Results 31 to 40 of about 8,138 (214)

Synthesis and properties of 5-(((5-amino-1,3,4-thiadiazole-2-yl)thio)methyl)-4-phenyl-1,2,4-triazole-3-thione and its some S-derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
Increased attention to thiadiazole and 1,2,4-triazole derivatives is determined by the extensive structural modification capabilities of heterocyclic system derivatives and their high pharmacological potential.
A. S. Hotsulia , S. O. Fedotov
doaj   +1 more source

Formation of Pyrazol-1,3,4-Thiadiazoles through 1,3-Dipolar Cycloadditions of 3-Thioxo-[1,2,4]-Triazepin-5-one with Nitrilimines: An Experimental and Computational study [PDF]

, 2009
In this work the results of experimental and computational study of the title compounds and some ancillary compounds are reported. Two bicyclic pyrazol-1,3,4-thiadiazole derivatives were synthesized by reaction between 6-dimethylaminomethylene-3-thioxo-
Azzouzi, S., Domingo, Luis R., El Messaoudi, M., Esseffar, M., Jalal, R., Latorre, J., Liu González, M., Sáez Cases, José Antonio   +7 more
core   +2 more sources

Synthesis and Evaluation of the Anti-Microbial Activity of New Heterocycles Containing the 1,3,4-Thiadiazole Moiety

Molecules, 2011
A new series of thiadiazole-enaminones 4 were synthesized via reactions of 5-acetyl-1,3,4-thiadiazoles 3 with dimethylformamide-dimethylacetal (DMF-DMA).
Thoraya A. Farghaly, Zienab A. Muhammad, Magda A. Abdallah   +2 more
doaj   +1 more source

Recent synthetic strategies of medicinally important imidazothiadiazoles

Journal of Saudi Chemical Society, 2023
Imidazothiadiazole is a fundamental fused heterocyclic compound containing imidazole and thiadiazole ring systems. This versatile framework has significant applications in pharmaceutical chemistry and also possessed a remarkable biological profile.
Tooba Jabeen, Sana Aslam, Muhammad Yaseen, Muhammad Jawwad Saif, Matloob Ahmad, Sami A. Al-Hussain, Magdi E.A. Zaki   +6 more
doaj   +1 more source

Synthesis of Novel 2,5-Disubstituted-1,3,4-thiadiazoles Clubbed 1,2,4-Triazole, 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and/or Schiff Base as Potential Antimicrobial and Antiproliferative Agents

Molecules, 2015
In the present study, a new series of 2,5-disubstituted-1,3,4-thiadiazole tethered 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole and Schiff base derivatives were synthesized and characterized by IR, 1H-NMR, 13C-NMR, MS and elemental analyses.
Nadjet Rezki, Amjad M. Al-Yahyawi, Sanaa K. Bardaweel, Fawzia F. Al-Blewi, Mohamed R. Aouad   +4 more
doaj   +1 more source

Crystal structure of 6-(2-fluorophenyl)-3-phenyl-[1,2,4]-triazolo[3,4-b][1,3,4]thiadiazole, C15H9FN4S [PDF]

, 2016
C15H9FN4S, orthorhombic, Pna21 (no. 33), a = 18.9361(2) Å, b = 11.5248(1) Å, c = 6.0142(1) Å, V = 1312.52(3) Å3, Z = 4, R gt (F) = 0.0263, wR ref (F 2
Al-Alshaikh, M. A., El-Emam, A. Ali, García-Granda, Santiago, Ghabbour, H. A., Said Mohammed Abdelbaky, Mohammed   +4 more
core   +1 more source

A convenient synthesis of 1,3,4-thiadiazole and 1,3,4-oxadiazole based peptidomimetics employing diacylhydrazines derived from amino acids [PDF]

, 2010
Synthesis of novel orthogonally protected 1,3,4-thiadiazole and 1,3,4-oxadiazole tethered dipeptide mimetics is described. Both the heterocycles are prepared via a set of diacylhydrazines derived from amino acids.
Lamani, R.S., Nagendra, G., Narendra, N., Sureshbabu, V.V.   +3 more
core   +1 more source

Novel spiroheterocycles containing a 1,3,4-thiadiazole unit: Synthesis and spectroscopic characterization

Journal of Chemical Research, 2022
We describe the preparation of a series of novel spiroheterocycles, namely 1,3,4-thiadiazole derivatives possessing an indane unit. These active heterocyclic compounds are prepared starting from thiocarbohydrazide and 2-indanone via an intermediate indan-
Shaymaa K. Alazzawi, Mohammed Hadi Ali Al-Jumaili   +1 more
doaj   +1 more source

Synthesis and Crystal Structure Analysis of 2-(Fluorobenzyl)-6-(4-Nitrophenyl) Imidazo[2,1-b][1,3,4]Thiadiazole [PDF]

, 2010
Preparation of 2-(4-fluorobexzyl)-6-(4-nitrophenyl)imidazo[2,1-b][1,3,4]thiadiazole is described and its crystal structure is discussed. The compound crystallizes in the monoclinic space group C2/c with a = 39.941(6) Å, b = 5.698(2) Å, c = 13.272(5) Å β =
Banu, A., Begum, N.S., Khazi, I.M., Lamani, R.S.   +3 more
core   +1 more source

New Route Synthesis of Thiadiazoles, Bisthiadiazoles, Thiadiazolotriazines, and Pyrazolothiadiazoles Based on Hydrazonoyl Halides and Dihydrazinylthiadiazole

Molecules, 2017
Synthesis and characterization of new thiadiazoles, bisthiadiazoles from the reaction of mono- and di-hydrazonoyl halides with various hydrazinecarbodithioate derivatives were studied.
Abdelwahed R. Sayed, Shar Saad Al-Shihry
doaj   +1 more source