Results 81 to 90 of about 8,138 (214)

Some New Thiadiazole Derivatives as Corrosion Inhibitors for 1018 Carbon Steel Dissolution in Sodium Chloride Solution

International Journal of Electrochemical Science, 2011
Three new thiadiazole derivatives (TDADs), namely, (I) N-[4-phenyl-5-(p-tolylimino)-4,5-dihydro-1,3,4-thiadiazole-2-yl] benzamide, (II) 2-acetyl-4-phenyl-5-(p-tolylimino)-4,5-dihydro-1,3,4-thiadiazole, and (III) Ethyl-4-phenyl-5-(p-tolylimino)-4,5 ...
F. El-Taib Heakal, A.S. Fouda, M.S. Radwan   +2 more
doaj   +1 more source

Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole–Thiazole Hybrids as Potent Colon Cancer Inhibitors

ChemistryOpen, Volume 14, Issue 11, November 2025.
Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel, Amr S. Abouzied, Magdi E. A. Zaki, Abdulwahab Alamri, Basant Farag, Saad Alqarni, Sobhi M. Gomha   +6 more
wiley   +1 more source

Перспективи застосування гетероциклічних сполук для лікування хворих на туберкульоз легень [PDF]

, 2014
Основна причина погіршення епідемічної ситуації з туберкульозу (ТБ) полягає в зміні біологічних властивостей мікобактерій (МБТ) під впливом антимікобактеріальних препаратів (АМБП) із розвитком полі- та мультирезистентних штамів М ...
Єременчук, Інга Василівна
core  

Interfering Transposable Elements: ISXoo15 Transposase as a First‐in‐Class Antibacterial Target Against Xanthomonas oryzae pv. oryzae

Molecular Plant Pathology, Volume 26, Issue 11, November 2025.
The study identifies the previously unknown transposase ISXoo15 as an antiphytobacterial target. By constructing mutant strains, this enzyme's essential role in regulating bacterial pathogenicity and virulence is revealed. ABSTRACT Current challenges in controlling phytopathogenic bacteria lie in widespread chemical resistance, biosafety concerns, and ...
Funeng Lu, Ting Liu, Tangbing Yang, Ziming Wang, Jianzhuan Li, Chunni Zhao, Huan Wu, Deyu Hu, Baoan Song   +8 more
wiley   +1 more source

Anti‐Corrosive Covalent Iodo‐Thiadiazole Catalyst Enables Aqueous Zn─S Batteries with High Coulombic Efficiency

Advanced Materials, Volume 37, Issue 43, October 29, 2025.
In aqueous Zn–S batteries, a covalently bonded iodo–thiadiazole redox mediator suppresses parasitic I3−‐mediated Zn corrosion and enhances Zn–S redox kinetics, enabling pouch cell with a high capacity of 1398 mAh g−1 after 120 cycles. This innovative catalyst design is a leap toward practical and grid‐scale aqueous Zn–S batteries. Abstract Aqueous zinc‐
Jiahao Liu, Yujie Chen, Han Wu, Chao Ye, Shi‐Zhang Qiao   +4 more
wiley   +1 more source

Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors

Frontiers in Chemistry, 2019
Twenty new 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole analogs were synthetized to develop P2X7 receptor (P2X7R) inhibitors. P2X7R inhibition in vitro was evaluated in mouse peritoneal macrophages, HEK-293 cells transfected with hP2X7R (dye uptake assay), and ...
Daniel T. G. Gonzaga, Daniel T. G. Gonzaga, Felipe H. Oliveira, N. L. von Ranke, G. Q. Pinho, Juliana P. Salles, Murilo L. Bello, Carlos R. Rodrigues, Helena C. Castro, Hellen V. C. M. de Souza, Caroline R. C. Reis, Rennan P. P. Leme, João C. M. Mafra, Luiz C. S. Pinheiro, Lucas V. B. Hoelz, Nubia Boechat, Robson X. Faria   +16 more
doaj   +1 more source

A Drug Delivery to Improve Prognosis of Traumatic Brain Injury Mice Through Mouse‐Derived Nerve Growth Factor Coated by a Nanoparticle

CNS Neuroscience &Therapeutics, Volume 31, Issue 10, October 2025.
This study is the first to demonstrate that mNGF, when nanocrystallized, crosses the BBB more effectively in TBI mice, subsequently aiding the repair and functional recovery of the nervous system post‐injury. ABSTRACT Objective The large molecular weight and limited permeability of mouse‐derived nerve growth factor (mNGF) across the blood–brain barrier
Ruichen Zhao, Shiying Dong, Di Wu, Yu Tian, Jiangyuan Yuan, Liang Mi, Chenrui Wu, Shiao Tong, Rongcai Jiang   +8 more
wiley   +1 more source

A Second-Generation Janus Scorpionate Ligand: Controlling Coordination Modes in Iron(II) Complexes by Steric Modulation [PDF]

, 2008
The second-generation Janus scorpionate ligand [HB(mtdaMe)3−] containing methyl-mercaptothiadiazolyl (mtdaMe) heterocyclic rings and (N,N,N-) and (S,S,S-) binding pockets has been prepared. The effect of methyl substitution versus the unsubstituted first-
Gardinier, James R., Grandjean, Fernande, Gwengo, Chengeto, Lindeman, Sergey V., Long, Gary J., Silva, Rosalice M., Smith, Mark D.   +6 more
core   +1 more source

Pitting Corrosion Inhibition of Type 304 Austenitic Stainless steel by 2�Amino�5�ethyl�1,3,4�thiadiazole in Dilute Sulphuric Acid [PDF]

, 2015
The electrochemical behaviour and inhibitor protection of 2 amino 5 ethyl 1,3,4 thiadiazole (TTD) on the pitting corrosion of austenitic stainless steel (type 304) in dilute sulphuric acid solution con taminated with recrystallised sodium chloride was
Loto, C. A., Loto, R. T.
core   +1 more source

Fibrous Pb(II)‐Based Coordination Polymer Operable as a Photocatalyst and Electrocatalyst for High‐Rate, Selective CO2‐to‐Formate Conversion

Advanced Functional Materials, Volume 35, Issue 28, July 10, 2025.
A coordination polymer [Pb(tadt)]n prepared by a microwave‐assisted solvothermal method selectively reduces CO2 into formate under visible light with a high apparent quantum yield of ≈25% at 400 nm. It can function as a pre‐catalyst, along with conductive Ketjen Black, to form an active PbCO3/Pb3(CO3)2(OH)2 mixture that exhibits a high Faradaic ...
Chomponoot Suppaso, Ryosuke Nakazato, Shoko Nakahata, Yoshinobu Kamakura, Fumitaka Ishiwari, Akinori Saeki, Daisuke Tanaka, Kazuhide Kamiya, Kazuhiko Maeda   +8 more
wiley   +1 more source