Results 61 to 70 of about 15,802 (202)

A Selective Phenyl Azo Acetate Substrate for Enhanced Carbonic Anhydrase Functional Analysis

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Carbon dioxide (CO2) sequestration is a key strategy for mitigating climate change, and biocatalytic approaches offer sustainable, cost‐effective alternatives to chemical and physical methods. Carbonic anhydrases (CAs) efficiently catalyse the reversible hydration of CO2 to bicarbonate, yet their large‐scale application is constrained by ...
Justinas Babinskas, Inga Matijošytė
wiley   +1 more source

1,3,4-THIADIAZOLE: A BIOLOGICALLY ACTIVE SCAFFOLD [PDF]

, 2014
There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, anti-inflammatory, anti allergic, antipsychotic, antimicrobial, antimycobecterial, antitumour, antiviral and antitubercular ...
Akhtar, Jawed, Osman, Gamal, Khalilullah, Habibullah, Mhmood, Danish, Khan, M. U.   +4 more
core   +1 more source

Medicinal Insights Into FLT3 Inhibitors as Anticancer Agents: Current Status and Future Direction

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Structure–activity relationship of FMS‐like tyrosine kinase 3 (FLT3) as potent anti‐cancer agents supported by biological evaluation, in silico and clinical trial studies. ABSTRACT FMS‐like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase (RTK) important for hematopoietic stem cell proliferation, differentiation, and survival.
Ankush Kumar, Pallvi Kumari, Keshav Raj Paudel, Rajwinder Kaur, Rohit Bhatia   +4 more
wiley   +1 more source

Review On Systematic Mapping Study For Synthesis Of Polymers Containing 1,3,4 Thiadiazole

Al-Kitab Journal for Pure Sciences
Due to the unique properties of a heterocyclic compound, it gained attention in the field of materials science. This study aims to provide a comprehensive synthesis of new co-polymers containing 1,3,4-thiadiazole.
Hiba Shihab Ahmed, Mostefe Mostefe Khalid Mohammed, Noor Hatem Khorsheed, Eman Mudher Esmail   +3 more
doaj   +1 more source

Antidiabetic and Cytotoxicity Studies of Novel Quinazolinone–1,3,4‐Thiadiazole Molecular Hybrids

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
ABSTRACT In the treatment of diabetes mellitus (DM), inhibition of carbohydrate‐hydrolysing enzymes, such as α‐amylase, has emerged as a promising therapeutic strategy. In the present study, a series of quinazolinone‐1,3,4‐thiadiazole molecular hybrids were designed, synthesized and biologically evaluated for their antidiabetic potential.
Prishani Kisten, Pule Seboletswe, Gobind kumar, Nontobeko Gcabashe, Neha Manhas, Ankit, Almahi Idris, Md. Shahidul Islam, René Khan, Parvesh Singh   +9 more
wiley   +1 more source

DFT calculation of the electronic properties of fluorene-1,3,4-thiadiazole oligomers [PDF]

, 2013
Thiadiazole derivatives have been widely employed in the areas of pharmaceutical, agricultural, industrial, and polymer chemistry. The electronic and molecular structures of thiadiazoles are of interest because they have an equal number of valence ...
NORMA ROSARIO FLORES HOLGUIN
core   +1 more source

Synthesis, spectroscopic characterization, X-ray crystallography, structural activity relationship and antimicrobial activity of some novel 4-(5-(10-(3-N, N-dimethylamino)propyl)-10H-phenothiazine-3-yl)-1, 3, 4-thiadiazole-2-yl) Azo dye/Schiff base derivatives

Future Journal of Pharmaceutical Sciences, 2017
In the present investigation, a series of novel 4 (5-(10-(3-(N,N-dimethylamino)propyl)-10H-phenothiazine-3-yl)-1,3,4-thiadiazo-2-yl) Azo dye/Schiff base derivatives (5a-e & 6a-j) were synthesised by performing diazotization followed by coupling reaction ...
Chandravadivelu Gopi, Vedula Girija Sastry, Magharla Dasaratha Dhanaraju   +2 more
doaj   +1 more source

Synthesis and Study of Some 4-Chlorophenoxy Methyl Substituted amido1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles from 4-Chloro phenoxy acetic acid [PDF]

مجلة التربية والعلم, 2013
: In this paper the synthesis of some substituted 1,3,4-oxadiazole, 1,3,4-thiadiazoles and 1,2,4-triazoles is reported. 4-Chlorophenol was treated with chloroacetic acid to give 4-chlorophenoxy acetic acid (C1) which was reacted with thionyl chloride ...
Mudhar A. Othman, Khalid M. Daoud
doaj   +1 more source

Rational Design of Donor‐Acceptor Oligomers for Enhanced Charge Separation

Advanced Physics Research, Volume 5, Issue 4, April 2026.
How can molecular symmetry be broken to maximize photoinduced charge separation? Through first‐principles analysis of 22 DTP‐based donor‐acceptor ternary oligomers, this work establishes that combining architectural asymmetry with site‐selective acceptor fluorination creates an ideal electrostatic landscape for frontier orbital segregation.
Jannik Theile, Michele Guerrini, Surender Kumar, Caterina Cocchi   +3 more
wiley   +1 more source

Synthesis and Evaluation of Antimicrobial Activity of Tetranorlabdane Compounds Bearing 1,3,4-Thiadiazole Units

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2023
Synthesis of novel tetranorlabdane compounds bearing 1,3,4-thiadiazole units and intermediary tetranorlabdane compounds with thiosemicarbazone fragment has been reported. The structures of the new synthesized compounds were confirmed using IR and 1H, 13C,
Svetlana Blaja, Lidia Lungu, Alexandru Ciocarlan, Nicoleta Vornicu, Aculina Aricu   +4 more
doaj   +1 more source