Results 61 to 70 of about 18,261 (204)
Chemical Biology &Drug Design, Volume 108, Issue 3, September 2026.In silico studies reveal that compound 3c interacts strongly with the active site of the aromatase enzyme. In addition, compound 3c yielded promising results in in vitro enzyme inhibition and cytotoxicity studies. ABSTRACT Breast cancer is one of the most significant diseases in today's world.
Yusuf Özkay +5 more
wiley +1 more source
, 2016 Treatment of 2 molar equiv of (tBuNC)AuCl with 1 equiv of the dipotassium salt of 2,5-dimercapto-1,3,4-thiadiazole, K2(SSS), results in the formation of the crystalline product [(tBuNC)Au]2(SSS) in addition to polymeric material. A crystallographic study
Hubert Schmidbaur (2651485) +2 more
core +1 more source
Future Journal of Pharmaceutical Sciences, 2017 In the present investigation, a series of novel 4 (5-(10-(3-(N,N-dimethylamino)propyl)-10H-phenothiazine-3-yl)-1,3,4-thiadiazo-2-yl) Azo dye/Schiff base derivatives (5a-e & 6a-j) were synthesised by performing diazotization followed by coupling reaction ...
Chandravadivelu Gopi +2 more
doaj +1 more source
Synthesis and Study of Some 4-Chlorophenoxy Methyl Substituted amido1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles from 4-Chloro phenoxy acetic acid [PDF]
مجلة التربية والعلم, 2013 : In this paper the synthesis of some substituted 1,3,4-oxadiazole, 1,3,4-thiadiazoles and 1,2,4-triazoles is reported. 4-Chlorophenol was treated with chloroacetic acid to give 4-chlorophenoxy acetic acid (C1) which was reacted with thionyl chloride ...
Mudhar A. Othman, Khalid M. Daoud
doaj +1 more source
Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies
ChemMedChem, Volume 21, Issue 16, 27 August 2026.A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga +5 more
wiley +1 more source
Thiadiazoles: the appropriate pharmacological scaffolds with leishmanicidal and antimalarial activities: a review [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Leishmaniasis and malaria are serious public health problems in tropical and sub-tropical regions worldwide. Development of drug-resistant strains has disrupted efforts to control the spread of these diseases in the world.
Azar Tahghighi, Fateme Babalouei
doaj +1 more source
An Integrated DNA Nanoprobe for Intranuclear Imaging and In Situ Profiling of OGG1 Activity
Advanced Science, Volume 13, Issue 47, 24 August 2026.The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao +9 more
wiley +1 more source
DFT calculation of the electronic properties of fluorene-1,3,4-thiadiazole oligomers [PDF]
, 2013 Thiadiazole derivatives have been widely employed in the areas of pharmaceutical, agricultural, industrial, and polymer chemistry. The electronic and molecular structures of thiadiazoles are of interest because they have an equal number of valence ...
NORMA ROSARIO FLORES HOLGUIN
core +1 more source
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2023 Synthesis of novel tetranorlabdane compounds bearing 1,3,4-thiadiazole units and intermediary tetranorlabdane compounds with thiosemicarbazone fragment has been reported. The structures of the new synthesized compounds were confirmed using IR and 1H, 13C,
Svetlana Blaja +4 more
doaj +1 more source
Aggregate, Volume 7, Issue 8, August 2026.The noncovalent conformational locks (NoCLs) strategy modulates molecular aggregation to synergistically enhance NIR‐II absorption, NIR‐IIb emission, and photothermal conversion efficiency (PCE). QCF NPs incorporating both S···O and S···N NoCLs achieve concurrent NIR‐IIb emission (1550 nm) and PCE (75%) under low‐power 1064 nm excitation, establishing ...
Xin Chen +7 more
wiley +1 more source