Results 141 to 150 of about 43,074 (261)

Synthesis and biological evaluation of phosphonated dihydroisoxazole nucleosides [PDF]

, 2006
Phosphonated isoxazolinyl nucleosides have been prepared via 1,3-dipolar cycloaddition reaction of nitrile oxides with corresponding vinyl or allyl nucleobases for antiviral studies.
Balestrieri, E, Chiacchio, M, Iannazzo, D, Macchi, B, Mastino, A, Piperno, A, Romeo, G, Romeo, R, Saglimbeni, M   +8 more
core   +1 more source

Coordination Studies of a Triazole‐Substituted 3H‐1,2,4‐Diazaphosphole: CC and CN Bond Activation Induced by Cobalt(0) and Nickel(0) Complexes

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Reactions of a triazole‐substituted 3H‐1,2,4‐diazaphosphole with electron‐rich cobalt and nickel complexes result in the selective cleavage of CC and CN bonds on the triazole, forming chelate complexes with the activated diazaphosphole ligand. The reactivity of the recently reported 3H‐1,2,4‐diazaphosphole 1 toward electron‐rich Ni and Co complexes ...
Sebastian Hauer, Gábor Balázs, Justus Reitz, Max M. Hansmann, Robert Wolf   +4 more
wiley   +1 more source

Highly Regioselective 1,3-Dipolar Cycloaddition of Nitrilimines and Thioaurones Towards Spiro-2-Pyrazolines: Synthesis, Characterization, and Mechanistic Study

Reactions
In this paper, we report a highly regioselective 1,3-dipolar cycloaddition (1,3-DC) reaction of nitrilimines with thioaurone derivatives that afforded the hitherto unreported spiropyrazolines. Spectroscopic and spectrometric data were utilized to confirm
Mohamed Bakhouch, Bouchra Es-Sounni, Ayoub Ouaddi, Khaoula Oudghiri, Mohammed Chalkha, Lahoucine Bahsis, Taoufiq Benali, Mohamed Bourass, Rabiaa Fdil, Mohamed Akhazzane, Mohamed El Yazidi   +10 more
doaj   +1 more source

Catalytic asymmetric synthesis of highly substituted pyrrolizidines [PDF]

, 2012
A catalytic asymmetric double (1,3)-dipolar cycloaddition reaction has been developed. Using a chiral silver catalyst, enantioenriched pyrrolizidines can be prepared in one flask from inexpensive, commercially available starting materials.
Codelli, Julian A., Lim, Andrew D., Reisman, Sarah E.   +2 more
core  

Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines [PDF]

, 2014
The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
Antonow, Broggini, Christopher Chambers, Faisal Jamshaid, Karl Hemming, Mitra, Patel, Paul O'Gorman, Rahman, Thurston   +9 more
core   +2 more sources

Electrochemical Dehydration Reaction

ChemSusChem, Volume 18, Issue 20, October 23, 2025.
Electrochemical dehydration reactions are a fascinating and underexplored field of research in the domain of electrosynthesis. They offer a sustainable alternative to hazardous and harsh dehydration reagents. In this review, the recent progress that has been made in this emerging research topic is surveyed.
Johannes Schneider, Enrico Lunghi, Siegfried R. Waldvogel   +2 more
wiley   +1 more source

Visible-Light-Mediated Anti-Regioselective Nitrone 1,3-Dipolar Cycloaddition Reaction and Synthesis of Bisindolylmethanes.

Organic Letters, 2017
The development of photoredox reactions of 1,3-dipolar cycloaddition of nitrones with alkenes is reported. It offers an efficient synthetic method to obtain isoxazolidine derivatives under mild conditions in synthetically useful yields.
Lewei Zheng, Fei Gao, C. Yang, Guo-Lin Gao, Yating Zhao, Yuan Gao, W. Xia   +6 more
semanticscholar   +1 more source

Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways

ChemMedChem, Volume 20, Issue 20, October 15, 2025.
Compound 2, identified through in‐house screening and derived from SP18, exhibits high affinity for BAG3, as demonstrated by Surface Plasmon Resonance and docking studies. It induces a dose‐dependent proapoptotic response in HeLa cells, evidenced by increased Annexin V/PI staining, underscoring the triazole scaffold as a promising platform for BAG3 ...
Dafne Ruggiero, Eleonora Boccia, Emis Ingenito, Vincenzo Vestuto, Gilda D’Urso, Alessandra Capuano, Agostino Casapullo, Stefania Terracciano, Giuseppe Bifulco, Gianluigi Lauro, Ines Bruno   +10 more
wiley   +1 more source

Synthesis of highly functionalized β-aminocyclopentanecarboxylate stereoisomers by reductive ring opening reaction of isoxazolines

Beilstein Journal of Organic Chemistry, 2012
A rapid and simple procedure was devised for the synthesis of multifunctionalized cyclic β-amino esters and γ-amino alcohols via the 1,3-dipolar cycloaddition of nitrile oxides to β-aminocyclopentenecarboxylates.
Melinda Nonn, Loránd Kiss, Reijo Sillanpää, Ferenc Fülöp   +3 more
doaj   +1 more source

Synthesis and Characterization of some New Mesoionic 1,3-Thiazolium-5-thiolates via Cyclodehydration and in situ 1,3-Dipolar Cycloaddition/Cycloreversion

Molecules, 2002
The title compounds were synthesized from C-aryl-N-methylglycines by Naroylation followed by a cyclodehydration to form the corresponding 1,3-oxazolium-5-olates.
Maria Joaquina Vieira, Aderson de Farias Dias, Alfredo Mayall Simas, Joseph Miller, Petrônio Filgueiras de Athayde Filho, Bruno Freitas Lira   +5 more
doaj   +1 more source