Novel [1,3,4]Thiadiazole[3,2-a]pyrimidin-5-ones as Promising Biofilm Dispersal Agents against Relevant Gram-Positive and Gram-Negative Pathogens. [PDF]
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Synthesis and antiproliferative potency of 1,3,4-thiadiazole and 1,3-thiazolidine-4-one based new binary heterocyclic molecules: <i>in vitro</i> cell-based anticancer studies. [PDF]
RSC Med ChemMaji A +9 more
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Synthesis and biological evaluation of novel substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1-b] [1,3,4] thiadiazole derivatives [PDF]
European Journal of Medicinal Chemistry, 2014 A new series of N-[5-(4-(alkyl/aryl)-3-nitro-phenyl)-[1,3,4-thiadiazol-2-yl]-2,2-dimethyl-propionamide 4(ael) and 6-(4-Methoxy-phenyl)-2-(4-alkyl/aryl)-3-nitro-phenyl)-Imidazo [2,1-b] [1,3,4] thiadiazole 6(ael) were synthesized starting from 5-(4-Fluoro ...
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Nine 1,3,4-thiadiazoles showed an antiviral action against Mengo virus; four of them were also active against vaccinia virus and one against fowl plague virus. Investigations with Mengo virus revealed plaque reduction, inhibition of the cytopathic effect and depression of virus multiplication, with the maximum activity after substance addition from 0–2
Marion Tonew, Elke Klimke
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Synthesis and antifungal activity of thiadiazole-functionalized chitosan derivatives [PDF]
Carbohydrate Research, 2013 A groups of novel water soluble chitosan derivatives containing 1,3,4-thiadiazole group were synthesized including 1,3,4-thiadiazole (TPCTS), 2-methyl-1,3,4-thiadiazole (MTPCTS), and 2-phenyl-1,3,4-thiadiazole (PTPCTS).
Qing Li, Jianming Ren, Guodong Gu
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Solid-Phase Synthesis of 1,3,4-Thiadiazole Derivatives via Desulfurative Cyclization of Thiosemicarbazide Intermediate Resin [PDF]
ACS Combinatorial Science, 2016 A 1,3,4-thiadiazole library was constructed by solid-phase organic synthesis. The key step of this solid-phase synthesis involves the preparation of polymer-bound 2-amido-5-amino-1,3,4-thiadiazole resin by the cyclization of thiosemicarbazide resin using
Seung-Ju Yang, Young-Dae Gong
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Abstract The microwave spectra of 1, 3, 4-thiadiazole (I) and [ 34 S] 1, 3, 4-thiadiazole (II) have been recorded in the 15,000–30,000 Mc/sec region. Twelve and ten transitions, respectively, were assigned. The rotational constants of (I) are, A = 8907.51 ± 0.10, B = 5569.27 ± 0.02, and C = 3424.80 ± 0.03 Mc/sec. For (II), A = 8908.15 ± 0.20,
Børge Bak +4 more
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Synthesis of 1,3,4-thiadiazole oligomers
Journal of the Chemical Society, Perkin Transactions 1, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
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Copper(II) complexes of 2-amino-1,3,4-thiadiazole and 2-ethylamino-1,3,4-thiadiazole
Transition Metal Chemistry, 1982Some copper(II) complexes of 2-amino-1,3,4-thiadiazole (atz) and 2-ethylamino-1,3,4-thiadiazole (eatz) have been prepared and studied by electronic, i.r. and e.p.r. spectra and by magnetochemical and conductometric methods. The CuX2 · atz (X=Cl, Br) and CuCl2 · eatz complexes are presumably six-coordinate with bridging ligand molecules and ...
Antonio C. Fabretti +2 more
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Microwave spectra of isotopic 1,3,4-thiadiazoles. Molecular structure of 1,3,4-thiadiazole
Journal of Molecular Spectroscopy, 1966Abstract The microwave spectra of 2-D-, 2-13C-, and 3-15N-1,3,4-thiadiazole, C2H2N2S, were assigned and combined with earlier measurements to give a substitution structure of 1,3,4-thiadiazole. The molecule is planar with the following structural parameters: S,C=1.721A C,N=1.302A N,N=1.371A C,H=1.077A The result is ...
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