Results 41 to 50 of about 18,261 (204)
Formula of 4-(5-methyl-1,3,4-thiadiazole-2-yl) benzene-1,3-diol (the C1 compound).
, 2019 Formula of 4-(5-methyl-1,3,4-thiadiazole-2-yl) benzene-1,3-diol (the C1 compound).
Katarzyna Bonio (7444475) +7 more
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Synthesis of Novel Pyrazolyl-1,3,4-Thiadiazole Analogues
, 2020 In the present study, we have designed a novel series of pyrazolyl-1,3,4-thiadiazole analogues by accommodating 1,3,4-thiadiazole ring at C - 4 of pyrazole ring with and without an amide linkage; 5-methyl-1,3-diphenyl-N-(5-phenyl-1,3,4-thiadiazol-2-yl ...
Ningaiah, Srikantamurthy +3 more
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Synthesis and characterization of benzylidene- [1,3,4]thaidiazol -2-yl-amine
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2006 This study was designed to synthesize chemically 2-aminothiadiazole derivatives and conversion to Schiff’s base. The principle synthesis of these compounds was to involve three steps: First : by thermal cyclization of thiosemicarbazied with carbon ...
Al-Kaddimy H. A. Ahmed
doaj +1 more source
Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova +3 more
wiley +1 more source
Síntese de novos mesógenos derivados do heterocíclo imidazo[2,1-b][1,3,4]tiadiazol [PDF]
, 2009 TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Química.A síntese de seis novas moléculas derivadas do heterociclo imidazo[2,1-b][1,3,4]tiadiazol foram realizadas a partir da construções de ...
Ferraz Neto, José
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Synthesis and characterization of 1,2,4-triazolo-1,3,4-thiadiazole derivatives [PDF]
, 2022 In this project, a 1,2,4-triazole and a series of 1,2,4-triazolo-1,3,4-thiadiazole derivatives have been successfully synthesized. A total of eight 1,2,4-triazolo-1,3,4-thiadiazole derivatives (YR1-YR8) with different R group substituents (R = H, 2-F, 4 ...
Cheng, Yun Ru
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N-(5-Benzylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(piperidin-1-yl)acetamide
Acta Crystallographica Section E, 2014 The title compound, C16H20N4OS2, was synthesized by the reaction of 2-benzylsulfanyl-5-chloroacetamido-1,3,4-thiadiazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thiadiazole units are twisted by 10.8 (4)°.
D. S. Ismailova +4 more
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Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.Innovative synthesis of a novel benzothiophene–based bis–oxadiazole derivatives. The structural characterization was performed using experimental and theoretical methods. Significant anticancer activity against selected cancer cell lines. Three derivatives showed good activity 7b, 7g and 7i with IC50 values 7.5 ± 1.04 and 9.5 ± 1.01 µg/mL.
Nagaraju Madala +2 more
wiley +1 more source
Solvent Induced Disulfide Bond Formation in 2,5-dimercapto-1,3,4-thiadiazole [PDF]
, 2007 Disulfide bond formation is the decisive event in the protein folding to determine the conformation and stability of protein. To achieve this disulfide bond formation in vitro, we took 2,5-dimercapto-1,3,4-thiadiazole (DMcT) as a model compound. We found
Palraj Kalimuthu +2 more
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Synthesis and Biological Evaluation of Novel Substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1- b] [1,3,4]thiadiazole Derivatives [PDF]
, 2014 A new series of N-[5-(4-(alkyl/aryl)-3-nitro-phenyl)-[1,3,4-thiadiazol-2-yl]-2,2-dimethyl-propionamide 4(ael) and 6-(4-Methoxy-phenyl)-2-(4-alkyl/aryl)-3-nitro-phenyl)-Imidazo [2,1-b] [1,3,4] thiadiazole 6(ael) were synthesized starting from 5-(4-Fluoro ...
Boodappa, Chandrakantha +4 more
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