Results 81 to 90 of about 18,261 (204)
Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Synthesis, Characterization and Biological activity of 1,3,4- Oxadiazole and 1,3,4- Thiadiazole Derivatives. [PDF]
, 2012 Various substituted 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives have been synthesized by cyclising semicarbazone and thiosemicarbazone in presence of ferric chloride and citric acid to form 2-amino-5-substituted 1,3,4-oxadiazole and 1,3,4 ...
Smylin Ajitha Rani, S
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Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II
European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley +1 more source
Síntese de duas novas séries de compostos com estrutura discótica contendo derivados do ácido gálico [PDF]
, 2008 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemática. Programa de Pós-Graduação em QuímicaNesta dissertação, são descritas a síntese e as propriedades térmicas de duas séries de compostos com estrutura ...
Frizon, Tiago Elias Allievi
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Frontiers in Chemistry, 2019 Twenty new 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole analogs were synthetized to develop P2X7 receptor (P2X7R) inhibitors. P2X7R inhibition in vitro was evaluated in mouse peritoneal macrophages, HEK-293 cells transfected with hP2X7R (dye uptake assay), and ...
Daniel T. G. Gonzaga +16 more
doaj +1 more source
Thiadiazole-Derived Covalent Organic Framework Macroscopic Ultralight Aerogel
Shaping covalent organic frameworks (COFs) into macroscopic objects for practical application remains a huge challenge. Herein, a new thiadiazole-derived COF macroscopic ultralight aerogel (NNS-VCOF) was prepared through acid-catalyzed aldol condensation
Haifeng Ji (780358) +8 more
core +4 more sources
Synthesis of Mesoionic 1,3,4-thiadiazoles
, 1968 Synthesis of Mesoionic 1,3,4 ...
P. B. Talukdar, S. K. Sengupta
openaire +2 more sources
Фармацевтичний журнал, 2019 Diuretics are effective drugs that are widely used in medicine, but have unwanted side effects. The derivative of thiadiazole – acetozolamide is a known diuretic.
І. V. Drapak
doaj +1 more source
Síntese de cristais líquidos isônicos e/ou discóticos contendo os heterociclos 1,2,4- E 1,3,4- oxadiazol [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.A presente dissertacao traz o estudo realizado com moleculas derivadas dos heterociclos 1,
Silva, Danilo Henrique da
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, 2017 Three novel 5-benzyl-1,3,4-thiadiazole derivatives were synthesised starting from phenylacetic acid derivatives. These compounds were characterised by NMR, HRMS and single-crystal X-ray diffraction analysis.
Yu-Wei Liu +9 more
core +1 more source