of ESPT and Aggregation-Induced Emission Effects-An Experimental and Theoretical Analysis of a 1,3,4-Thiadiazole Derivative. [PDF]

Int J Mol Sci
Budziak-Wieczorek I, Kaczmarczyk D, Rząd K, Gagoś M, Stepulak A, Myśliwa-Kurdziel B, Karcz D, Starzak K, Burdziński G, Srebro-Hooper M, Matwijczuk A.   +10 more
europepmc   +1 more source

In Silico Screening of 1,3,4-Thiadiazole Derivatives as Inhibitors of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2). [PDF]

Curr Issues Mol Biol
Ewell SM, Burton H, Mochona B.
europepmc   +1 more source