Results 161 to 170 of about 15,802 (202)
Ultrasonics Sonochemistry, 2009 Novel substituted 1,3,4-thiadiazole and bi(1,3,4-thiadiazole) were synthesized from reaction of 1-methyl-5-oxo-3-phenyl-2-pyrazolin-4-thiocarbox-anilide with a series of different hydrazonyl halides or N,N'-diphenyl-oxalodihydrazonoyl dichloride. The reactions were carried out under both conventional and ultrasonic irradiation conditions.
Naglaa M Abd El-Rahman +2 more
exaly +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Tetrahedron, 1968
Abstract Some 2-aryl-5-chloro-1,3,4-thiadiazoles (I; X = Cl) were treated with several nucleophilic agents in different solvents. Displacement of chlorine by piperidine was chosen for a kinetic study in ethanol and in benzene, in the temperature range 30–60°.
A. Alemagna, T. Bacchetti, P. Beltrame
openaire +1 more source
Abstract Some 2-aryl-5-chloro-1,3,4-thiadiazoles (I; X = Cl) were treated with several nucleophilic agents in different solvents. Displacement of chlorine by piperidine was chosen for a kinetic study in ethanol and in benzene, in the temperature range 30–60°.
A. Alemagna, T. Bacchetti, P. Beltrame
openaire +1 more source
Synthesis of Several Mesoionic 1,3,4-Thiadiazoles
Journal of Pharmaceutical Sciences, 1965Several mesoionic 1,3,4-thiadiazoles, more properly termed anhydro-4-phenyl-5-substituted-2-thio-1-thia-3,4-diazolinium thiols, have been synthesized. Physical constants for the compounds have been determined and recorded. Preliminary screening against selected microorganisms indicated some useful inhibitory activity in vitro .
T G, Stewart, L B, Kier
openaire +2 more sources
Kristallin‐flüssige 1,3,4‐Thiadiazole. I. Biphenyl‐ und terphenylanaloge 1,3,4‐Thiadiazole
Journal für Praktische Chemie, 1980Liquid Crystalline 1,3,4‐Thiadiazoles. I. Biphenyl‐ and Terphenyl Analogous 1,3,4‐ThiadiazolesThe synthesis of disubstituted 1,3,4‐ and 1,2,4‐thiadiazoles and 1,3,4‐oxadiazoles is described and their melting and clearing points are investigated. The influence of the heterocyclic ring system on the formation of crystalline liquid phases is discussed.
K. Dimitrowa +3 more
openaire +1 more source
Kristallin‐flüssige 1,3,4‐Thiadiazole. II [1]. 1,3,4‐Thiadiazole mit Cyclohexanstrukturfragmenten
Journal für Praktische Chemie, 1989Liquid Crystalline 1,3,4‐Thiadiazoles. II. 1,3,4‐Thiadiazoles with CyclohexanefragmentsPreparation and liquid crystalline properties of disubstituted 1,3,4‐thiadiazoles (1 and 2) are described. The mesomorphic behaviour of the title compounds is compared with their benzoate analogues. The dielectric anisotropy of these compounds is negative.
W. Schäfer +4 more
openaire +1 more source
1,3,4-Thiadiazole: A Versatile Pharmacophore of Medicinal Significance
Medicinal Chemistry, 2023Abstract: The 1,3,4-thiadiazole nucleus has attracted the attention of medicinal chemists during the last decades due to its multiple pharmacological activities, such as antiviral, anticancer, antibacterial, and anticonvulsant activity. This scaffold's structural alteration could aid in developing novel therapeutically effective drugs.
Madhu, Bala +4 more
openaire +2 more sources
1,3,4-THIADIAZOLES FROM THIOSEMICARBAZIDES
Phosphorus, Sulfur, and Silicon and the Related Elements, 1991Abstract A new method for the synthesis of 1,3,4-thiadiazoles is described. Thus condensation of 4-methyl-4phenyl-3-thiosemicarbazide with an aldehyde or ketone affords 1,1-disubstituted-6-[1-(arylethylidine) amino] −2,5-dithiobiureas, rather than the anticipated 4,4-disubstituted-3-thiosemicarbazones.
John P. Scovill +3 more
openaire +1 more source
Syntheses of arylsulfonyl‐1,3,4‐thiadiazoles
Journal of Heterocyclic Chemistry, 1996AbstractReaction of sodium arylsulfinate with 2‐aryl‐5‐chloro‐1,3,4‐thiadiazole gave 2‐aryl‐5‐arylsulfonyl‐1,3,4‐thiadiazole (3) in good yield. Starting from readily available 2‐amino‐5‐benzylmercapto‐1,3,4‐thiadiazole compound 7 was obtained in three steps in moderate yield.
A. Shafiee, A. Foroumadi
openaire +1 more source
1,3,4-Thiadiazole Based Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry, 2016In recent years, researchers like medicinal chemists in the field of medicinal chemistry have widely utilized the 1,3,4-thiadiazole nucleus to investigate its biological and pharmacological effects. This heterocyclic structure has demonstrated various bioactivities such as antifungal, antimicrobial, antiviral, antileishmanial, anti-inflammatory ...
openaire +2 more sources