SELENIUM HETEROCYCLES XXXX [I] SYNTHESES OF 4- (2-PYRAZINYL) - 1, 2, 3: SELENADIAZOLE AND 4- (2-PYRAZILYL)' - l,2,3- THIADIAZOLE [PDF]
Journal of Sciences, Islamic Republic of Iran, 1990 Reaction of thionyl chloride with 2-acetyl-1- benzenesulfonylpyrrole semicarbazone (6 c) gave 4 - (1- benzenesulfonyl-2 - pyrrolyl) - 1, 2, 3 -thiadiazole (lc). Selenium dioxide oxidation of 2-acetylpyrazine semicarbazone (10) in acetic acid afforded 4- (
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Indian Journal of Health Sciences and Biomedical Research KLEU, 2019 INTRODUCTION: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used as analgesics and antipyretics in the treatment of pain, fever, and rheumatoid arthritis. Major side effect with treatment of NSAIDs is gastric irritation.
Manjula K Chikkamath +2 more
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Chemical and Pharmaceutical Bulletin, 1958 1) 1-(5-R-1, 3, 4-Thiadiazol-2-yl)-3-methyl-4-R'-2-pyrazolin-5-one (R'=H, iso-C3H7) (III) were synthesized starting with 2-hydrazino-5-R-1, 3, 4-thiadiazole (I : R=CH3, C2H5, n-C3H7, iso-C4H9, C6H5), and reacting them with ethyl acetoacetate or ethyl 3-acetyliso-valerate to form 5-R-1, 3, 4-thiadiazolylhydrazone (II).
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Synthesis, Docking and Acetylcholinesterase Inhibitory Evaluation of 1,3,4-Thiadiazole Derivatives as Potential Anti-Alzheimer Agents [PDF]
Pharmaceutical SciencesBackground: According to the cholinergic hypothesis for Alzheimer’s disease, potentiation of cholinergic neurotransmission is one of the best strategies for combating dementia.
Ahmad Mohammadi-Farani +5 more
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Diethyl {(4-methoxyphenyl)[5-(4-nitrophenyl)-1,3,4-thiadiazol-2-ylamino]methyl}phosphonate
Acta Crystallographica Section E, 2008 The title compound, C20H23N4O6PS, was synthesized by the reaction of N-(4-methoxybenzylidene)-5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine and diethyl phosphite. The thiadiazole and nitro-substituted phenyl rings in the molecule are approximately coplanar,
Li-He Yin +4 more
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Synthesis and cytotoxic activity evaluation of some new 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4- triazole derivatives attached to phthalimide. [PDF]
Res Pharm Sci, 2021 Hassanzadeh F +3 more
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N-[4-Acetyl-5-(2-methylprop-1-enyl)-5-(2-p-tolylpropyl)-4,5-dihydro-1,3,4-thiadiazol-2-yl]acetamide
Acta Crystallographica Section E, 2009 The title heterocyclic compound, C20H27N3O2S, was synthesized from 2-(4-methylcyclohex-3-enyl)-6-methylhepta-2,5-dien-4-one, which was isolated from the essential oil Cedrus atlantica.
Noureddine Mazoir +5 more
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(E)-N-(4-Chlorobenzylidene)-5-(4-methylphenyl)-1,3,4-thiadiazol-2-amine
Acta Crystallographica Section E, 2011 The title compound, C16H12ClN3S, was synthesized by the reaction of 5-(4-methylphenyl)-1,3,4-thiadiazol-2-amine and 4-chlorobenzaldehyde. The thiadiazole ring is essentially planar with mean deviation of 0.0042 Å.
Peng Yu +4 more
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Antimicrobial activity of 1, 3, 4-thiadiazole derivatives: a recent review
Journal of Applied Pharmaceutical Research, 2018 A few five members’ aromatic systems having three hetero-atoms at symmetrical positions, for example, thiadiazoles have been considered broadly attributable to their intriguing pharmacological properties. These thiadiazole derivatives are the heterocyclic compound which contains the five member ring along with nitrogen and sulfur atoms.
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Proceedings of the International Conference on Applied Innovations in ITOwing to the rapid rise in antibiotic resistance, infectious diseases have become serious threat to public health. There is an urgent need to develop new antimicrobial agents with diverse chemical structures and novel mechanisms of action to overcome the
Wejdan Khaled Harat +1 more
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