1,3,4-Thiadiazole and oxadiazole hetetocycles are well-known pharmacophore scaffolds, which possess wide possibility for chemical modification and identified diverse pharmacological potential.
M. I. Lelyukh
doaj +1 more source
2-(4-Fluoro-3-nitrophenyl)-6-(4-methoxyphenyl)imidazo[2,1-b]-1,3,4-thiadiazole [PDF]
The title compound, 2-(4-fluoro-3-nitrophenyl)-6-(4-methoxyphenyl)imidazo[2,1-b]-1,3,4-thiadiazole (3) was obtained by the condensation of 5-(4-fluoro-3-nitrophenyl)-[1,3,4]thiadiazol-2-ylamine (1) with 4-methoxyphenacyl bromide (2).
Balladka Kunhanna Sarojini +2 more
core +1 more source
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley +1 more source
Synthesis, Characterization and Biological activity of 1,3,4- Oxadiazole and 1,3,4- Thiadiazole Derivatives. [PDF]
Various substituted 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives have been synthesized by cyclising semicarbazone and thiosemicarbazone in presence of ferric chloride and citric acid to form 2-amino-5-substituted 1,3,4-oxadiazole and 1,3,4 ...
Smylin Ajitha Rani, S
core
A Highly Efficient Diversification of 2‑Amino/Amido-1,3,4-oxadiazole and 1,3,4-Thiadiazole Derivatives via Reagent-Based Cyclization of Thiosemicarbazide Intermediate on Solid-Phase [PDF]
A 2-amino/amido-1,3,4-oxadiazole and 1,3,4-thiadiazole library has been constructed on solid-phase organic synthesis. The key step on this solid-phase synthesis involves the preparation of polymer-bound 2-amino-1,3,4-oxadiazole and 1,3,4-thiadiazole core
Ji-Hye Choe (1463143) +3 more
core +1 more source
Freezing Out Vavilov's Rule: Temperature‐Dependent Fluorescence of a Rhodanine Dye
Anomalous fluorescence behavior of a rhodanine‐based dye is revealed: weak emission at room temperature becomes intense at 77 K. The fluorescence quantum yield strongly depends on excitation wavelength, breaking Vavilov's rule. Quantum chemical studies show a delicate interplay between bright ππ* and dark nπ* states that governs this behavior.
Ottavia Racchi +8 more
wiley +1 more source
Toward the 3rd Generation of Smart Farming: Materials, Devices, and Systems for E‐Plant Technologies
This review explores the latest developments in e‐plant technologies, which are revolutionizing smart farming by enabling real‐time monitoring of plant and environmental conditions. It covers the design, applications, and systems of e‐plant devices, detailing how they integrate data analytics to optimize agricultural practices, enhance crop yields, and
Daegun Kim +5 more
wiley +1 more source
Twenty new 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole analogs were synthetized to develop P2X7 receptor (P2X7R) inhibitors. P2X7R inhibition in vitro was evaluated in mouse peritoneal macrophages, HEK-293 cells transfected with hP2X7R (dye uptake assay), and ...
Daniel T. G. Gonzaga +16 more
doaj +1 more source
6-(4-Chlorophenyl)-2-isobutylimidazo[2,1-b][1,3,4]thiadiazole [PDF]
In the title compound, C14H14ClN3S, the imidazo[2,1-b][1,3,4]thiadiazole system is essentially planar, with a maximum deviation of 0.006 (2) Å.
D. Jagadeesh Prasad +4 more
core +1 more source
Polar Switching and Cybotactic Nematic Ordering in 1,3,4-Thiadiazole-Based Short-Core Hockey Stick-Shaped Fluorescent Liquid Crystals [PDF]
We report here the synthesis and thermotropic properties of novel short-core hockey stick-shaped liquid crystalline molecules based on the 1,3,4-thiadiazole core.
Santosh Prasad Gupta (3387977) +13 more
core +1 more source

